Skip to main content
Verified by IngredientMD/Life Extension/Potassium with Extend-Release Magnesium
VERIFIED BYingredientMD

Potassium with Extend-Release Magnesium.

Strong evidence, strong doseLife Extension, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Life Extension.

Magnesium is the lead active here, studied most for winding down in the evening. 21 human studies on Magnesium back this formula, each one cited. Each serving carries 250 mg of Magnesium, inside the range the published research used. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
2Active ingredientsWell studiedResearch base37Human studies
Potassium with Extend-Release MagnesiumVerified by IngredientMD
Life ExtensionIngredientMD
The verdict
Strong evidence, strong dose
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Magnesium: Winding down in the eveningKey driver
Potassium: Electrolyte balanceExtensively studied

How we read this product

Source: Supplement facts
Supplement Facts panel for Potassium with Extend-Release Magnesium
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
37
Human studies
250 mg
Magnesium
99 mg
Potassium
250 mg per serving sits inside the studied 200 mg-400 mg range
Magnesium, NIH Office of Dietary Supplements + Rosanoff 2012 meta-analysis

Cross-checked against 453 documented interactions for these actives.

Read the evidenceMagnesium, the evidence →Potassium, the evidence →

Inside the formula

Magnesium
21 studies
Winding down in the evening
Studied 200 mg to 600 mg a day
Key driver
Potassium
16 studies
Electrolyte balance
Extensively studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
Daily usePublished 2024

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
4 more
Magnesium

Randomised trial, 2012

In 46 older adults with poor sleep, eight weeks of magnesium improved their scores on a sleep questionnaire against placebo.

older adults with poor sleep
Magnesium

Systematic review, 2024

Across exercise studies, magnesium was linked to less muscle soreness and better recovery, with people training hard possibly needing 10 to 20 percent more than sedentary people.

Journal of Translational Medicine
Magnesium

Randomised trial, 2026

In one trial, 20 adults on an antidepressant added magnesium, and low mood scores changed over six weeks, with the antidepressant doing part of the work by design.

East Asian Archives of Psychiatry
Magnesium

Meta-analysis, 2025

Across over 20 trials, magnesium raised HDL cholesterol by about 1.2 mg/dL but showed no clear change in LDL, total cholesterol or triglycerides.

Nutrition Journal

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people21 human studies on Magnesium back this formula, each one cited.
  • A mechanism that is settledHow Magnesium and Potassium work is settled pharmacology.
  • Studied together, not just separatelyMagnesium and Potassium have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Serving amount inside the studied rangeEach serving carries 250 mg of Magnesium, inside the range the published research used.
  • A stated daily maintenance amountMagnesium is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
  • The exact form, describedThe label names its forms exactly: Magnesium oxide, Potassium chloride. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeMagnesium is made by mineral.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
How much it moves the numbers

The size of the effect, in plain numbers.

Where a trial measured an actual number, we show it next to the claim. It is the average across the trials, never a promise about one person.

Magnesiumsystolic blood pressure
Average change in the trials

About 2 mmHg lower systolic and 1.8 mmHg lower diastolic, on average across the trials.

Measured in
adults, at a median 368 mg per day for about 3 months
Confidence interval
systolic 0.4 to 3.6 mmHg lower

Read at the source. The magnitude sits beside the same trial the claim already cites. It describes what the trials measured, never what any one person will feel.

General timing

How each ingredient usually behaves over time.

Two ingredients, from each one's own page.

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Format

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Best forMost standard doses, and anywhere a short, clean label is the point.

Questions shoppers ask

Is Potassium with Extend-Release Magnesium independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Potassium with Extend-Release Magnesium?
Potassium with Extend-Release Magnesium is built on Magnesium, Potassium. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 453 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?

Put an earned verification on your own product page.

Get verified

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

Independent review by IngredientMD, not commissioned by Life ExtensionWork at Life Extension? This verification is yours to claim →