Cross-referencing clinical data
A pairing appears on this page only when a trial gave both ingredients together and measured the result. Flavones (various) has none that clears that bar.
Stitching two separate single-ingredient studies into a pairing is the one thing this engine will not do. When a study of the combination itself holds up at source, it lands here with its citation.
No invented synergy. Where actives were studied on their own rather than together, the record shows each on its own evidence, never a combined effect no trial measured.
Research strength. Research strength says how much work stands behind the combination. It is never a product score.
Independent record. Every finding is cited to a named trial, dated, and never written by the brand.
20 pairings are live across the library today. Checked 20 July 2026.
No study gave these as a pair, so they are not in the card above. But the reason they belong together is settled biochemistry, not a guess, so it is worth knowing.
When a flavone donates a hydrogen atom to a radical it becomes a phenoxyl radical itself, and ascorbate can reduce that species back to the parent phenol. The chemistry is well described in solution and in model membranes. Whether the same recycling loop changes any measured outcome in a person is a separate question that this mechanism does not answer.
Both classes are handled by intestinal and hepatic UGT and SULT enzymes, which have finite capacity. Taken together at high intake they compete for the same conjugation route, which can raise circulating unconjugated levels of one or both. That is a pharmacokinetic point, not a claim of added benefit.
Phospholipid complexes and lecithin dispersions raise the fraction of a poorly soluble flavone that stays in solution through the small intestine. This is a formulation answer to a dissolution problem. It changes exposure, not the intrinsic activity of the molecule.
Poplar-type propolis carries chrysin and related flavones as part of its native profile, so combining the two raises total flavone intake from a source that already contains them. The pairing is compositional overlap. Propolis content varies sharply with the botanical origin of the resin.
Flavones form coordination complexes with iron and copper through the 4-keto and adjacent hydroxyl positions. In the gut lumen that lowers the fraction of a non-heme iron dose available for uptake. Spacing the two apart is the usual handling.
The same keto-hydroxyl chelation site that binds iron also binds zinc and copper, so a high polyphenol load in the same serving reduces free divalent mineral in the lumen. The size of the effect depends on the flavone concentration and on what else is in the meal.
A large share of ingested flavones reaches the colon unabsorbed, where bacterial enzymes cleave the C ring into phenylacetic and phenylpropionic acid fragments that are then absorbed. Which fragments appear depends on which organisms are present. This is why two people given the same dose show different metabolite profiles.
Nothing specific on file for Flavones (various). Match the label to the daily amount above, and tell your doctor what you take.
Not medical advice. Show the label to your pharmacist.These are the studies our verdict leans on, chosen from the 2 we read for Flavones (various). The full linked list is below.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.