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Verified by IngredientMD/TB12/Protect Immunity Supplement
VERIFIED BYingredientMD

Protect Immunity Supplement.

Strong evidence, strong doseTB12, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by TB12.

Elderberry Fruit Powder is the lead active here, studied most for immune resilience. Zinc is the most studied active here, with 22 human studies behind it, each one cited. Each serving carries 11 mg of Zinc, inside the range the published research used. Who it fits: for everyone, adults.

Full label disclosure
5Active ingredientsWell studiedResearch base58Human studies
Protect Immunity SupplementVerified by IngredientMD
TB12IngredientMD
The verdict
Strong evidence, strong dose
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Vitamin C: Immune resilienceExtensively studied
Zinc: Immune resilienceExtensively studied
Larch Extract: Immune resilienceWell studied
Elderberry Fruit Powder: Immune resilienceKey driver
Yeast Beta Glucan: The immune barrier in the nose and throatWell studied

How we read this product

Source: Supplement facts
Supplement Facts panel for Protect Immunity Supplement
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 5 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
58
Human studies
350 mg
Elderberry Fruit Powder
120 mg
Vitamin C
11 mg per serving sits inside the studied 8 mg-15 mg range
Zinc, NIH ODS + Prasad 2008 zinc review
350 mg per serving sits inside the studied 175 mg-600 mg range
Elderberry Fruit Powder, Hawkins 2019 meta + Tiralongo 2016 cold study
250 mg per serving sits inside the studied 100 mg-250 mg range
Yeast Beta Glucan, Saeed et al. 2021 Nutrients review; Bashir & Choi 2017 Int J Mol Sci.

Cross-checked against 940 documented interactions for these actives.

Read the evidenceVitamin C, the evidence →Zinc, the evidence →Larch Extract, the evidence →Elderberry Fruit Powder, the evidence →Yeast Beta Glucan, the evidence →

Inside the formula

Vitamin C
20 studies
Immune resilience
Extensively studied
Zinc
22 studies
Immune resilience
Studied 8 mg to 30 mg a day
Extensively studied
Larch Extract
Immune resilience
Well studied
Elderberry Fruit Powder
Immune resilience
Studied 175 mg to 1.2 g a day
Key driver
Yeast Beta Glucan
The immune barrier in the nose and throat
Well studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
The people it speaks toFieldwork August 7 to 12, 2024

30% of US supplement users

name immune health as a reason they take a supplement, second only to general health and wellness, in the Council for Responsible Nutrition's 2024 Consumer Survey.

Council for Responsible Nutrition, 2024
27 more
The people it speaks to

48% of US adults

admit they forget or choose not to wash their hands at key moments, and one in five say they actively choose not to, in the 2025 State of Handwashing Report.

National Foundation for Infectious Diseases, 2025
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Larch Extract

Randomised trial, 2013

In a multidose placebo-controlled study, larch arabinogalactan altered blood immune cell and cytokine measures in healthy adults, with the response differing by dose.

Journal of the American College of Nutrition
Yeast Beta Glucan

Randomised trial, 2026

Daily baker's yeast beta-1,3/1,6-glucan raised markers of mucosal immune activity in the upper airway of healthy adults compared with placebo.

Nutrients
Elderberry Fruit Powder

Systematic review, 2021

The authors pooled the available elderberry trials for upper respiratory symptoms and concluded the evidence is limited, the trials small and the certainty low, with some reporting shorter symptom duration.

BMC Complementary Medicine and Therapies
Larch Extract

Randomised trial, 2010

A proprietary arabinogalactan extract raised the measured antibody response to a pneumococcal vaccine compared with placebo in healthy adults.

Nutrition journal
Yeast Beta Glucan

Randomised trial, 2013

Beta-glucan from baker's yeast raised salivary IgA, an antibody in saliva, and lowered reported symptom days in adults after a hard exercise bout.

Journal of dietary supplements
Yeast Beta Glucan

Randomised trial, 2013

Taking baker's yeast beta-glucan was followed by higher immune cell counts and signaling markers in the blood after exercise, which are lab markers, not health outcomes.

British Journal of Nutrition
Larch Extract

Randomised trial, 2013

The authors reported fewer self-reported episodes of upper respiratory symptoms in the larch arabinogalactan group than in placebo over the supplementation period.

Current medical research and opinion
Elderberry Fruit Powder

Randomised trial, 2016

The authors reported shorter symptom duration and lower symptom scores in the elderberry arm compared with placebo among long-haul air travellers.

Nutrients
Elderberry Fruit Powder

Randomised trial, 2025

In ten adults with excess weight, a week of twice-daily elderberry juice shifted activity in 234 genes versus 59 on placebo, a gene-activity signal rather than a measured outcome.

