35.1% of US adults
had at least one sunburn during the previous 12 months, in the 2024 National Health Interview Survey.
CDC National Center for Health Statistics, 2026Hydrolyzed Bovine Collagen (Types I & III) is the lead active here, studied most for skin hydration. Sodium is the most studied active here, with 11 human studies behind it, each one cited. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Cross-checked against 11 documented interactions for these actives.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
35.1% of US adults
had at least one sunburn during the previous 12 months, in the 2024 National Health Interview Survey.
CDC National Center for Health Statistics, 202650% of US adults
said they have a very or somewhat consistent skin care routine, in a YouGov survey fielded in April 2024.
YouGov, 202446% of US women
said they use moisturizer at least once a day, in a YouGov survey fielded in April 2024.
YouGov, 20249% of US women
said they would spend more than $60 on a single skin care product, in a YouGov survey fielded in April 2024.
YouGov, 202457.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics29.0% of US women
aged 18 and older said they always use sunscreen when outside for more than one hour on a sunny day, in the 2020 National Health Interview Survey.
CDC National Center for Health Statistics, 202259 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Systematic review and meta-analysis, 2021
Pooling 19 trials in 1,125 people, oral hydrolyzed collagen improved skin hydration and elasticity and reduced wrinkles versus placebo, with effects seen by about 90 days.
International Journal of DermatologyRandomised trial, 2008
Collagen at 10 g a day lowered walking joint pain by about 1.1 points versus 0.5 on placebo over 24 weeks in active athletes.
Current Medical Research and OpinionMeta-analysis, 2023
Pooling randomised trials of oral collagen, reviewers found improvements in skin hydration and elasticity compared with placebo.
NutrientsRandomised trial, 2018
Postmenopausal women taking 5 g of collagen peptides daily for 12 months gained bone density at the spine and hip, while it edged down on placebo.
NutrientsRandomised trial, 2025
In a placebo-controlled trial, bioactive collagen peptides were associated with improved skin measures that persisted for a period after intake stopped.
Journal of cosmetic dermatologyRandomised trial, 2026
Compared combined beta-alanine plus sodium bicarbonate against each alone on physical capacity measures in trained participants. The design is what makes the comparison informative for stacking decisions.
International Journal of Sports Physiology and PerformanceRandomised trial, 2025
In adults with knee discomfort, a combination supplement containing type I and type III collagen peptides alongside hydrolysed type II collagen was associated with lower reported pain and better joint function than control, so the effect cannot be attributed to type I and III alone.
BMC musculoskeletal disordersRandomised trial, 2026
Microencapsulated sodium butyrate was tested against abdominal symptom scores and carbohydrate metabolism markers in adults with high blood sugar. Again a butyrate trial in which sodium is the carrier salt.
Scientific ReportsRandomised trial, 2020
In a controlled dietary intervention in adults, changing sodium and potassium intake shifted how the body handled calcium and phosphate, indicating that sodium intake affects normal mineral balance.
The Journal of Clinical Endocrinology and MetabolismSystematic review, 2026
A systematic review catalogued gastrointestinal symptoms reported across sodium bicarbonate dosing protocols and described how symptom burden varies with dose, timing and whether the dose is split or given with food.
European Journal of Sport ScienceRandomised trial, 2026
A randomised trial tested an algorithm-driven sodium supplementation protocol against usual care and measured growth in infants born preterm.
Pediatrics Open ScienceRandomised trial, 2025
In a trial of 104 very preterm infants, oral sodium supplementation raised daily weight gain by 3.6 grams per kilogram compared with placebo.
BMJ Paediatrics OpenPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
In the excretion studies the EFSA reference opinion reviews, urinary output closely tracked dietary sodium once intake was held steady: 98% of dietary sodium appeared in 24-hour urine in a 3-day study, and 86% of sodium ingested over 4 weeks was recovered in 24-hour urine collected during the same period.
In the controlled metabolic study the EFSA reference opinion reviews, young men held at constant sodium intakes for 29 days per level showed rising average daily urinary aldosterone excretion as intake was stepped down from 4.9 g/day to 2.5 g/day.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
Two ingredients, from each one's own page.
Fast. Sodium shifts fluid within an hour or two, which is why an electrolyte drink lands quickly when you have been sweating.
Skin and nail studies usually read out at eight to twelve weeks, joint comfort around twelve. It's a slow build you see in photos rather than on one morning.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
It is a powder, so the serving scales to the amount you want and mixes into something you already drink.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.