24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 2022Saccharomyces boulardii CNCM I-745 is the lead active here, studied most for gut barrier integrity. 7 human studies on Saccharomyces boulardii CNCM I-745 back this formula, each one cited. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 1 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 202252% of US adults
believe common digestive symptoms such as bloating and abdominal pain are just a normal part of life, per a 2026 Harris Poll conducted for Oshi Health.
The Harris Poll for Oshi Health, 202658% of the recommended fiber intake
was reached on average by US consumers, who ate 8.1 grams of fiber per 1,000 calories in 2017 to 2018 versus the 14 grams recommended, per USDA Economic Research Service analysis of federal food consumption survey data.
USDA Economic Research Service, 202340% of US adults
aged 18 and over report they experience bloating at least a few times a month, with 5% saying they experience it daily, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202334% of US adults
aged 18 and over report they experience abdominal discomfort or pain at least a few times per month, with women about twice as likely as men to report it several times weekly, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202328% of US adults
aged 18 and over say that digestive issues impact the quality of their life, a share that rises to about a third among those aged 18 to 44, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202332% of US adults
say they actively try to consume probiotics, and among them 60% try to do so at least once a day, per a 2022 IFIC survey on gut health.
International Food Information Council, 202259 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Randomised trial, 2017
Taking a yeast probiotic alongside an antibiotic course was linked to smaller shifts in gut bacteria than the antibiotic alone, in a randomized study.
Gut MicrobesCohort study, 2026
A real-world registry analysis reports effectiveness and tolerability figures for the yeast used as an adjunct. Being observational, it describes association within routine practice and not causation.
HelicobacterRandomised trial, 2023
In adults with sudden onset loose stools, the CNCM I-745 strain shortened the time taken for stool form and bowel frequency to return to normal compared with usual care.
BMC GastroenterologyRandomised trial, 2020
In students supplemented ahead of examinations, the yeast shifted stress-related blood markers, while examination performance itself did not differ detectably from placebo.
NutrientsRandomised trial, 2016
In preterm infants, the CNCM I-745 strain improved feeding tolerance and shortened time to full feeds. Growth measures did not differ detectably between groups.
Jornal de PediatriaMeta-analysis, 2024
Pooling trials of a four-drug antibacterial regimen with and without the yeast, the authors report differences in reported digestive complaints during therapy.
Frontiers in MedicinePopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
One ingredient, from its own page.
To reach steady levels in the gut, with most reports of steadier regularity inside the first week of daily use.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
It is a capsule, so the amount per serving is fixed and travels without measuring.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.