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Verified by IngredientMD/Equate/Prenatal Multivitamin + DHA
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Prenatal Multivitamin + DHA.

Stronger in a pairEquate, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Equate.

Iodine is the lead active here, studied most for iodine status. 13 human studies on Iodine back this formula, each one cited. Each serving carries 200 mg of DHA, inside the range the published research used. Who it fits: made for women, adults.

Clinically dosedFull label disclosure
6Active ingredientsWell studiedResearch base76Human studies
Prenatal Multivitamin + DHAVerified by IngredientMD
EquateIngredientMD
The verdict
Stronger in a pair
For Made for women, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Folic Acid: MethylationExtensively studied
Iron: Iron statusWell studied
DHA: Omega 3 indexExtensively studied
Vitamin D3: Filling everyday nutrient gapsExtensively studied
Calcium: Filling everyday nutrient gapsExtensively studied
Iodine: Iodine statusKey driver

How we read this product

Source: Supplement facts
Supplement Facts panel for Prenatal Multivitamin + DHA
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 6 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Stronger in a pair".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
76
Human studies
150 mcg
Iodine
800 mcg
Folic Acid
800 mcg per serving sits inside the studied 400 mcg-800 mcg range
Folic Acid, NIH ODS + Bailey 2015 review
27 mg per serving sits inside the studied 18 mg-27 mg range
Iron, NIH ODS + WHO guidelines
200 mg per serving sits inside the studied 200 mg-500 mg range
DHA, Mozaffarian & Rimm 2006 JAMA systematic review; ISSFAL 2004 recommendations
150 mcg per serving sits inside the studied 150 mcg-200 mcg range
Iodine, NIH ODS + Zimmermann 2009 review

Cross-checked against 1,784 documented interactions for these actives.

Read the evidenceFolic Acid, the evidence →Iron, the evidence →DHA, the evidence →Vitamin D3, the evidence →Calcium, the evidence →Iodine, the evidence →

Inside the formula

Folic Acid
14 studies
Methylation
Extensively studied
Iron
Iron status
Well studied
DHA
Omega 3 index
Studied 200 mg to 1.5 g a day
Extensively studied
Vitamin D3
20 studies
Filling everyday nutrient gaps
Extensively studied
Calcium
13 studies
Filling everyday nutrient gaps
Extensively studied
Iodine
13 studies
Iodine status
Studied 150 mcg to 500 mcg a day
Key driver
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

43 more
The people it speaks to

60.2% of US adults aged 20 and over

took a dietary supplement in the past 30 days, and 38.7% took two or more, in the 2021 to 2023 National Health and Nutrition Examination Survey.

CDC National Center for Health Statistics, 2026
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
DHA

Meta-analysis, 2011

In trials giving DHA by itself, DHA lowered triglycerides and raised HDL cholesterol by about 4.5 mg/dL compared with placebo.

The paper
Iron

Meta-analysis, 2025

Across 20 trials in pregnant women, iron-folic acid formulations varied in hemoglobin response and reported tolerance, with dose and frequency mattering more than the specific iron salt.

BMC pregnancy and childbirth
Vitamin D3

Meta-analysis, 2024

Across 10 trials in 318 athletes, vitamin D3 raised blood vitamin D by about 14.8 nmol/L and hinted at better muscle strength, though few trials leave that uncertain.

Frontiers in Nutrition
Vitamin D3

Randomised trial, 2025

Vitamin D3 supplementation changed the inflammatory protein CHI3L1 and oxidative stress markers in adults with a chronic demyelinating condition. These are markers, not clinical outcomes.

Neuropsychopharmacology Reports
Iodine

Systematic review and meta-analysis, 2020

In pregnant women with mild to moderate iodine deficiency, iodine lowered a thyroid marker and curbed the usual pregnancy rise in thyroid size. Infant cognitive, language and motor scores showed no change across trials.

American Journal of Clinical Nutrition
Folic Acid

Meta-analysis, 2026

Pooled data found that women who had been pregnant before were more likely to take folic acid, an association about behavior, not an effect of the vitamin itself.

BMJ open
Iodine

Meta-analysis, 2026

In pregnant women with low iodine status, iodine was linked to lower TSH and thyroglobulin in the blood, both markers rather than health outcomes.

Frontiers in Public Health
Iron

Randomised trial, 2022

In 120 pregnant women, 24 mg iron as ferrous bisglycinate absorbed better within two hours than 66 mg ferrous fumarate, both raising iron levels over six months, with fewer gut side effects for bisglycinate.

Nutrients
Iodine

Systematic review, 2021

Across pooled studies, iodine supplementation in pregnancy shifted maternal iodine status and thyroid function measures, while effects on offspring endpoints were inconsistent between studies.

European Journal of Endocrinology
Vitamin D3

Meta-analysis, 2024

Across 20 studies, daily vitamin D3 raised blood vitamin D levels by about 10.4 nmol/L more than the same dose of vitamin D2, roughly 40 percent more.

