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Ingredients/Tcm/Angelica Dahurica Root

Angelica Dahurica Root.

Strength pending.The research strength is not set yet.

Angelica Dahurica Root supplementation for targeted health support. Clears nasal congestion, relieves headaches and facial pain, reduces swelling. Traditional 'wind-expelling' herb for the head region.

3 to 9gDaily amount78Studies read

Reviewed March 2026

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Angelica Dahurica RootIngredientMD
Category
Tcm

What Angelica Dahurica Root is, and what it does.

Does it work
Good traditional herb for sinus and headache issues. Limited modern research but strong traditional evidence.
How much to take
3-10g dried root in decoction, or 500-1500mg extract daily.
Time to feel it
Traditional use is short, over a day or two rather than weeks. None of the 78 records at Europe PMC times an onset, so the traditional pattern is the only guide on record.
The first dose
May notice sinus clearing or headache relief fairly quickly.
With regular use
Traditional use for recurring sinus issues and headaches.
How well tolerated
Photosensitizing. Avoid sun after use. Not for pregnancy. Generally well tolerated otherwise.
How it feels
Opening sensation in sinuses. Possible headache relief. More noticeable than some TCM herbs.
The overlooked benefit
Its furanocoumarins slow the CYP3A4 enzyme in the gut wall the way grapefruit constituents do, and the effect outlasts the herb, so spacing doses apart does not undo it.

3 to 9g a day is where Angelica Dahurica Root works.

How much to take a dayLimited data
3 to 9g
Daily maintenanceThe everyday amount, and where most daily supplements sit. This is the one you take month after month.
15gClinical territory. Trials run high on purpose, for a set number of weeks, against one measured outcome. Impressive to hit, and not what a daily product is for.
Above 20gPast what the research covers. More capsules rather than more effect.
MORE EFFECT ↑09g15g plateauDAILY DOSE →
The shaded band is where the dosing trials landed.

Source: Chinese Pharmacopoeia; Bai Zhi TCM monographs

The proof, claim by claim.

These words describe the research, not the molecule's worth. Research strength is how much work stands behind one claim, and it is never a product score.

Angelica Dahurica Root has emerging evidence. Based on 78+ studies.

  • Clears nasal congestionTraditional use and limited modern studies
  • Relieves headachesTraditional use and analgesic compound research
  • Anti-inflammatory effectsCoumarin research
  • Causes photosensitivityFuranocoumarin content well-documented
PubMedCochraneClinicalTrials.govNIH ODSSUPP.AI78 studies readLabs test. IngredientMD verifies.PubMedCochraneClinicalTrials.govNIH ODSSUPP.AI78 studies readLabs test. IngredientMD verifies.

Questions people ask about Angelica Dahurica Root.

What does Bai Zhi mean?
'White Angelica.' The name refers to the white color of the dried root and distinguishes it from other Angelica species.
Why avoid sun?
Contains furanocoumarins that cause photosensitivity. You can get severe sunburn after internal use. Avoid strong sun for 12-24 hours.
Is it good for migraines?
Traditional use for 'yang ming' headaches (forehead, sinus area). May help certain headache types, especially sinus-related.
Is it related to Dong Quai?
Both are Angelica species but different. Dong Quai (A. sinensis) is used for blood and women's health. Bai Zhi is for head and sinus issues.
Can I use it for colds?
Traditional use at early stages of wind-cold. For sinus congestion and headache during colds. Often combined with other herbs.
What are the coumarins doing?
Anti-inflammatory, analgesic, and some antimicrobial effects. Also responsible for the photosensitivity.
Pairs well with10 on file

Why these belong in the same formula. Each row says what the basis is, from settled biochemistry through to a trial that measured the pair.

Angelica Dahurica Root + Black Pepper Extract (BioPerine)established pharmacology of each component, not measured together

Linear furanocoumarins from Angelica dahurica root are mechanism-based inhibitors of intestinal CYP3A4. Piperine inhibits the same enzyme and also slows P-glycoprotein efflux. Taken together they push in the same direction, so exposure to anything else in the formula that is cleared by CYP3A4 can run higher than either would produce alone. This is reasoning from each ingredient's known pharmacology, not a measured combination.

Angelica Dahurica Root + Dang Guishared plant chemistry within the Angelica genus

Both roots come from the Angelica genus and both carry coumarin and furanocoumarin fractions. Stacking two coumarin-rich roots adds to the total furanocoumarin load, which is the fraction behind increased skin sensitivity to ultraviolet light. The two are also long-standing companions in traditional formula design. The additive part is chemistry, not a trial.