Nutrients
Elderberry Fruit Powder

Randomised trial, 2020

In this double-blind placebo-controlled trial the investigators did not detect a difference in symptom duration between elderberry extract and placebo. A failure to detect a difference is not a demonstration that none exists.

Journal of General Internal Medicine
Zinc

Meta-analysis, 2024

Across six trials in 739 women, zinc lowered menstrual discomfort scores, with bigger drops after eight weeks or more, even at doses as low as 7 mg daily.

Nutrients
Zinc

Meta-analysis, 2025

Across four trials in women of reproductive age, zinc lowered premenstrual symptom scores, with the biggest gain in mood and a smaller, less certain gain in physical symptoms.

Women and Health
Yeast Beta Glucan

Randomised trial, 2024

Yeast beta-glucan supplementation lowered insulin resistance readings, a blood marker, without changing the make-up of the gut bacteria.

The British journal of nutrition
Elderberry Fruit Powder

Randomised trial, 2024

In a crossover trial of 18 overweight adults, one week of elderberry juice lowered post-meal blood glucose and raised fat oxidation during and after a meal test.

Nutrients
Zinc

Meta-analysis, 2026

Pooling randomised trials in adults, zinc had a small effect on body weight and waist circumference and no detectable effect on body mass index, fat mass, fat-free mass or adipokine levels, and the authors call the size of the changes minor.

Biological Trace Element Research
Zinc

Meta-analysis, 2011

Across 36 studies in children under five, zinc modestly increased height growth, adding roughly 0.37 cm at about 10 mg a day for 24 weeks.

BMC Public Health

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people22 human studies on Zinc back this formula, each one cited.
  • A mechanism that is settledHow Vitamin C and Zinc work is settled pharmacology.
  • Studied together, not just separatelyVitamin C and Zinc have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2025.
  • Serving amount inside the studied rangeEach serving carries 11 mg of Zinc, inside the range the published research used.
  • A stated daily maintenance amountZinc is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeVitamin C is made by fermentation.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Vitamin Cwithin 24 hours of a single doseMeasured within a day

    In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

    Strong
  • Zincover about five days of lozenges started within 24 hours of symptom onsetBuilds with daily use

    Across three randomised placebo-controlled trials pooled as individual patient data (199 adults with naturally acquired colds, 80 to 92 mg of elemental zinc a day as acetate lozenges), 70 percent of the zinc group had recovered by day 5 against 27 percent on placebo, and colds ran 2.73 days shorter against a 7 day average duration. A separate meta-analysis of seven lozenge trials (575 participants, doses above 75 mg a day, zinc acetate or zinc gluconate) measured cold duration 33 percent shorter, with no significant difference between the two salts.

    Strong
  • Zincabout two to four weeks of daily intakeBuilds with daily use

    In a controlled feeding study in nine healthy men, six weeks of restricted zinc intake raised DNA strand breaks in peripheral blood cells, and four weeks of repletion at 11 mg a day, with 20 mg of supplemental zinc for the first seven days, reversed the rise. In a separate randomised placebo-controlled trial in 40 Ethiopian women eating a high-phytate diet, 20 mg a day of zinc sulfate for 17 days lowered mean comet tail moment from 39.7 to 30.0 while plasma zinc did not change significantly. Both windows were measured on a DNA damage marker in blood cells, not on a symptom.

    Early
  • Elderberry Fruit Powderwithin about 7 hours of a single doseMeasured within a day

    In a kinetic study, 6 healthy volunteers took a single 30 ml oral dose of elderberry extract providing 147.3 mg of anthocyanins. The anthocyanins appeared in plasma and were excreted in urine within 7 hours, with a plasma half-life of about 1.74 hours.

    Strong
  • Elderberry Fruit Powderabout 1 week of twice-daily useBuilds with daily use

    In a randomised crossover trial, adults with overweight consumed anthocyanin-rich elderberry juice twice daily for 1 week. After that week, gut microbiota composition had shifted, post-meal blood glucose was lower and fat oxidation was higher than after placebo.

    Early

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

Five ingredients, from each one's own page.

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Format

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Best forMost standard doses, and anywhere a short, clean label is the point.
Recurring supply suggested

Because the effect builds and holds only with continued daily use, a steady recurring supply is the practical way to keep it going.

Questions shoppers ask

Is Protect Immunity Supplement independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Protect Immunity Supplement?
Protect Immunity Supplement is built on Vitamin C, Zinc, Larch Extract, Elderberry Fruit Powder, Yeast Beta Glucan. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 940 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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