24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 2022Beta-(1,3)-(1,6)-glucans is the lead active here, studied most for a balanced gut microbiome. Organic Cordyceps (Cordyceps militaris) Mushroom extract is the most studied active here, with 7 human studies behind it, each one cited. Each serving carries 250 mg of Beta-(1,3)-(1,6)-glucans, inside the range the published research used. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Cross-checked against 70 documented interactions for these actives.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 202252% of US adults
believe common digestive symptoms such as bloating and abdominal pain are just a normal part of life, per a 2026 Harris Poll conducted for Oshi Health.
The Harris Poll for Oshi Health, 202657.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics58% of the recommended fiber intake
was reached on average by US consumers, who ate 8.1 grams of fiber per 1,000 calories in 2017 to 2018 versus the 14 grams recommended, per USDA Economic Research Service analysis of federal food consumption survey data.
USDA Economic Research Service, 202340% of US adults
aged 18 and over report they experience bloating at least a few times a month, with 5% saying they experience it daily, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202334% of US adults
aged 18 and over report they experience abdominal discomfort or pain at least a few times per month, with women about twice as likely as men to report it several times weekly, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202328% of US adults
aged 18 and over say that digestive issues impact the quality of their life, a share that rises to about a third among those aged 18 to 44, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202332% of US adults
say they actively try to consume probiotics, and among them 60% try to do so at least once a day, per a 2022 IFIC survey on gut health.
International Food Information Council, 202259 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Randomised trial, 2017
After three weeks of a cordyceps mushroom blend, time to exhaustion grew by about 70 seconds and peak oxygen use rose more than on placebo.
Journal of Dietary SupplementsRandomised trial, 2019
Eight weeks of a Cordyceps mycelium extract (Paecilomyces hepiali, a related species) raised natural killer cell activity by about 39 percent from baseline relative to placebo in healthy adults.
BMC Complementary and Alternative MedicineSystematic review, 2024
Human trials of barley and oat beta-glucan reported shifts in immune and inflammatory markers and in gut microbiota composition, with results varying by dose.
Current nutrition reportsRandomised trial, 2025
Yeast beta-glucan supplementation increased the measured antibody response following seasonal influenza vaccination compared with placebo.
Journal of dietary supplementsRandomised trial, 2015
In healthy Korean men, 1.5 g a day of Cordyceps militaris for four weeks increased natural killer cell activity and lymphocyte proliferation compared with placebo.
Journal of Medicinal FoodRandomised trial, 2026
Before hard cycling, a single 1 gram dose of cordyceps sped up reaction time afterward, about 964 versus 1034 milliseconds, and raised oxygen use at rest.
PLoS OneRandomised trial, 2026
After 12 weeks, a mushroom blend with cordyceps lowered fatigue and improved sleep scores versus placebo, though cordyceps' own share of the effect cannot be separated out.
Brain and BehaviorRandomised trial, 2024
In long-distance runners over 16 weeks of pre-season training, Cordyceps militaris mycelium extract raised serum ferritin and helped maintain hemoglobin and hematocrit relative to placebo.
NutrientsRandomised trial, 2026
Six weeks of baker's yeast beta-glucan produced a distinct pattern of immune cell gene expression compared with placebo.
International journal of molecular sciencesRandomised trial, 2026
Eight weeks of a yeast cell derived beta-glucan supplement shifted redox and immune response markers in the adults studied.
NutrientsPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Two ingredients, from each one's own page.
It shows up as a hard session feeling more manageable rather than as anything you notice the day you take it.
Nothing acute. Viscous cereal forms move a post-meal glucose curve within hours, while cholesterol and immune measures are tracked across four to twelve weeks.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
It is a capsule, so the amount per serving is fixed and travels without measuring.
Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.
Reishi fruiting body extract carries branched beta-1,3/1,6-glucan as a major cell wall constituent, the same structural class recognised by innate immune lectin receptors. Stacking a mushroom extract with a purified glucan means the glucan doses add, which formulators frequently miss when they read the two as separate actives. Total beta-glucan across the formula is the number worth checking.
Established cell wall chemistry: medicinal mushroom extracts are themselves beta-1,3/1,6-glucan sources.. No combination trial has tested this exact pairing.
Maitake supplies branched beta-1,3/1,6-glucan from its cell wall, structurally closer to yeast glucan than to the linear cereal type. Combining it with a purified glucan raises total intake of the branched class. Whether that produces more receptor engagement depends on particle size and solubility of each preparation, which differ widely between extracts.
Established cell wall chemistry.. No combination trial has tested this exact pairing.
Turkey tail extracts are characterised by protein-bound beta-glucan fractions, so a formula pairing them with a purified glucan is delivering two preparations of one structural class. The bound protein fraction changes solubility and is why extracts are standardised differently from cereal glucan. Read the combination as additive on total glucan rather than as two distinct actives.
Established cell wall chemistry.. No combination trial has tested this exact pairing.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.