Angelica Dahurica Root + St Johns Wortestablished pharmacology of each component, opposite directions

St John's wort induces CYP3A4 over days of use while Angelica dahurica furanocoumarins inhibit it acutely, so the two pull the same enzyme in opposite directions and the net effect on anything else in the formula becomes unpredictable. Separately, hypericin is itself photosensitising, so the skin-sensitivity side of the pair is additive rather than opposing. Both halves are textbook pharmacology.

Angelica Dahurica Root + Quercetinestablished pharmacology of each component

Quercetin inhibits CYP3A4 and several sulfotransferases in the gut wall, the same first-pass machinery that furanocoumarins act on. Pairing them raises the chance that a third co-formulated compound reaches the circulation less altered. Useful to know when building a multi-botanical, and it is mechanistic reasoning rather than a co-administration study.

Angelica Dahurica Root + Turmeric Curcuminestablished pharmacology of each component

Curcuminoids inhibit intestinal CYP and UGT enzymes, overlapping with the furanocoumarin effect on the same barrier. In a shared capsule the two can each reduce first-pass loss of the other. Nobody has measured this specific pair, so the row is mechanism only.

Angelica Dahurica Root + Licorice Roottraditional formula practice

Licorice root appears as the harmonising component in a large share of the classical formulas that also carry Angelica dahurica root. The pairing is a formulation convention with a long record of use rather than a measured pharmacological interaction. Worth noting that glycyrrhizin has its own mineralocorticoid-like effect on sodium and potassium handling, which is unrelated to the Angelica side.

Angelica Dahurica Root + Gingertraditional formula practice

Ginger and Angelica dahurica root are both used in the warming, dispersing group of traditional preparations and are frequently decocted in the same pot. The basis here is documented co-use, not a shared molecular target. Gingerols and furanocoumarins are chemically unrelated fractions.

Angelica Dahurica Root + Magnolia Barktraditional formula practice

Magnolia-derived materials sit alongside Angelica dahurica root in traditional preparations aimed at comfortable nasal airflow. The pairing is a convention of formula design, and the two carry entirely different marker compounds. No combination measurement supports a pharmacological interaction.

Peppermint oil is a common co-formulant where a product is built around a sensation of clear nasal airflow, which is the traditional use context for Angelica dahurica root. Menthol acts on cold-sensitive TRPM8 receptors, a completely separate route from anything in the root. The pair is a formulation choice, described here so a brand knows the two claims are independent.

Angelica Dahurica Root + Ginseng Panaxtraditional formula practice

Panax ginseng and Angelica dahurica root co-occur in traditional multi-herb decoctions. The documented basis is that pattern of co-use. Ginsenosides and furanocoumarins have no shared target, so a brand should not read a mechanistic partnership into the pairing.

Who should be cautious

Nothing specific on file for Angelica Dahurica Root. Match the label to the daily amount above, and tell your doctor what you take.

Not medical advice. Show the label to your pharmacist.

What Angelica Dahurica Root actually does.

Established

Angelica dahurica root is characterised by its coumarin fraction, with imperatorin, isoimperatorin and byakangelicin among the marker furanocoumarins used to identify the material.

Established

Linear furanocoumarins absorb ultraviolet A light and can form covalent adducts with DNA in skin cells, which is the accepted chemical basis for the increased skin sensitivity to sunlight that follows exposure to furanocoumarin-rich plants.

Established

Furanocoumarins act as mechanism-based inhibitors of CYP3A4 in the intestinal wall, the same class of enzyme interaction described for grapefruit constituents, which means the effect outlasts the presence of the compound itself.

Established

The lipophilic coumarin fraction extracts far more completely into ethanol or supercritical carbon dioxide than into a water decoction, so a hot-water preparation and an alcohol extract of the same root are chemically different materials.

Grown, 6 steps on record

Where Angelica Dahurica Root comes from.

Roots are dug up, cleaned and dried, then either simmered into a tea or soaked in alcohol to pull out the active compounds. Alcohol pulls out far more of the light-sensitising compounds than water does, so two products from the same root can behave differently.

Made from a plant. What ends up in the capsule tracks the harvest, so batch testing and a stated marker matter more here than with a made molecule.