Advances in Nutrition
Folic Acid

Meta-analysis, 2025

Across pooled trials, folic acid consistently lowered a blood marker called homocysteine, with less consistent change in more meaningful health outcomes.

BMC nutrition
Iron

Meta-analysis, 2024

Pooling randomised comparisons, no clear difference was detected between heme and non-heme iron preparations in haemoglobin and ferritin response, with tolerance differing between forms.

European journal of nutrition
Iron

Meta-analysis, 2025

In children and adolescents with low iron stores, longer supplementation courses raised haemoglobin more than short courses, while higher doses added little beyond moderate doses.

PloS one
DHA

Meta-analysis, 2026

Across 9 placebo-controlled eccentric exercise trials in healthy adults, supplements combining DHA with EPA reduced delayed onset muscle soreness (Hedges g -0.75, 95% CI -1.14 to -0.36). The wider body of 43 studies was mixed, and the trials tested the two fats together rather than DHA alone.

Nutrients
Iron

Meta-analysis, 2025

Comparing dosing schedules, alternate-day oral iron produced haemoglobin gains that were not clearly different from daily dosing, while fewer gastrointestinal complaints were reported.

BMC pharmacology & toxicology
Iodine

Systematic review, 2021

In areas with low population iodine intake, supplementation during pregnancy was associated with better neurocognitive development scores in offspring in some but not all included studies.

Archives of Endocrinology and Metabolism
Folic Acid

Randomised trial, 2025

In a double-blind noninferiority crossover, the authors did not detect a difference in the primary blood marker between folic acid and placebo. A failure to detect a difference is not evidence that none exists.

The American journal of clinical nutrition
Vitamin D3

Meta-analysis, 2014

Across 23 trials of 4,082 adults, vitamin D raised bone mineral density at the femoral neck by about 0.8%, with no measurable change at the spine, hip, or other sites.

Lancet
Iron

Systematic review, 2013

Across 111 studies covering 10,695 people, ferrous fumarate carried the highest reported side-effect rate among the oral iron supplements compared, at 47.0 percent overall and 43.4 percent gut-related.

Current Medical Research and Opinion
DHA

Meta-analysis, 2024

Pooling 9 randomised trials of DHA given before or after birth, infants in the DHA groups scored 1.47 points higher on the Psychomotor Development Index (95% CI 0.23 to 2.72), with no difference detected on the Mental Development Index.

Frontiers in Neurology

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people20 human studies on Vitamin D3 back this formula, each one cited.
  • A mechanism that is settledHow Folic Acid and Iron work is settled pharmacology.
  • Studied together, not just separatelyIron and Calcium have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Serving amount inside the studied rangeEach serving carries 200 mg of DHA, inside the range the published research used.
  • A stated daily maintenance amountDHA is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a softgel, so the active is already dissolved in oil and the shell keeps it away from air and light.
  • The exact form, describedThe label names its forms exactly: Folic acid (pteroylmonoglutamic acid), Ferrous fumarate, Algal oil, triglyceride form. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeFolic Acid is made by synthetic.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Folic Acida median of about 36 weeks of daily intakeBuilds with daily use

    A systematic review and Bayesian meta-analysis drew on 108 articles from 14,002 screened records and modelled blood folate against folic acid intake using one-compartment pharmacokinetic models. Red blood cell folate rose 1.78 fold from baseline to steady state at 375 to 570 ug folic acid per day, and reaching that steady state took a median of 36 weeks, 95% credible interval 27 to 52 weeks. Serum or plasma folate rose 11.6% for every 100 ug per day of folic acid intake, 95% credible interval 8.4 to 14.9.

    Strong
  • Folic Acidabout 18 days for serum folate to reach its maximumBuilds with daily use

    A kinetic study in six healthy men aged 22 to 31 gave 3.6 umol per day, 1.6 mg, of deuterium-labelled folic acid for four weeks, with folate tracked in serum, erythrocytes and urine by microbiological assay and gas chromatography mass spectrometry. Serum folate reached its maximum concentration in about 18 days, while isotopic labelling of erythrocyte folate kept rising across the whole four weeks. After supplementation stopped, red blood cell folate and urinary folate excretion declined linearly, and serum folate fell with a slow-phase half-life of 18.7 days. One study, six men, no control group.

    Early
  • Ironwithin 24 hours of a single doseMeasured within a day

    A randomised crossover study in 54 nonanemic young women with plasma ferritin at or below 20 ug/L gave labelled iron sulfate as single fasting morning doses of 40, 60, 80, 160 and 240 mg. Twenty four hours after doses of 60 mg or more, serum hepcidin was raised and fractional iron absorption from the following dose was 35% to 45% lower. Across the dose range a sixfold rise in dose, 40 to 240 mg, produced a threefold rise in iron absorbed, 6.7 to 18.1 mg. Total iron absorbed from three doses inside 24 hours was not significantly greater than from two morning doses. The measure was iron absorption and serum hepcidin, not a symptom.

