KSM-66 Ashwagandha.

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

• Studied in people21 human studies on KSM-66 Ashwagandha Extract back this formula, each one cited.
• A mechanism that is settledHow KSM-66 Ashwagandha Extract and AstraGin work is settled pharmacology.
• Recent work on the recordThe most recent study on this record was published in 2026.
• Serving amount inside the studied rangeEach serving carries 300 mg of KSM-66 Ashwagandha Extract, inside the range the published research used.
• A stated daily maintenance amountKSM-66 Ashwagandha Extract is here at a daily maintenance amount, which is what a daily supplement is for.
• Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
• The exact form, describedThe label names its forms exactly: Milled ashwagandha root powder, AstraGin. The record says what each one is and what it suits.
• Full label disclosureEvery ingredient on this label carries its own declared amount.
• Where it comes from and how it is madeKSM-66 Ashwagandha Extract is made by botanical.
• Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
• A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

• KSM-66 Ashwagandha Extractabout eight to nine weeks of daily useBuilds with daily use

  In a 60 day randomised, double-blind, placebo-controlled trial, 60 stressed healthy adults took 240 mg of a standardised ashwagandha extract (Shoden) once daily or placebo. The ashwagandha arm showed a larger fall in Hamilton Anxiety Rating Scale scores (p = .040) and in morning cortisol (p < .001) than placebo, with the DASS-21 change near-significant (p = .096). A separate 8 week randomised, double-blind, placebo-controlled dose-ranging trial enrolled 131 adults with self-reported high stress and analysed 98, measuring reduced Perceived Stress Scale scores at 125, 250 and 500 mg per day of an aqueous root and leaf extract. Two trials on two different extracts, both landing in the same eight to nine week band.

  Lopresti et al., 2019 (Medicine)PMID 31517876

  Pandit et al., 2024 (Nutrients)PMID 38732539

  Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

How each ingredient usually behaves over time.

Two ingredients, from each one's own page.

• KSM-66 Ashwagandha ExtractAbout two to four weeks

  Give it two to four weeks. Morning cortisol shifts on a blood draw before a calmer week is something you'd describe out loud.

  Its own page, the plain answer on timing ↗

• AstraGin

  There is no timeline of its own to give. It acts on the absorption of whatever it sits beside, so any change follows that other ingredient's own timeline.

  Its own page, the plain answer on timing ↗

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

• Standardised root extract

  An extract of the root alone, standardised to its withanolide content, the constituent family the clinical literature doses by. Root-only sourcing distinguishes it from root-plus-leaf extracts.

  Fits

  Formulas that want the dosing and safety record of the studied preparations, since most trials used standardised root-only extracts at 125 to 600 mg a day.

  Trade-off

  Standardisation states withanolide content, not which withanolides. Extracts differ in their glycoside profile even at the same declared percentage.

  A systematic review of 23 randomised trials in 2,317 generally healthy adults taking standardised ashwagandha root extract at 125 to 600 mg per day, from a single dose to 180 days, found hepatic, renal, haematological, endocrine and cardiovascular biomarkers stayed within normal clinical ranges, reductions in cortisol were consistently observed, testosterone shifts stayed within physiological range, and no serious adverse events were attributed to the extract.

  Coope et al., 2026 (Pharmaceuticals)PMID 42198398
• AstraGinFormulation aid

  Fine off-white to tan powder, water dispersible, carrying triterpene saponins from both roots. The manufacturer standardises to its own internal marker profile rather than a publicly named compound.

  Fits

  Powders, capsules and tablets where the formulator wants a fixed, repeatable material at a low inclusion rate.

  Trade-off

  The composition and marker set are held as proprietary, so an independent laboratory cannot assay a batch against a published specification or compare two lots.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Studied alongside this brand's other formulas

Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.