Purpose-built methylation support with every ingredient in its active coenzyme form. 5-MTHF folate at 1700mcg DFE far exceeds optimal (above 800mcg). Methylcobalamin B12 at 2000mcg is at the optimal-to-diminishing threshold. P5P (B6) at 45mg is well within therapeutic range. Riboflavin-5-phosphate at 25mg hits optimal. Betaine (TMG) at 750mg is 50% of optimal for methylation but provides meaningful methyl donor support. The synergy between these methylation cofactors is exceptional.
The set is generated, never written by the brand.
Thorne Methyl-Guard Plus: the formulation holds up. Lead: Folate at 1700 mcg DFE. Purpose-built methylation support with every ingredient in its active coenzyme form. Clinical dose on the primary, and the panel holds together.
The practitioner gold standard for methylation support. Every B-vitamin in its active coenzyme form. Betaine (TMG) provides methyl groups through an alternative pathway. Not a casual B-complex. This is targeted biochemistry for MTHFR and elevated homocysteine.
5 of 5 shown, 1 dose at what the trials used

