St Johns Wort and Antidepressants
Complete guide to taking St Johns Wort with Antidepressants. Safety, timing, and what the research says.
St Johns Wort and Antidepressants have a significant interaction. Serious risk of serotonin syndrome - can be life-threatening
Bottom line: Do not combine - choose one or the other
How They Interact
Serious risk of serotonin syndrome - can be life-threatening
Timing
Do not combine - choose one or the other
What to do about it
Do not combine - choose one or the other
This is a clinically significant interaction. Consult your healthcare provider before combining these.
Evidence Sources
Common Questions
Taking St Johns Wort with Antidepressants requires caution. Serious risk of serotonin syndrome - can be life-threatening Do not combine - choose one or the other
Related Interactions
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Every ingredient page carries the interactions, cautions and timing behind entries like this one.
Browse the libraryMedical Disclaimer: This information is for educational purposes only and is not intended as medical advice. Always consult with a healthcare provider before making changes to your supplement regimen, especially if you take medications.