12% of US adults
regularly reported feelings of worry, nervousness, and anxiety in 2024, in the National Health Interview Survey.
CDC National Center for Health Statistics, 2024Ashwagandha is the lead active here, studied most for everyday stress. In the 350 mg Proprietary Extract Blend, listed first. 21 human studies on Ashwagandha back this formula, each one cited. Each serving carries 350 mg of Ashwagandha, inside the range the published research used. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 3 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong for its niche".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Cross-checked against 14 documented interactions for these actives.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
12% of US adults
regularly reported feelings of worry, nervousness, and anxiety in 2024, in the National Health Interview Survey.
CDC National Center for Health Statistics, 202439% of adults worldwide
said they worried a lot the previous day, in the Gallup World Poll fielded in 2024 across 144 countries and territories.
Gallup, 202437% of adults worldwide
said they felt stressed the previous day, in the Gallup World Poll fielded in 2024 across 144 countries and territories.
Gallup, 202457.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Meta-analysis, 2022
Pooling trials, ashwagandha lowered self-reported anxiety and stress scores compared with placebo.
Phytotherapy researchMeta-analysis, 2025
In a pooled analysis of supplement trials, ashwagandha was among the interventions linked with better self-reported sleep quality.
NutrientsRandomised trial, 2026
A placebo-controlled trial of low-dose ashwagandha supplementation reported exercise endurance measures over the supplementation period.
Phytotherapy ResearchSystematic review, 2026
Reviewing human trials, withanolide-bearing Withania somnifera extracts were associated with modest gains in cognitive test scores and physical function measures.
Frontiers in pharmacologySystematic review, 2023
Across randomised trials in adults under stress, withanolide-standardised Withania somnifera extracts lowered circulating cortisol compared with placebo.
NutrientsMeta-analysis, 2024
Pooling nine randomized trials in 558 adults, ashwagandha lowered perceived stress scores by about 4.7 points and serum cortisol by about 2.6 micrograms per deciliter compared with placebo.
ExploreMeta-analysis, 2021
Across five randomized trials in 400 adults, ashwagandha extract improved overall sleep with a small pooled effect (standardized mean difference -0.59), most noticeable at doses of 600 mg or more per day taken for at least eight weeks.
PLoS OneMeta-analysis, 2020
Pooling four randomized trials in 142 athletes and healthy adults, ashwagandha raised maximal oxygen uptake (VO2max) by about 3.0 mL/kg/min compared with placebo.
NutrientsMeta-analysis, 2026
Across randomised trials, ashwagandha supplementation was associated with small gains in exercise performance measures such as strength and oxygen uptake.
NutrientsNarrative review, 2026
A narrative review of ashwagandha in physical performance contexts, mapping the reported strength, recovery and endurance measures and the limits of the trial base.
Nutrition and MetabolismRandomised trial, 2025
Supplementation with a standardised ashwagandha formulation was reported to improve self-rated stress, mood and sleep quality scores. These are questionnaire ratings rather than clinical endpoints.
Advances in TherapyRandomised trial, 2025
A single-dose crossover trial found higher blood levels of active compounds from a 1.5 percent standardised ashwagandha formula than from a comparison product. This measures absorption, not a functional benefit.
Advances in TherapyPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
In a 60 day randomised, double-blind, placebo-controlled trial, 60 stressed healthy adults took 240 mg of a standardised ashwagandha extract (Shoden) once daily or placebo. The ashwagandha arm showed a larger fall in Hamilton Anxiety Rating Scale scores (p = .040) and in morning cortisol (p < .001) than placebo, with the DASS-21 change near-significant (p = .096). A separate 8 week randomised, double-blind, placebo-controlled dose-ranging trial enrolled 131 adults with self-reported high stress and analysed 98, measuring reduced Perceived Stress Scale scores at 125, 250 and 500 mg per day of an aqueous root and leaf extract. Two trials on two different extracts, both landing in the same eight to nine week band.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
Two ingredients, from each one's own page.
Give it two to four weeks. Morning cortisol shifts on a blood draw before a calmer week is something you'd describe out loud.
Some people notice a calmer edge within the first few days. The measured changes in stress-hormone rhythm build across two to four weeks.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
It is a capsule, so the amount per serving is fixed and travels without measuring.
Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.
Rhodiola and withanolide-bearing ashwagandha are both described in adaptogen reviews as acting on stress-response signalling, including the hypothalamic-pituitary-adrenal axis. Rhodiola is usually taken in the morning and withanolides at either end of the day. The combination is a traditional and commercial pairing. The shared axis is the rationale, not a measured additive effect.
Holy basil and ashwagandha are both examined for effects on hypothalamic-pituitary-adrenal signalling rather than on a single receptor. Because their phytochemistry differs (eugenol and ursolic acid versus withanolides), a combined preparation is not simply a larger dose of one plant. Human data for the pairing come from mixed formulas, so the effect of each component cannot be separated out. Anyone already using a sedating product should account for the combined load.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.