SPECIMEN #NATURE-M
Verified
VitaminsNature Made
Vitamin E 400 IU
High-dose synthetic vitamin E is one of the most debunked supplement trends. SELECT trial: no cancer prevention. Meta-analyses: may increase mortality. Synthetic form depletes gamma-tocopherol (the important one). Eat nuts instead. Seriously.
4.5/10
POOR400 IU synthetic dl-alpha tocopherol is at the diminishing returns point and uses the inferior synthetic form. The SELECT trial found no cancer prevention benefit. Meta-analyses (Miller 2005) suggest high-dose synthetic vitamin E may increase all-cause mortality. Natural mixed tocopherols at lower doses would be far safer and more effective.
1 ingredientSoftgels100 servings
Evidence
7.0
Dosing
6.7
SynergyN/A (single ingredient)
What We Like
- 100 softgels.
- USP Verified.
Watch Out For
- Synthetic dl-alpha has 50% bioactivity of natural d-alpha.
- SELECT trial: no cancer prevention benefit.
- Meta-analyses: high-dose synthetic E may increase mortality.
- Displaces gamma-tocopherol (which may be more important).
- The entire high-dose isolated vitamin E approach is outdated.
What We Analyzed
Verified Supplement Facts
Every dose checked against clinical research
We analyzed the actual supplement facts panel for this product. Every ingredient dose below was cross-referenced with published clinical trials to determine if it matches what studies actually use.
1 ingredients analyzed
Source: Official product page
Ingredient Breakdown
1 adequate
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
In our database (click to learn more) Not yet reviewed
Our Analysis
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