L-Tyrosine is the lead active here, studied most for focus and clear thinking. 10 human studies on L-Tyrosine back this formula, each one cited. Each serving carries 500 mg of L-Tyrosine, inside the range the published research used. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 1 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Cross-checked against 493 documented interactions for these actives.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
25% of employed US adults
reported difficulty focusing at work in the past month, in the American Psychological Association's 2024 Work in America survey.
American Psychological Association and The Harris Poll, 202412.7% of US adults aged 60 and over
in 21 states reported increased confusion or memory loss in the preceding 12 months, in the 2011 Behavioral Risk Factor Surveillance System.
CDC, MMWR Surveillance Summaries, 201517% of US adults
reported trouble focusing over the past year, in a 2017 Ipsos poll of 1,008 adults.
Ipsos, 20177.4% of US adults
reported serious difficulty concentrating, remembering or making decisions in 2023, up from 5.3% in 2013, and among adults aged 18 to 39 the share nearly doubled, from 5.1% to 9.7%, in the Behavioral Risk Factor Surveillance System.
Neurology, 2025More than 1 in 4 US adults aged 50 to 73
regularly take a supplement for their brain health, rising to 36% of those over 74, and memory is the reason 71% give, in AARP's 2019 survey.
AARP, 201953% of US adults
say they spend too much time on their smartphone, about 7 in 10 of adults under 30, in a Pew Research Center survey of 9,750 adults in 2026.
Pew Research Center, 202659 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Controlled human trial, 1999
One hour after a 150 mg/kg dose, tyrosine held working-memory accuracy higher while participants juggled several tasks at once, compared with placebo, with no change on the simpler single-task version.
Pharmacology, Biochemistry, and BehaviorSystematic review, 2015
Across the human cognitive and behavioral trials, tyrosine reliably supported working memory and cognitive control during short-term demanding or stressful conditions, with little added benefit when neurotransmitter demand was not raised.
Journal of Psychiatric ResearchDouble-blind placebo-controlled crossover trial, 1989
During 4.5 hours of combined cold and low-oxygen exposure, a single 100 mg/kg dose of tyrosine reduced stress symptoms, low mood, and performance decline in the people who reacted most to the conditions.
Brain Research BulletinRandomised trial, 2026
In a crossover trial in 30 healthy men taking 0 to 4 g a day for 4 weeks, no dose-related changes appeared in blood, biochemical or electrolyte laboratory measures, and mild side effects were no more common than with placebo.
NutrientsRandomised trial, 2020
In 9 older and 9 young adults cooled for 90 minutes, 150 mg per kg of oral l-tyrosine more than doubled skin vessel narrowing in older adults and helped hold core temperature.
Medicine and Science in Sports and ExerciseRandomised controlled trial, 1999
Cadets taking 2 g of tyrosine daily through a week of demanding military training scored higher on memory and tracking tasks and showed lower systolic blood pressure than those on a calorie-matched control drink.
Brain Research BulletinPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
Two controlled crossover trials in cold-exposure stress measured working memory at a set interval after dosing. Eight men took 150 mg per kg of L-tyrosine two hours before a 30 minute delayed matching-to-sample task at 4 degrees Celsius. Matching accuracy at the longest delay returned to the level seen at 22 degrees Celsius. In 19 volunteers immersed twice for 90 minutes in roughly 10 degree water, a 150 mg per kg bar taken before each immersion raised correct responses on the same memory measure. Both were small trials in an induced-stress setting, and a later crossover trial under exercise heat stress in eight men found no cognitive change despite raised serum tyrosine.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
One ingredient, from its own page.
Within about an hour of a dose. It shows up most when you're stretched by short sleep, cold, noise or back-to-back pressure. On an easy day there's less for it to do.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
What each form is, and where it fits in a formula. Measured findings carry the study that reported them.
The unmodified crystalline amino acid, carrying no salt, ester, or acetyl group. The form produced by fermentation and used in most tyrosine research.
Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.
It is a capsule, so the amount per serving is fixed and travels without measuring.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
