The people it speaks toFieldwork 2024
Nearly 3 in 4 US adults
felt very tired or exhausted at least some days in the past three months, in the 2024 National Health Interview Survey.
CDC National Center for Health Statistics, 2026NOW Resveratrol 200mg
NOW Resveratrol 200mg.
Backed by human trials
trans-Resveratrol is the lead active here, studied most for ageing well. 10 human studies on trans-Resveratrol back this formula, each one cited. Who it fits: for everyone, adults.
Clinically dosedFull label disclosure
3Active ingredients29Human studies200 mgtrans-Resveratrol
Verified by IngredientMDHow we read this product
- 01We read the label.
The panel on the left is the one we evaluated, line by line.
- 02Every active, separately.
All 3 actives checked against the clinical evidence: dose, form, and what the research actually shows.
- 03Then the formula as a whole.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Backed by human trials".
- 04Earned, not bought.
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
The receipts
29
Human studies
200 mg
trans-Resveratrol
400 mg
Japanese Knotweed Extract Complex
10 mg
Grape Seed Extract
200 mg per serving sits inside the studied 150 mg-500 mg range
trans-Resveratrol, Timmers 2011 + Bhatt 2012 metabolic studies
Cross-checked against 15 documented interactions for these actives.
Inside the formula
In context
The gap this formula speaks to.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
The people it speaks toFieldwork 2022
13.9% of US adults aged 65 and over
met the federal physical activity guidelines for both aerobic and muscle-strengthening activity in 2022, in the National Health Interview Survey.
CDC National Center for Health Statistics, 2024The people it speaks toFieldwork 2024
75% of US adults aged 50 and over
want to stay in their own home as they age, and 73% in their community, in AARP's 2024 survey.
AARP, 2024The people it speaks toFieldwork 2019
54% of US adults aged 60 and over
say they worry about losing their independence, in a 2019 national survey of older Americans.
Ipsos and the National Council on Aging, 2019The people it speaks toFieldwork 2019
57% of older US adults
, aged 60 and over, rank staying active with their interests and activities among their top priorities, in a 2019 national survey of older Americans.
Ipsos and the National Council on Aging, 2019The people it speaks toFieldwork 2019
64% of US adults aged 60 and over
report being very or somewhat worried about their physical health, in a 2019 national survey of older Americans.
Ipsos and the National Council on Aging, 201911 more
30.5% of US adults
slept less than 7 hours on average in a 24-hour period in 2024, in the National Health Interview Survey.
CDC National Center for Health Statistics, 202657.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Systematic review, 2025
Pooled trials in older women reported modest improvements in bone mineral density and some cardiometabolic markers with resveratrol supplementation.
Frontiers in pharmacologyWu et al., 2025 (Frontiers in pharmacology)PMID 40771919
Randomised trial, 2025
In healthy women over 40, eight weeks of trans-resveratrol reduced visible signs of skin ageing such as wrinkle appearance compared with placebo.
Frontiers in agingRao et al., 2025 (Frontiers in aging)PMID 41488277
Systematic review, 2026
The review pooled the human literature on anthocyanins, curcumin and resveratrol and reports effects on metabolic measures that vary by compound, dose and study duration.
MoleculesGazda et al., 2026 (Molecules)PMID 42280140
Systematic review, 2025
The systematic review of resveratrol supplementation for retinal endpoints found the supporting work is largely preclinical and calls the human evidence base limited.
Frontiers in PharmacologyLv et al., 2025 (Frontiers in Pharmacology)PMID 40717982
Randomised trial, 2017
Trans-resveratrol did not detectably change endothelial function in the fasting state or after a meal compared with placebo.
Nutrientsvan der Made et al., 2017 (Nutrients)PMID 28604618
Systematic review, 2024
The review of resveratrol and female fertility reports mechanistic and animal support with human data that the authors describe as heterogeneous and insufficient for firm conclusions.
International Journal of Molecular SciencesMeta-analysis, 2020
Pooling randomised trials of resveratrol, the stilbene that Japanese knotweed extracts are standardised to, the analysis did not detect a clear difference in liver enzyme readings or liver fat in adults with elevated liver fat, which is a failure to find an effect rather than evidence that none exists.
NutrientsJakubczyk et al., 2020 (Nutrients)PMID 32823621
Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Every one of these is a fact the engine could ground.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
- Studied in people17 human studies on Grape Seed Extract back this formula, each one cited.
- A mechanism that is settledHow Japanese Knotweed Extract Complex and trans-Resveratrol work is settled pharmacology.
- Studied together, not just separatelyJapanese Knotweed Extract Complex and Grape Seed Extract have been studied together, not only separately.
- Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
- The exact form, describedThe label names its forms exactly: Whole root powder (Hu Zhang), Polygonum cuspidatum root extract, standardised, Grape seed extract standardised to 95 percent proanthocyanidins. The record says what each one is and what it suits.
- Full label disclosureEvery ingredient on this label carries its own declared amount.
- Where it comes from and how it is madetrans-Resveratrol is made by more than one route.
- Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
- A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
How each ingredient usually behaves over time.
Three ingredients, from each one's own page.
- Japanese Knotweed Extract ComplexAbout four to eight weeks
Plan on four to eight weeks of daily use. The trials that found something read it off vascular and metabolic measures rather than off how people said they felt.
- trans-ResveratrolAbout eight to twelve weeks
Give it eight to twelve weeks. What changes shows up in blood markers such as lipids and glucose handling rather than in how an afternoon feels.
- Grape Seed ExtractWithin hours
Blood flow measures shift within hours of a dose in trial settings. What shows on a home cuff builds over four to eight weeks of daily use.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
Capsule
It is a capsule, so the amount per serving is fixed and travels without measuring.
Best forMost standard doses, and anywhere a short, clean label is the point.
Questions shoppers ask
- Is NOW Resveratrol 200mg independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in NOW Resveratrol 200mg?
- NOW Resveratrol 200mg is built on Japanese Knotweed Extract Complex, trans-Resveratrol, Grape Seed Extract. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against 15 documented interactions for these actives in IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
Independent review by IngredientMD, not commissioned by NOW FoodsWork at NOW Foods? This verification is yours to claim →