Alpha GPCNHANES 2009 to 2012
Fewer than 1 in 10 Americans
take in enough choline to meet the adequate intake.
Peer-reviewed analysisAlpha GPC 300mg
Alpha GPC 300mg.
Strong evidence, strong dose
Alpha GPC is the lead active here, studied most for focus and clear thinking. 6 human studies on Alpha GPC back this formula, each one cited. Each serving carries 300 mg of Alpha GPC, inside the range the published research used. Who it fits: for everyone, adults.
Clinically dosedFull label disclosure
1Active ingredientWell studiedResearch base6Human studies
Verified by IngredientMDHow we read this product
- 01We read the label.
The panel on the left is the one we evaluated, line by line.
- 02Every active, separately.
All 1 actives checked against the clinical evidence: dose, form, and what the research actually shows.
- 03Then the formula as a whole.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".
- 04Earned, not bought.
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
The receipts
Well studied
Research base
6
Human studies
300 mg
Alpha GPC
300 mg per serving sits inside the studied 300 mg-600 mg range
Alpha GPC, Parker 2015 + Bellar 2015 power output study
Cross-checked against 22 documented interactions for these actives.
Read the evidenceAlpha GPC, the evidence →
Inside the formula
In context
The gap this formula speaks to.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
The people it speaks toFieldwork March to April 2024
25% of employed US adults
reported difficulty focusing at work in the past month, in the American Psychological Association's 2024 Work in America survey.
American Psychological Association and The Harris Poll, 2024The people it speaks toFieldwork 2011
12.7% of US adults aged 60 and over
in 21 states reported increased confusion or memory loss in the preceding 12 months, in the 2011 Behavioral Risk Factor Surveillance System.
CDC, MMWR Surveillance Summaries, 2015The people it speaks toFieldwork April 2017
17% of US adults
reported trouble focusing over the past year, in a 2017 Ipsos poll of 1,008 adults.
Ipsos, 2017The people it speaks toFieldwork 2013 to 2023
7.4% of US adults
reported serious difficulty concentrating, remembering or making decisions in 2023, up from 5.3% in 2013, and among adults aged 18 to 39 the share nearly doubled, from 5.1% to 9.7%, in the Behavioral Risk Factor Surveillance System.
Neurology, 2025The people it speaks toPublished June 2019
More than 1 in 4 US adults aged 50 to 73
regularly take a supplement for their brain health, rising to 36% of those over 74, and memory is the reason 71% give, in AARP's 2019 survey.
AARP, 20198 more
53% of US adults
say they spend too much time on their smartphone, about 7 in 10 of adults under 30, in a Pew Research Center survey of 9,750 adults in 2026.
Pew Research Center, 202659 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Randomised trial, 2015
Six days of 600 mg alpha-GPC increased lower-body peak force on an isometric mid-thigh pull versus placebo in college-aged men (about +99 N versus -39 N).
Journal of the International Society of Sports NutritionRandomised trial, 2017
Over seven days, alpha-GPC produced a group difference in countermovement jump peak power and velocity in healthy college-aged men, with the 250 mg dose showing the largest improvement.
Journal of the International Society of Sports NutritionCohort study, 2024
A genetic-instrument analysis of serum metabolites and a dermatological outcome that names glycerophosphocholine among the metabolites examined. This is an association between a circulating measure and an outcome, not evidence that supplementation changes anything.
Frontiers in ImmunologyYang et al., 2024 (Frontiers in Immunology)PMID 38529280
Randomised trial, 2026
Comparing four choline forms in preterm infants, the study measured blood choline levels only, a marker of delivery rather than a health outcome.
European Journal of NutritionRandomised trial, 2024
A single 630 mg dose of alpha-GPC improved attention and processing speed on the Stroop test in healthy resistance-trained men, with a score change of 13.0 versus 5.2 for placebo.
NutrientsKerksick et al., 2024 (Nutrients)PMID 39683633
Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Every one of these is a fact the engine could ground.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
- Studied in people6 human studies on Alpha GPC back this formula, each one cited.
- A mechanism that is settledHow Alpha GPC works is settled pharmacology.
- Serving amount inside the studied rangeEach serving carries 300 mg of Alpha GPC, inside the range the published research used.
- A stated daily maintenance amountAlpha GPC is here at a daily maintenance amount, which is what a daily supplement is for.
- Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
- The exact form, describedThe form on the label is Alpha-GPC 50%. The record says what that form is and what it suits.
- Full label disclosureEvery ingredient on this label carries its own declared amount.
- Where it comes from and how it is madeAlpha GPC is made by more than one route.
- Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
- A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
How each ingredient usually behaves over time.
One ingredient, from its own page.
- Alpha GPCWithin one to two hours
Focus effects land within one to two hours of a dose. The power output work measured on that same acute timescale, so this is a same-day ingredient rather than a slow build.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
Capsule
It is a capsule, so the amount per serving is fixed and travels without measuring.
Best forMost standard doses, and anywhere a short, clean label is the point.
Studied alongside this brand's other formulas
Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.
Alpha GPC 300mg + B-Right ComplexEstablished
Alpha-GPC is a choline carrier, so its choline counts toward the same daily pool as free choline and the two overlap rather than add independently.
same nutrient pool. No combination trial has tested this exact pairing.
Available from Jarrow Formulas
Strong evidence, strong doseVerified Oct 2026
Questions shoppers ask
- Is Alpha GPC 300mg independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in Alpha GPC 300mg?
- Alpha GPC 300mg is built on Alpha GPC. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against 22 documented interactions for these actives in IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
Independent review by IngredientMD, not commissioned by Jarrow FormulasWork at Jarrow Formulas? This verification is yours to claim →