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Pure Encapsulations
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MOODPure Encapsulations

Emotional Wellness

Saffron extract (affron) has 8+ clinical trials showing mood improvement comparable to low-dose Prozac. 30mg is the exact studied dose. P-5-P B6 and methylfolate support serotonin synthesis. This is mood support with actual evidence behind it.

8.5/10
EXCELLENT

Evidence-based mood support formula. Saffron extract (affron) at 30mg is the clinical dose from 8+ trials showing mood benefits comparable to low-dose SSRIs. Methylfolate (5-MTHF) at 400mcg supports neurotransmitter synthesis. B12 as methylcobalamin at 500mcg is good. B6 as P-5-P (active form) at 20mg is in the therapeutic range. Every ingredient serves the purpose with evidence behind it.

4 ingredientsCapsules30 servings
Evidence
7.0
Dosing
7.0
Synergy
6.0
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What We Like

  • Saffron (affron) has 8+ RCTs for mood with consistent positive results.
  • 30mg matches the clinical dose exactly.
  • P-5-P is the active form of B6 (directly supports serotonin synthesis).
  • Methylfolate for MTHFR-safe neurotransmitter support.

Watch Out For

  • Premium Pure Encapsulations pricing.
  • Only 30 servings.
  • Not a replacement for clinical treatment of depression.

Ingredient Breakdown

1 clinical1 adequate2 underdosed
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
Saffron Extract

affron, 3.5% Lepticrosalides

30 mgCLINICAL
100%
30 mg

of 30mg

CLINICAL
100%
Folate10.0

5-MTHF Methylfolate

400 mcg DFEUNDERDOSED
50%
400 mcg DFE

of 800mcg

UNDERDOSED
50%
Vitamin B1210.0

Methylcobalamin

500 mcgUNDERDOSED
50%
500 mcg

of 1000mcg

UNDERDOSED
50%
Vitamin B6

P-5-P Pyridoxal-5-Phosphate

20 mgADEQUATE
80%
20 mg

of 25mg

ADEQUATE
80%
In our database (click to learn more) Not yet reviewed

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