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GABA vs Melatonin

Evidence-based comparison from our database of 3,862 ingredients

TL;DR

GABA is typically chosen for evening wind-down, while Melatonin is used for sleep onset. Neither outranks the other. The right pick depends on the goal, and the two are not interchangeable.

GABA

The brain's brake pedal.

Research depthStudied
Effective Dose500-750mg
Time to EffectEffects within minutes to hours

Commonly used for:

Evening wind-downRacing thoughts at bedtimeNerves before a big day

Melatonin

The vampire hormone.

Research depthExtensively studied
Effective Dose0.3mg - 5mg
Time to EffectEffects within minutes to hours

Commonly used for:

sleep onsetjet lagshift work

Side-by-Side Comparison

FactorGABAMelatonin
Research depthStudiedExtensively studied
Effective Dose500-750mg0.3mg - 5mg
Time to EffectEffects within minutes to hoursEffects within minutes to hours
Commonly used forEvening wind-down, Racing thoughts at bedtimesleep onset, jet lag

Which fits which goal

These two do different jobs, so the comparison ends at the goal, not at a ranking. Match the ingredient to what you are trying to change and check the dose against the amount on the label.

Reach for GABA when:

  • • The goal is evening wind-down
  • • The goal is racing thoughts at bedtime

Reach for Melatonin when:

  • • The goal is sleep onset
  • • The goal is jet lag

Frequently Asked Questions

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This comparison is for informational purposes only and should not replace professional medical advice. Always consult a healthcare provider before starting any supplement regimen, especially if you have existing health conditions or take medications.