The people it speaks toFieldwork April 11 to 15, 2024
8% of US adults
said they rarely or never drink water, in a Yahoo News and YouGov poll of 1,746 US adults fielded in April 2024.
YouGov, 2024Uridine Monophosphate 300mg
Uridine Monophosphate 300mg.
Backed by human trials
Uridine 5'-monophosphate disodium salt is the lead active here, studied most for hydration. 11 human studies on Uridine 5'-monophosphate disodium salt back this formula, each one cited. Who it fits: for everyone, adults.
Full label disclosure
1Active ingredient11Human studies300 mgUridine 5'-monophosphate disodium salt
Verified by IngredientMDHow we read this product
- 01We read the label.
The panel on the left is the one we evaluated, line by line.
- 02Every active, separately.
All 1 actives checked against the clinical evidence: dose, form, and what the research actually shows.
- 03Then the formula as a whole.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".
- 04Earned, not bought.
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
The receipts
11
Human studies
300 mg
Uridine 5'-monophosphate disodium salt
Cross-checked against 11 documented interactions for these actives.
Read the evidenceUridine 5'-monophosphate disodium salt, the evidence →
Inside the formula
In context
The gap this formula speaks to.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
The people it speaks toFieldwork 2009 to 2012
3.46 liters of water a day
was the average total water intake for US men aged 20 and over from 2009 to 2012, about a quarter liter under the 3.7 liters set as adequate intake by the Institute of Medicine, in the National Health and Nutrition Examination Survey.
CDC National Center for Health Statistics, 2016The people it speaks toFieldwork 2009 to 2012
2.75 liters of water a day
was the average total water intake for US women aged 20 and over from 2009 to 2012, close to the 2.7 liters set as adequate intake by the Institute of Medicine, in the National Health and Nutrition Examination Survey.
CDC National Center for Health Statistics, 2016The people it speaks toFieldwork 2011 to 2014
49% of US adults
drank a sugar-sweetened beverage on a given day from 2011 to 2014, in the National Health and Nutrition Examination Survey, reported by the CDC National Center for Health Statistics.
CDC National Center for Health Statistics, 2017The people it speaks toFieldwork 2005 to 2008
40% of US adult women
drank a sugar drink on a given day from 2005 to 2008, in the National Health and Nutrition Examination Survey, reported by the CDC National Center for Health Statistics.
CDC National Center for Health Statistics, 2011Daily usePublished 2024
59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 20247 more
61% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Randomised trial, 2026
Compared combined beta-alanine plus sodium bicarbonate against each alone on physical capacity measures in trained participants. The design is what makes the comparison informative for stacking decisions.
International Journal of Sports Physiology and PerformanceRandomised trial, 2020
In a controlled dietary intervention in adults, changing sodium and potassium intake shifted how the body handled calcium and phosphate, indicating that sodium intake affects normal mineral balance.
The Journal of Clinical Endocrinology and MetabolismRandomised trial, 2026
Microencapsulated sodium butyrate was tested against abdominal symptom scores and carbohydrate metabolism markers in adults with high blood sugar. Again a butyrate trial in which sodium is the carrier salt.
Scientific ReportsPanufnik et al., 2026 (Scientific Reports)PMID 41974937
Systematic review, 2026
A systematic review catalogued gastrointestinal symptoms reported across sodium bicarbonate dosing protocols and described how symptom burden varies with dose, timing and whether the dose is split or given with food.
European Journal of Sport ScienceRandomised trial, 2026
A randomised trial tested an algorithm-driven sodium supplementation protocol against usual care and measured growth in infants born preterm.
Pediatrics Open ScienceLiberio et al., 2026 (Pediatrics Open Science)PMID 42453289
Randomised trial, 2025
In a trial of 104 very preterm infants, oral sodium supplementation raised daily weight gain by 3.6 grams per kilogram compared with placebo.
BMJ Paediatrics OpenAmiti et al., 2025 (BMJ Paediatrics Open)PMID 40659450
Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Every one of these is a fact the engine could ground.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
- Studied in people11 human studies on Uridine 5'-monophosphate disodium salt back this formula, each one cited.
- A mechanism that is settledHow Uridine 5'-monophosphate disodium salt works is settled pharmacology.
- Recent work on the recordThe most recent study on this record was published in 2026.
- Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
- The exact form, describedThe form on the label is Sodium chloride, table salt, sea salt. The record says what that form is and what it suits.
- Full label disclosureEvery ingredient on this label carries its own declared amount.
- Where it comes from and how it is madeUridine 5'-monophosphate disodium salt is made by mineral.
- Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
- A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
What the trials show
What the trials show about timing.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
- EarlyUridine 5'-monophosphate disodium saltabout 3 days to 4 weeks of steady intakeBuilds with daily use
In the excretion studies the EFSA reference opinion reviews, urinary output closely tracked dietary sodium once intake was held steady: 98% of dietary sodium appeared in 24-hour urine in a 3-day study, and 86% of sodium ingested over 4 weeks was recovered in 24-hour urine collected during the same period.
- PromisingUridine 5'-monophosphate disodium saltabout 29 days at each fixed intake levelBuilds with daily use
In the controlled metabolic study the EFSA reference opinion reviews, young men held at constant sodium intakes for 29 days per level showed rising average daily urinary aldosterone excretion as intake was stepped down from 4.9 g/day to 2.5 g/day.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
How each ingredient usually behaves over time.
One ingredient, from its own page.
- Uridine 5'-monophosphate disodium salt
Fast. Sodium shifts fluid within an hour or two, which is why an electrolyte drink lands quickly when you have been sweating.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
Capsule
It is a capsule, so the amount per serving is fixed and travels without measuring.
Best forMost standard doses, and anywhere a short, clean label is the point.
Questions shoppers ask
- Is Uridine Monophosphate 300mg independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in Uridine Monophosphate 300mg?
- Uridine Monophosphate 300mg is built on Uridine 5'-monophosphate disodium salt. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against 11 documented interactions for these actives in IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
Independent review by IngredientMD, not commissioned by Double Wood SupplementsWork at Double Wood Supplements? This verification is yours to claim →