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Verified by IngredientMD/Nutricost/Vitamin K2 MK-7
VERIFIED BYingredientMD

Vitamin K2 MK-7.

Strong evidence, strong doseNutricost, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Nutricost.

Vitamin K2 (as menaquinone-7) is the lead active here, studied most for filling everyday nutrient gaps. 13 human studies on Vitamin K2 (as menaquinone-7) back this formula, each one cited. Each serving carries 100 mcg of Vitamin K2 (as menaquinone-7), inside the range the published research used. Who it fits: skews toward women, adults.

Clinically dosedFull label disclosure
1Active ingredientWell studiedResearch base13Human studies
Vitamin K2 MK-7Verified by IngredientMD
NutricostIngredientMD
The verdict
Strong evidence, strong dose
For Skews toward women, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Vitamin K2 (as menaquinone-7): Filling everyday nutrient gapsKey driver

How we read this product

Source: Supplement facts
Supplement Facts panel for Vitamin K2 MK-7
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 1 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
13
Human studies
100 mcg
Vitamin K2 (as menaquinone-7)
100 mcg per serving sits inside the studied 45 mcg-100 mcg range
Vitamin K2 (as menaquinone-7), Knapen 2013 + Geleijnse 2004 Rotterdam study

Cross-checked against 1 documented interactions for these actives.

Read the evidenceVitamin K2 (as menaquinone-7), the evidence →

Inside the formula

Vitamin K2 (as menaquinone-7)
13 studies
Filling everyday nutrient gaps
Studied 45 mcg to 500 mcg a day
Key driver
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

The people it speaks toFieldwork 2019

12.3% of US adults

met the fruit intake recommendation and 10.0% the vegetable recommendation in 2019, in the Behavioral Risk Factor Surveillance System across 49 states.

CDC, MMWR, 2022
The people it speaks toFieldwork August 2021 to August 2023

60.2% of US adults aged 20 and over

took a dietary supplement in the past 30 days, and 38.7% took two or more, in the 2021 to 2023 National Health and Nutrition Examination Survey.

CDC National Center for Health Statistics, 2026
Daily usePublished 2024

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
7 more
Vitamin K2 (as menaquinone-7)

Meta-analysis, 2022

Across nine trials in postmenopausal women, vitamin K2 raised lumbar spine bone density by about 2.2 percent and forearm bone density by about 1.6 percent compared with control.

Journal of Bone and Mineral Metabolism
Vitamin K2 (as menaquinone-7)

Meta-analysis, 2025

Across six mostly observational studies in 2,327 Japanese adults, habitual natto intake linked to much higher blood MK-7 and modestly greater bone density, a food-intake association, not a measured effect.

Front Nutr
Vitamin K2 (as menaquinone-7)

Randomised trial, 2013

In healthy postmenopausal women, three years of 180 micrograms a day of MK-7 slowed bone density loss at the spine and hip, and improved bone strength.

The paper
Knapen et al., 2013PMID 23525894
Vitamin K2 (as menaquinone-7)

Randomised trial, 2020

In this trial of a low daily MK-7 amount, bone mineral density changed over the study period in the group given it, an imaging measurement, not a clinical event.

Calcified Tissue International
Vitamin K2 (as menaquinone-7)

Meta-analysis, 2025

In nine trials of 2,570 older women with low bone mass, vitamin K2 changed blood signals tied to bone turnover, not actual bone strength.

Front Endocrinol
Vitamin K2 (as menaquinone-7)

Systematic review, 2026

The authors report that effects on glycaemic measures differ across groups with differing baseline blood sugar status, so results are not uniform across populations. The outcomes assessed are blood markers.

Nutrients

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people13 human studies on Vitamin K2 (as menaquinone-7) back this formula, each one cited.
  • A mechanism that is settledHow Vitamin K2 (as menaquinone-7) works is settled pharmacology.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Serving amount inside the studied rangeEach serving carries 100 mcg of Vitamin K2 (as menaquinone-7), inside the range the published research used.
  • A stated daily maintenance amountVitamin K2 (as menaquinone-7) is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a softgel, so the active is already dissolved in oil and the shell keeps it away from air and light.
  • The exact form, describedThe form on the label is MK-7, all-trans menaquinone-7. The record says what that form is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeVitamin K2 (as menaquinone-7) is made by more than one route.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Vitamin K2 (as menaquinone-7)about four weeks of daily useBuilds with daily use

    A double-blind randomised dose-finding trial gave 60 postmenopausal women aged 50 to 69 either 0, 50, 100 or 200 micrograms of menaquinone-7 daily for four weeks on a controlled diet. The ratio of carboxylated to undercarboxylated osteocalcin rose dose dependently, with significant differences from the 0 microgram group at 100 and 200 micrograms. A companion 12-week trial in 120 people aged 20 to 69 confirmed the change at 100 micrograms daily. Both studies were run by authors affiliated with the R and D division of J-Oil Mills. An independent 8-week double-blind trial in 55 healthy prepubertal children found the same direction at 45 micrograms daily. What was measured is a blood marker of vitamin K status, not bone density and not a sensation.

    Promising
  • Vitamin K2 (as menaquinone-7)three years of daily use, with measurements at one, two and three yearsBuilds with daily use

    A double-blind randomised trial gave 244 healthy postmenopausal women either placebo or 180 micrograms of menaquinone-7 daily for three years, with bone mineral density measured by DXA at baseline and after each year. Menaquinone-7 decreased the age-related decline in bone mineral content and bone mineral density at the lumbar spine and femoral neck, but not at the total hip. The effect is a slowed decline rather than a gain, and the trial ran three years rather than weeks.

    Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

One ingredient, from its own page.

  • Vitamin K2 (as menaquinone-7)Days, not hours

    Days for absorption, weeks for the marker. Undercarboxylated osteocalcin falls across roughly four to twelve weeks of daily intake, and that is a status marker rather than an outcome.

    Its own page, the plain answer on timing

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • Menaquinone-7 (MK-7)

    The long-side-chain menaquinone, usually made by bacterial fermentation of the kind that gives natto its K2. The seven-unit tail keeps it circulating far longer than the short-chain MK-4, which is why microgram doses are the convention.

    Fits
    Formulas that want a once-daily microgram-level K2 with a fermentation-sourced supply chain.
    Trade-off
    Trial outcomes beyond raising K2 status take months to years to read out, and the muscle-recovery use tested recently showed nothing over placebo.

    In a 12-week double-blind randomised controlled trial, 71 healthy young and older adults took menaquinone-7 at 240 micrograms daily or placebo. Circulating MK-7 rose with supplementation, while recovery from a bout of muscle-damaging resistance exercise did not differ from placebo on strength, function, soreness or inflammatory markers.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Softgel

It is a softgel, so the active is already dissolved in oil and the shell keeps it away from air and light.

Best forFat-soluble actives and oils: vitamin D, vitamin E, omega-3, CoQ10.
From the same shelf

Studied alongside this brand's other formulas

Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.

Questions shoppers ask

Is Vitamin K2 MK-7 independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Vitamin K2 MK-7?
Vitamin K2 MK-7 is built on Vitamin K2 (as menaquinone-7). Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 1 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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