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Verified by IngredientMD/NativePath/Collagen Peptides
VERIFIED BYingredientMD

Collagen Peptides.

Backed by human trialsNativePath, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by NativePath.

Hydrolyzed Bovine Collagen (Types I & III) is the lead active here, studied most for skin hydration. Sodium is the most studied active here, with 11 human studies behind it, each one cited. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
2Active ingredients17Human studies10 gHydrolyzed Bovine Collagen (Types I & III)
Collagen PeptidesVerified by IngredientMD
NativePathIngredientMD
The verdict
Backed by human trials
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Sodium: HydrationWell studied
Hydrolyzed Bovine Collagen (Types I & III): Skin hydrationKey driver

How we read this product

Source: Supplement facts
Supplement Facts panel for Collagen Peptides
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 2 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

17
Human studies
10 g
Hydrolyzed Bovine Collagen (Types I & III)
50 mg
Sodium
10 g per serving sits inside the studied 2.5 g-10 g range
Hydrolyzed Bovine Collagen (Types I & III), Choi 2019 meta-analysis + Zague 2011 skin studies

Cross-checked against 11 documented interactions for these actives.

Read the evidenceSodium, the evidence →Hydrolyzed Bovine Collagen (Types I & III), the evidence →

Inside the formula

Sodium
11 studies
Hydration
Well studied
Hydrolyzed Bovine Collagen (Types I & III)
Skin hydration
Key driver
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
14 more
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Hydrolyzed Bovine Collagen (Types I & III)

Systematic review and meta-analysis, 2021

Pooling 19 trials in 1,125 people, oral hydrolyzed collagen improved skin hydration and elasticity and reduced wrinkles versus placebo, with effects seen by about 90 days.

International Journal of Dermatology
Hydrolyzed Bovine Collagen (Types I & III)

Randomised trial, 2008

Collagen at 10 g a day lowered walking joint pain by about 1.1 points versus 0.5 on placebo over 24 weeks in active athletes.

Current Medical Research and Opinion
Hydrolyzed Bovine Collagen (Types I & III)

Meta-analysis, 2023

Pooling randomised trials of oral collagen, reviewers found improvements in skin hydration and elasticity compared with placebo.

Nutrients
Hydrolyzed Bovine Collagen (Types I & III)

Randomised trial, 2018

Postmenopausal women taking 5 g of collagen peptides daily for 12 months gained bone density at the spine and hip, while it edged down on placebo.

Nutrients
Hydrolyzed Bovine Collagen (Types I & III)

Randomised trial, 2025

In a placebo-controlled trial, bioactive collagen peptides were associated with improved skin measures that persisted for a period after intake stopped.

Journal of cosmetic dermatology
Hydrolyzed Bovine Collagen (Types I & III)

Randomised trial, 2025

In adults with knee discomfort, a combination supplement containing type I and type III collagen peptides alongside hydrolysed type II collagen was associated with lower reported pain and better joint function than control, so the effect cannot be attributed to type I and III alone.

BMC musculoskeletal disorders
Sodium

Randomised trial, 2026

Microencapsulated sodium butyrate was tested against abdominal symptom scores and carbohydrate metabolism markers in adults with high blood sugar. Again a butyrate trial in which sodium is the carrier salt.

Scientific Reports
Sodium

Systematic review, 2026

A systematic review catalogued gastrointestinal symptoms reported across sodium bicarbonate dosing protocols and described how symptom burden varies with dose, timing and whether the dose is split or given with food.

European Journal of Sport Science
Sodium

Randomised trial, 2026

A randomised trial tested an algorithm-driven sodium supplementation protocol against usual care and measured growth in infants born preterm.

Pediatrics Open Science
Sodium

Randomised trial, 2025

In a trial of 104 very preterm infants, oral sodium supplementation raised daily weight gain by 3.6 grams per kilogram compared with placebo.

BMJ Paediatrics Open

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people11 human studies on Sodium back this formula, each one cited.
  • A mechanism that is settledHow Sodium and Hydrolyzed Bovine Collagen (Types I & III) work is settled pharmacology.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
  • The exact form, describedThe label names its forms exactly: Sodium chloride, table salt, sea salt, Bovine collagen peptides, type I and III. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeSodium is made by mineral.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Sodiumabout 3 days to 4 weeks of steady intakeBuilds with daily use

    In the excretion studies the EFSA reference opinion reviews, urinary output closely tracked dietary sodium once intake was held steady: 98% of dietary sodium appeared in 24-hour urine in a 3-day study, and 86% of sodium ingested over 4 weeks was recovered in 24-hour urine collected during the same period.

    Early
  • Sodiumabout 29 days at each fixed intake levelBuilds with daily use

    In the controlled metabolic study the EFSA reference opinion reviews, young men held at constant sodium intakes for 29 days per level showed rising average daily urinary aldosterone excretion as intake was stepped down from 4.9 g/day to 2.5 g/day.

    Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

Two ingredients, from each one's own page.

  • Sodium

    Fast. Sodium shifts fluid within an hour or two, which is why an electrolyte drink lands quickly when you have been sweating.

    Its own page, the plain answer on timing

  • Hydrolyzed Bovine Collagen (Types I & III)About eight to twelve weeks

    Skin and nail studies usually read out at eight to twelve weeks, joint comfort around twelve. It's a slow build you see in photos rather than on one morning.

    Its own page, the plain answer on timing

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Format

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.

Best forGram-scale actives: creatine, collagen, protein, electrolytes, beta-alanine.

Questions shoppers ask

Is Collagen Peptides independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Collagen Peptides?
Collagen Peptides is built on Sodium, Hydrolyzed Bovine Collagen (Types I & III). Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 11 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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