Backed by human trialsGaia Herbs, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Gaia Herbs.
Holy Basil is the lead active here, studied most for everyday stress. In the 363 mg Proprietary Extract Blend with one other, listed first. 2 human studies on Holy Basil back this formula, each one cited. Who it fits: for everyone, adults.
Clinically dosedFull label disclosure
3Active ingredients2Human studies
Verified by IngredientMDGaia HerbsIngredientMD
The verdict
Backed by human trials
For everyone, adults.
How we verify
The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.
The formula
Proprietary Extract Blend: A 363 mg blend of two ingredients, listed by weight.Supporting role
Holy Basil: Everyday stress. In the 363 mg Proprietary Extract Blend with one other, listed first.Key driver
Eugenols: Oral health. In the 363 mg Proprietary Extract Blend with one other, listed second.Supporting role
The panel on the left is the one we evaluated, line by line.
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Every active, separately.
All 3 actives checked against the clinical evidence: dose, form, and what the research actually shows.
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Then the formula as a whole.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".
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Earned, not bought.
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
The receipts
2
Human studies
363 mg per serving sits inside the studied 300 mg-600 mg range
Meets the studied dose
Holy Basil, Jamshidi 2017 systematic review
Cross-checked against 64 documented interactions for these actives.
Every one of these is a fact the engine could ground.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Studied in people2 human studies on Holy Basil back this formula, each one cited.
A mechanism that is settledHow Holy Basil and Eugenols work is settled pharmacology.
Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
The exact form, describedThe label names its forms exactly: Tulsi leaf (Ocimum tenuiflorum), Isolated eugenol. The record says what each one is and what it suits.
A declared blend totalProprietary Extract Blend declares its total, 363 mg per serving, with 2 ingredients listed by weight.
Where it comes from and how it is madeHoly Basil is made by botanical.
Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
General timing
How each ingredient usually behaves over time.
Two ingredients, from each one's own page.
Holy BasilAbout two to four weeks
Herbal stress support tends to build over two to four weeks of daily use rather than landing on the first day.
On the gum, the numbing sensation arrives within a couple of minutes. Swallowed, it works quietly and shows up in lab measures rather than as a feeling.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
Format
Capsule
It is a capsule, so the amount per serving is fixed and travels without measuring.
Best forMost standard doses, and anywhere a short, clean label is the point.
From the same shelf
Studied alongside this brand's other formulas
Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.
Holy Basil Leaf + Ashwagandha RootPromising
Holy basil and ashwagandha are both examined for effects on hypothalamic-pituitary-adrenal signalling rather than on a single receptor. Because their phytochemistry differs (eugenol and ursolic acid versus withanolides), a combined preparation is not simply a larger dose of one plant. Human data for the pairing come from mixed formulas, so the effect of each component cannot be separated out. Anyone already using a sedating product should account for the combined load.
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Holy Basil Leaf?
Holy Basil Leaf is built on Proprietary Extract Blend, Holy Basil, Eugenols. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 64 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
