iMD
IngredientMDYour supplements, diagnosed.
Analyze StackMy Health
All Products
T
Thorne
SPECIMEN #THORNE-D
Verified
MOODThorne

Deproloft-HF

Multi-pathway mood support: 5-HTP for serotonin, saffron for mood, rhodiola for stress resilience, chromium for blood sugar stability. DO NOT take with SSRIs (serotonin syndrome risk). For people not on antidepressants wanting natural mood support.

7.8/10
VERY GOOD

Multi-pathway mood formula: 5-HTP at 50mg (minimum effective for serotonin), rhodiola at 200mg with 3% rosavins (50% optimal for stress), saffron (affron) at 15mg (minimum effective for mood), and chromium picolinate at 100mcg (50% optimal for blood sugar mood connection). Each ingredient targets a different mood pathway (serotonin, cortisol, dopamine/serotonin, insulin). Thoughtful practitioner formulation. No single ingredient is at optimal, but the multi-pathway approach may provide broader benefit.

4 ingredientsCapsules30 servings
Evidence
7.0
Dosing
4.0
Synergy
6.0
Analyze My Stack

What We Like

  • 5-HTP directly increases serotonin synthesis.
  • Saffron (affron) has clinical trials for mood.
  • Rhodiola at 200mg for stress resilience.
  • Chromium for blood sugar-mood connection.
  • Multi-pathway approach.

Watch Out For

  • 5-HTP at 50mg is conservative (studies use 100-300mg).
  • Saffron at 15mg is half the studied dose (30mg).
  • Must not combine 5-HTP with SSRIs (serotonin syndrome risk).

Ingredient Breakdown

4 underdosed
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
5-HTP8.0

from Griffonia simplicifolia

50 mgUNDERDOSED
33%
50 mg

of 150mg

UNDERDOSED
33%
Saffron Extract

affron, 3.5% Lepticrosalides

15 mgUNDERDOSED
50%
15 mg

of 30mg

UNDERDOSED
50%
Rhodiola8.0

3% Rosavins

200 mgUNDERDOSED
50%
200 mg

of 400mg

UNDERDOSED
50%
Chromium8.0

Chromium Picolinate

100 mcgUNDERDOSED
25%
100 mcg

of 400mcg

UNDERDOSED
25%
In our database (click to learn more) Not yet reviewed

Our Analysis

Personalized Deep Analysis

See exactly how this fits your health profile. What works for you, what doesn't, and whether you're getting your money's worth.

Unlock with Pro

Taking other supplements too?

Check your full stack for interactions, redundancies, and gaps. Takes 30 seconds.

Analyze My Stack
0 views