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Verified by IngredientMD/NOW Foods/NOW Pantothenic Acid 500mg
VERIFIED BYingredientMD

NOW Pantothenic Acid 500mg.

Backed by human trialsNOW Foods, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by NOW Foods.

Calcium is the lead active here, studied most for bone strength. 13 human studies on Calcium back this formula, each one cited. Pantothenic Acid is here at a daily maintenance amount, which is what a daily supplement is for. Who it fits: skews toward women, adults.

Full label disclosure
2Active ingredientsWell studiedResearch base18Human studies
NOW Pantothenic Acid 500mgVerified by IngredientMD
NOW FoodsIngredientMD
The verdict
Backed by human trials
For Skews toward women, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Pantothenic Acid: Skin barrier supportWell studied
Calcium: Bone strengthKey driver

How we read this product

Source: Supplement facts
Supplement Facts panel for NOW Pantothenic Acid 500mg
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
18
Human studies
45 mg
Calcium
500 mg
Pantothenic Acid
500 mg per serving clears the studied 5 mg minimum
Pantothenic Acid, NIH ODS + Tahiliani 1991 review

Cross-checked against 1,295 documented interactions for these actives.

Read the evidencePantothenic Acid, the evidence →Calcium, the evidence →

Inside the formula

Pantothenic Acid
Skin barrier support
Well studied
Calcium
13 studies
Bone strength
Key driver
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
Daily usePublished 2024

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Pantothenic Acid

Randomised trial, 2014

An oral pantothenic acid supplement significantly lowered total facial blemish count versus placebo after 12 weeks, with fewer inflammatory blemishes.

Dermatology and Therapy
Pantothenic Acid

Randomised trial, 2021

Chronic pantothenic acid supplementation did not produce a detectable change in muscle coenzyme A content or cycling performance, which is a failure to detect a difference rather than a demonstration that none exists.

Applied Physiology, Nutrition, and Metabolism
2 more
Pantothenic Acid

Randomised trial, 2014

Pantethine, a vitamin B5 derivative, lowered LDL cholesterol by about 11 percent from baseline versus placebo over 16 weeks in adults at low to moderate cardiovascular risk.

Vascular Health and Risk Management
Pantothenic Acid

Randomised trial, 2015

Pantethine lowered blood triglycerides by about 17 percent from baseline over 8 weeks in adults with moderate dyslipidemia, while a related compound, coenzyme A, lowered them further.

Journal of Clinical Lipidology

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people13 human studies on Calcium back this formula, each one cited.
  • A mechanism that is settledHow Pantothenic Acid and Calcium work is settled pharmacology.
  • Recent work on the recordThe most recent study on this record was published in 2024.
  • A stated daily maintenance amountPantothenic Acid is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
  • The exact form, describedThe label names its forms exactly: Calcium D-pantothenate, Calcium carbonate. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madePantothenic Acid is made by synthetic.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Calciumwithin about one to six hours of a single doseMeasured within a day

    A randomised cross-over trial in ten women of mean age 69 gave a single 500 mg dose of calcium as citrate fasting, citrate with a meal, fortified juice or a dairy product meal, with blood drawn before and at 1, 2, 4 and 6 hours. Serum ionised and total calcium increased significantly from baseline over six hours, with the rise similar after fortified juice, delayed when citrate was taken with a meal and smaller after the dairy meal. A separate double-blind cross-over trial in 25 postmenopausal women measured parathyroid hormone and a bone resorption marker 12 hours after a single calcium dose. Ten participants is a small sample, and what moved was blood chemistry, not a sensation.

    Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

Two ingredients, from each one's own page.

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • D-pantothenic acid

    The free acid form of vitamin B5, an amide of pantoic acid and beta-alanine, supplied as a viscous hygroscopic oil or a stabilised liquid rather than a dry salt.

    Fits
    The un-neutralised acid carries no mineral counterion, so it suits liquid drops, syrups and formats where a calcium or sodium salt is not wanted.
    Trade-off
    It is hygroscopic and tends to draw water and turn sticky, which makes it awkward to hold as a dry powder without added stabilisers.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Best forMost standard doses, and anywhere a short, clean label is the point.

Questions shoppers ask

Is NOW Pantothenic Acid 500mg independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in NOW Pantothenic Acid 500mg?
NOW Pantothenic Acid 500mg is built on Pantothenic Acid, Calcium. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 1,295 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

Independent review by IngredientMD, not commissioned by NOW FoodsWork at NOW Foods? This verification is yours to claim →