    Promising
  • DHAabout eight weeks of daily useBuilds with daily use

    In a randomised single-blind trial, 20 participants took either fish oil supplying 1,296 mg EPA and 864 mg DHA daily or flaxseed oil for eight weeks, with erythrocyte membrane and plasma samples drawn at weeks 0, 4, 8, 10, 12, 14, 16 and 24. On fish oil, erythrocyte membrane EPA rose 300 percent and DHA rose 42 percent by week eight. Levels held until about week 12 and then declined across the post-supplementation sampling, faster in plasma phospholipids than in erythrocyte membranes. Membrane fatty acid content was measured, not a symptom, and this is one trial of 20 people.

    Cao et al., 2006PMID 17053155
    Promising
  • DHAabout five to seven days of daily useBuilds with daily use

    In a randomised double-blind crossover trial, healthy men and women aged 19 to 34 took capsules supplying about 4 g DHA per day, with plasma sampled at days 0, 1, 3, 7, 14 and 28. DHA concentrations tripled and so did DHA-derived oxylipins. Increases were detectable as early as day 1, and 11 of 12 individual DHA oxylipins plus total DHA oxylipins reached a plateau by days 5 to 7. The plateau came earlier and was reached by more oxylipins in females than in males. Plasma marker chemistry was measured, not a feeling.

    Gabbs et al., 2021PMID 33097936
    Promising
  • Vitamin D3about 3 months of daily useBuilds with daily use

    In the trial record, blood vitamin D rises for about 3 months of daily vitamin D3 and then holds at a plateau, near 69 nmol/L at 1,000 IU a day, from a starting level near 41 nmol/L.

    Early
2 more
  • Calciumwithin about one to six hours of a single doseMeasured within a day

    A randomised cross-over trial in ten women of mean age 69 gave a single 500 mg dose of calcium as citrate fasting, citrate with a meal, fortified juice or a dairy product meal, with blood drawn before and at 1, 2, 4 and 6 hours. Serum ionised and total calcium increased significantly from baseline over six hours, with the rise similar after fortified juice, delayed when citrate was taken with a meal and smaller after the dairy meal. A separate double-blind cross-over trial in 25 postmenopausal women measured parathyroid hormone and a bone resorption marker 12 hours after a single calcium dose. Ten participants is a small sample, and what moved was blood chemistry, not a sensation.

    Promising
  • Iodinefrom about eight weeks, deepening through twenty-four weeksBuilds with daily use

    In a 24 week randomised double-blind placebo-controlled trial in 112 mildly iodine-deficient New Zealand adults aged 18 to 40, 150 micrograms of iodine a day as potassium iodate lowered thyroglobulin, a blood marker of iodine status, by 12 percent at 8 weeks, 20 percent at 16 weeks and 27 percent at 24 weeks compared with placebo. Median urinary iodine reached 168 micrograms per litre against 79 on placebo. TSH and free T4 stayed within normal range and did not change significantly.

    Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

Six ingredients, from each one's own page.

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • Ferrous fumarate

    Ferrous salt of fumaric acid, about 33 percent elemental iron, moderately water-soluble

    Fits
    Products needing a high iron payload in a small tablet or capsule footprint
    Trade-off
    Delivers a high elemental dose per unit, and the unabsorbed remainder reaching the colon is what drives the digestive complaints reported with ferrous salts
  • Cholecalciferol (vitamin D3)

    The animal-sourced form of vitamin D, made in skin under UVB light and produced commercially from lanolin. Fat-soluble, so it travels with dietary fat and is stored in body fat.

    Fits
    Raising and holding vitamin D status, and the form most supplement trials use.
    Trade-off
    Being fat-soluble it accumulates with sustained high dosing, so intakes are set against the tolerable upper level rather than topped up freely.

    In a 12-week double-blind randomised controlled trial in 108 young women in urban Bangalore, most of whom began vitamin D-deficient, daily vitamin D3 at 400, 600 or 800 IU in a fortified wafer raised serum 25-hydroxyvitamin D, parathyroid hormone fell over time, and effects on bone-turnover markers were modest and not dose specific. The 800 IU dose brought 65 percent of participants to sufficiency.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Softgel

It is a softgel, so the active is already dissolved in oil and the shell keeps it away from air and light.

Best forFat-soluble actives and oils: vitamin D, vitamin E, omega-3, CoQ10.
Recurring supply suggested

Because the effect builds and holds only with continued daily use, a steady recurring supply is the practical way to keep it going.

Questions shoppers ask

Is Prenatal Multivitamin + DHA independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Prenatal Multivitamin + DHA?
Prenatal Multivitamin + DHA is built on Folic Acid, Iron, DHA, Vitamin D3, Calcium, Iodine. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 1,784 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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