Starts as
Cultivated Angelica dahurica roots

Roots of cultivated Angelica dahurica, grown mainly in northeastern China, Korea and Japan and lifted at the end of the growing season when the root has bulked.

Converted by
Washing and drying

Roots are washed, topped and dried whole or in slices. Two drying practices exist in the trade: hot-air or sun drying, and sulfur fumigation, which bleaches the slice and discourages mould during storage. Sulfured material carries sulfite residue and a different surface colour; unsulfured material browns more and depends on faster drying. Neither is presented here as the one to buy.

Extracted by
Decoction or alcohol percolation

Water decoction pulls the polar fraction; ethanol percolation or supercritical carbon dioxide pulls the coumarins and volatiles. The choice sets what the finished extract actually contains.

Purified by
Filtration and concentration

The liquor is filtered to remove root solids, then concentrated under reduced pressure to protect the volatile fraction.

Standardised to
Marker assay

Where the material is sold as standardised, imperatorin or total coumarins are quantified by HPLC against a reference standard and the extract is adjusted with a carrier to the declared figure.

Ends up as
Powder, granule or slice

Spray drying or vacuum drying onto maltodextrin or a similar carrier gives the powder that goes into capsules; the traditional trade sells the dried slice itself.

Labels almost never state whether a lot was sulfur-fumigated during drying, and they rarely state which solvent produced the extract, which is the detail that determines the furanocoumarin content.

Getting Angelica Dahurica Root from food.

The whole-food sources on file. A supplement closes the gap, it does not replace dinner.

None

A gram-for-gram figure (how much of each you would eat to match a dose) will appear here once it is sourced and reviewed. This page will not print a number it cannot cite.

The forms it comes in.

Bai zhi, dried root slicesWhole root tissue carrying the intact coumarin, polysaccharide and volatile fractionsFits Traditional decoction, where the material is simmered and the water phase consumedTrade-off The lipophilic furanocoumarins transfer only partly into water, and slice quality and drying method vary between lots
Hot-water extract, spray driedConcentrated aqueous phase, richer in polysaccharide and polar coumarin glycosides than in free furanocoumarinsFits Capsules and sachets that aim to reproduce the traditional decoction in a dry formatTrade-off Marker furanocoumarin content is usually low, so a coumarin specification may not be meaningful on this form
Standardised coumarin extractAlcohol percolate concentrated and assayed for imperatorin by HPLCFits Products that want a declared marker compound and lot-to-lot consistency in the coumarin fractionTrade-off Concentrating the coumarins concentrates the furanocoumarins that carry the ultraviolet sensitivity and the CYP3A4 inhibition
Root essential oilTerpene and phenylpropanoid volatiles plus carried-over lipophilic coumarinsFits Topical and aromatic uses where the volatile fraction is the pointTrade-off Dosing is by drops of a highly concentrated oil, and the composition shifts with harvest and distillation conditions
What the strongest studies found

The essence, in one line each.

  1. A multi-ingredient formula containing Angelica dahurica root lowered self-reported everyday aches and discomfort in healthy adults compared with placebo, so the result belongs to the blend and not to the root on its own.Randomised trial. Evans et al., 2020 (Nutrients). PMID 32575480
  2. A review of traditional Chinese medicine materials used topically on burn wounds names Angelica dahurica among the constituents discussed, describing proposed mechanisms rather than reporting an outcome for the root on its own.Narrative review. Liu et al., 2025 (Frontiers in Pharmacology). PMID 41333017
  3. A review of Kampo herbal ointments used on skin lists Angelica dahurica root among the traditional constituents of those ointments and summarises the proposed skin-repair mechanisms attributed to the class.Narrative review. Paul-Traversaz et al., 2023 (Frontiers in Pharmacology). PMID 36860294

These are the studies our verdict leans on, chosen from the 55 we read for Angelica Dahurica Root. The full linked list is below.

Side effects reported to the FDA

Problems people have reported.

Read this carefully. These are 56 voluntary, unverified reactions reported to the FDA (openFDA). The number mostly reflects how popular Angelica Dahurica Root is, not how risky it is. A report is not proof Angelica Dahurica Root caused anything. It is a signal of what to watch for, nothing more.

Dry Skin
2
Abscess Limb
1
Anorectal Swelling
1
Application Site Burn
1
Application Site Haemorrhage
1
Application Site Pain
1

Source: openFDA adverse-event reports. Voluntary reporting, not an incidence rate.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.