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Thorne, B_VITAMINS, analyzed by IngredientMD

Methyl-Guard Plus

5 ingredients documented, every dose read against the trials. The verdict set below is generated by the engine. Thorne can't edit it, and neither can we.

5 ingredients documentedRead line by line
Thorne Methyl-Guard Plus, front of pack
Front of pack, photograph on file
The verdict
Gold-standard dose.
For general wellness buyers.

Purpose-built methylation support with every ingredient in its active coenzyme form. 5-MTHF folate at 1700mcg DFE far exceeds optimal (above 800mcg). Methylcobalamin B12 at 2000mcg is at the optimal-to-diminishing threshold. P5P (B6) at 45mg is well within therapeutic range. Riboflavin-5-phosphate at 25mg hits optimal. Betaine (TMG) at 750mg is 50% of optimal for methylation but provides meaningful methyl donor support. The synergy between these methylation cofactors is exceptional.

Also earned
Dialed-inEvery B-vitamin in active coenzyme form (P-5-P, methylcobalamin, methylfolate, R-5-P).Betaine (TMG) provides an alternative methylation pathway.Specifically designed for MTHFR variants and elevated homocysteine.Thorne's practitioner-grade quality.

The set is generated, never written by the brand.

The read

Thorne Methyl-Guard Plus: the formulation holds up. Lead: Folate at 1700 mcg DFE. Purpose-built methylation support with every ingredient in its active coenzyme form. Clinical dose on the primary, and the panel holds together.

The practitioner gold standard for methylation support. Every B-vitamin in its active coenzyme form. Betaine (TMG) provides methyl groups through an alternative pathway. Not a casual B-complex. This is targeted biochemistry for MTHFR and elevated homocysteine.

Thorne Methyl-Guard Plus, front of packWhat's in this, per 45 servings
✓ dose matches what trials used
Folate5-MTHF L-Methylfolate1700 mcg DFE
Vitamin B12Methylcobalamin2000 mcg
Vitamin B6Pyridoxal-5-Phosphate45 mg
Vitamin B2Riboflavin-5-Phosphate25 mg
BetaineTrimethylglycine750 mg

5 of 5 shown, 1 dose at what the trials used

Capsules arranged in a tray
Behind every ingredient on this label
Read the evidence itself.

Every active in Methyl-Guard Plus has its own page: doses, forms, interactions, cautions, and the studies behind them.

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