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Verified by IngredientMD/Nutricost/Magnesium L-Threonate
VERIFIED BYingredientMD

Magnesium L-Threonate.

Backed by human trialsNutricost, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Nutricost.

Magnesium L-Threonate is the lead active here, studied most for memory and recall. Magnesium is the most studied active here, with 21 human studies behind it, each one cited. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
2Active ingredientsWell studiedResearch base28Human studies
Magnesium L-ThreonateVerified by IngredientMD
NutricostIngredientMD
The verdict
Backed by human trials
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Magnesium L-Threonate: Memory and recallKey driver
Magnesium: Focus and clear thinkingExtensively studied

How we read this product

Source: Supplement facts
Supplement Facts panel for Magnesium L-Threonate
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
28
Human studies
2000 mg
Magnesium L-Threonate
144 mg
Magnesium

Cross-checked against 456 documented interactions for these actives.

Read the evidenceMagnesium L-Threonate, the evidence →Magnesium, the evidence →

Inside the formula

Magnesium L-Threonate
Memory and recall
Key driver
Magnesium
21 studies
Focus and clear thinking
Extensively studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

The people it speaks toFieldwork 2011

12.7% of US adults aged 60 and over

in 21 states reported increased confusion or memory loss in the preceding 12 months, in the 2011 Behavioral Risk Factor Surveillance System.

CDC, MMWR Surveillance Summaries, 2015
This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
10 more
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Magnesium L-Threonate

Randomised trial, 2026

In 100 adults aged 18-45 with sleep complaints, 2 grams of magnesium L-threonate daily for 6 weeks improved cognition and reaction time, but tracked sleep showed no change.

Frontiers in Nutrition
Magnesium L-Threonate

Randomised trial, 2016

In adults aged 50 to 70 with memory concerns, 12 weeks of magnesium L-threonate raised an overall thinking score more than placebo.

The paper
Liu et al., 2016PMID 26519439
Magnesium L-Threonate

Randomised trial, 2022

In 109 healthy adults, a magnesium L-threonate formula for 30 days improved overall memory scores more than placebo, with bigger gains in older participants.

Nutrients
Magnesium L-Threonate

Randomised trial, 2024

In adults aged 35 to 55 with sleep problems, 1 gram of magnesium L-threonate daily for 21 days improved deep and REM sleep, energy and alertness versus placebo.

Sleep Medicine: X
Magnesium L-Threonate

Systematic review, 2024

Across 3 randomised trials and 12 cohorts, the trial evidence was too limited to judge magnesium supplements for cognition, while the cohorts, which show association only, pointed to a mid-range serum magnesium level of about 0.85 mmol/L tracking with better cognitive ageing.

Advances in Nutrition

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people21 human studies on Magnesium back this formula, each one cited.
  • A mechanism that is settledHow Magnesium L-Threonate and Magnesium work is settled pharmacology.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
  • The exact form, describedThe label names its forms exactly: Magnesium L-threonate powder, Magnesium oxide. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeMagnesium is made by mineral.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
General timing

How each ingredient usually behaves over time.

Two ingredients, from each one's own page.

  • Magnesium L-ThreonateAbout four weeks

    Give it about four weeks. Trials measured cognitive outcomes over eight to twelve weeks, so any change arrives gradually rather than on a particular day.

    Its own page, the plain answer on timing

  • Magnesium

    A looser stool can turn up the same day at the higher end. Sleep and cramp changes usually settle in across two to four weeks, because it is refilling a body-wide store.

    Its own page, the plain answer on timing

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • Magnesium L-threonate

    Magnesium bound to L-threonic acid, a metabolite of vitamin C.

    Fits
    cognition-positioned formulas, where the endpoints its trials measured are memory and reaction time rather than blood magnesium
    Trade-off
    the human trials run on one branded ingredient, the objective sleep measures from a wearable did not move, and a third positive cognition trial tested it inside a combination with phosphatidylserine and vitamins C and D, so the form is not isolated there

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Best forMost standard doses, and anywhere a short, clean label is the point.
From the same shelf

Studied alongside this brand's other formulas

Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.

Questions shoppers ask

Is Magnesium L-Threonate independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Magnesium L-Threonate?
Magnesium L-Threonate is built on Magnesium L-Threonate, Magnesium. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 456 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

Independent review by IngredientMD, not commissioned by NutricostWork at Nutricost? This verification is yours to claim →