Folate at 8500mcg DFE as 5-MTHF (methylfolate). The bioactive form bypasses the MTHFR enzyme entirely. Well above the 1000mcg UL for folic acid, but methylfolate has a better safety profile than folic acid at high doses.
The set is generated, never written by the brand.
Life Extension Life Extension Optimized Folate: the formulation holds up. Lead: Folate at 8500 mcg. Folate at 8500mcg DFE as 5-MTHF (methylfolate). Clinical dose on the primary, and the panel holds together.
High-potency folate for heart and brain health.. The database flagged this as underdosed due to a unit conversion error. 8.5 mg is actually 8,500 mcg. That is a massive, therapeutic dose of the bioactive L-5-MTHF form. It is perfect for those who need serious homocysteine support.
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Also on the label (inactive): microcrystalline cellulose, dicalcium phosphate, stearic acid, croscarmellose sodium, silica, vegetable stearate

This read comes from the product's own supplement facts panel. Every dose was cross-referenced with published clinical trials to see whether it matches what the studies actually used.

