HICA Alpha-Hydroxyisocaproic supplementation for targeted health support.
No. Both are leucine metabolites but different compounds. HMB (beta-hydroxy beta-methylbutyrate) has more research. HICA (alpha-hydroxyisocaproic acid) is newer to supplements.
Not directly. It may support recovery and reduce muscle breakdown. Muscle building still requires training, protein, and calories. HICA is supportive, not primary.
It appears to inhibit certain enzymes involved in muscle protein breakdown. The exact mechanisms aren't fully characterized.
Click through to the studies bar for the evidence base.
See the dosing guide below.
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Some ingredients build up over weeks. Others act fast.
The compound effect of consistent dosing.
Check the cautions section if you have a pre-existing condition.
Some ingredients you feel. Others just work in the background.
Limited. A few studies show promise for reducing DOMS and supporting lean mass. More research needed. Not as well-studied as creatine or HMB.
HMB has more research backing it. HICA is less studied. If you've tried HMB, HICA might offer something different. They can theoretically be combined.
Studies used divided doses (500mg three times daily). Timing relative to training doesn't seem critical.
Most research uses 1.5g daily. Below 1.0g, you're probably wasting money. Above 2.0g, no extra benefit. The curve plateaus. Safe upper limit ~ 3.0g.
HICA Alpha-Hydroxyisocaproic has emerging evidence.
Produced naturally in the body from leucine metabolism · Found in trace amounts in fermented foods like cheese
HICA Alpha-Hydroxyisocaproic interacts with other supplements and meds. The analyzer flags interactions, dose mismatches, and timing collisions across your whole list.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.