57.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health StatisticsLifters who read the panel and want every active at a dose that does something. The pre-workout that shows its work. Every ingredient is on the label at an exact dose, no proprietary blends hiding a pixie-dust sprinkle. And the doses are real: 8 g citrulline malate, 4 g beta-alanine, 2.5 g betaine, all at or above what the studies use. Informed Choice certified and sweetened with stevia instead of the usual artificial load.
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Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
57.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Systematic review and meta-analysis, 2021
Across 8 studies, taking 6 to 8 grams of citrulline malate 40 to 60 minutes before strength training raised repetitions completed before muscular failure by about 6.4 percent.
International Journal of Sport Nutrition and Exercise MetabolismSystematic review and meta-analysis, 2020
Combining individual data across trials, about 99 percent of people taking beta-alanine raised their muscle carnosine, though modelling suggests typical doses don't fully saturate muscle stores.
Frontiers in PhysiologyRandomised trial, 2025
In 21 amateur cyclists, two weeks of 3 g of betaine a day made a 60 km time trial 1.41 minutes faster than placebo, a modest gain in endurance.
NutrientsRandomised trial, 2024
Over 28 days, 15 healthy adults with moderate stress taking a branded L-theanine ingredient had perceived-stress scores fall 17.98%, alongside routine safety monitoring.
Neurology and TherapyRandomised trial, 2025
Over five days, 15 young women with menstrual discomfort drinking a chamomile and theanine beverage had self-reported pain ratings fall 57.17%, with mood and sleep ratings also changing.
Journal of Food and Drug AnalysisMeta-analysis, 2025
Pooling 8 trials in 176 middle-aged and older adults, l-citrulline improved how well blood vessels widen by about 1.8 percentage points, with no clear change in artery stiffness.
Frontiers in NutritionRandomised trial, 2018
In untrained women resistance training for eight weeks, 2.5 g/day of betaine reduced body fat by about 3.3 percent versus 1.7 percent with placebo.
Journal of the International Society of Sports NutritionMeta-analysis, 2026
Across 11 trials in 312 women, beta-alanine improved time to exhaustion, though several other performance measures were too imprecise to call, with very low certainty.
Front NutrSystematic review, 2020
Across 9 trials, 200 to 400 mg a day of L-theanine may help lower stress and anxious feelings in people facing stressful situations.
Plant Foods for Human NutritionRandomised trial, 2019
In a 4-week trial in 30 healthy adults, 200 mg a day of L-theanine improved sleep quality scores, with faster sleep onset and less disturbance.
NutrientsRandomised trial, 2024
In 20 male volleyball players given 4.8 g of beta-alanine daily for 8 weeks of sprint training, vertical and horizontal jump gains were larger than with training alone.
Scientific ReportsRandomised trial, 2026
In 22 resistance-trained adults given 6.4 g of beta-alanine daily for 4 weeks, repetitions completed during drop-set and bi-set training increased, with no detected change in psychological responses.
Journal of Strength and Conditioning ResearchSystematic review and meta-analysis, 2019
Across 8 trials, L-citrulline lowered the top blood pressure number by about 4 points, with a drop in the bottom number only at doses of 6 grams a day or more.
Avicenna Journal of PhytomedicineA median improvement of about 2.85 percent in exercise measures
Improves the ability to keep going in efforts lasting one to four minutes. Measured in efforts lasting about one to four minutes (interquartile range -0.4 to 10.5 percent).
Meta-analysisMeta-analysis, 2025
Across 15 trials in middle-aged and older adults, l-citrulline or watermelon intake lowered blood pressure by about 4 points on the top number and about 2.5 points on the bottom number.
Clinical Nutrition ESPENSystematic review and meta-analysis, 2017
Across 40 placebo-controlled studies in 1,461 people, beta-alanine produced a small but significant overall gain in exercise outcomes (effect size 0.18), with the clearest benefit for high-intensity efforts lasting roughly 0.5 to 10 minutes.
British Journal of Sports MedicineA small to moderate gain in maximal strength (standardized effect 0.47), largest in the lower body
Builds maximal strength when taken consistently over time. Measured in healthy people aged 15 to 60, pooled across 17 trials (0.04 to 0.89).
Meta-analysisMeta-analysis, 2021
Across pooled human trials, betaine lowered blood homocysteine by about 1.3 micromol/L compared with control.
Critical Reviews in Food Science and NutritionMeta-analysis, 2025
Pooling the randomised trials, L-theanine was linked to small improvements in self-reported sleep quality, while objective sleep measures showed no detectable difference.
Meta-analysisMeta-analysis, 2025
In healthy adults, across trials, L-theanine with caffeine modestly improved accuracy on an attention-switching task, and L-theanine alone modestly sped up choice reaction time.
Nutrition ReviewsSystematic review, 2026
The review of citrulline supplementation in postmenopausal women reports vascular measures as the most consistently affected domain, with muscular and metabolic findings less consistent across the included studies.
BMC Women's HealthMeta-analysis, 2025
Across 21 randomised trials, l-citrulline showed no overall effect on body weight, fat mass or fat-free mass, with reductions in fat mass only in exploratory subgroups over age 40 or above 6 g a day.
NutrientsMeta-analysis, 2021
The same betaine dose that lowers homocysteine also raised total cholesterol by about 0.34 mmol/L across six trials, with no change detected in LDL, HDL or triglycerides.
Journal of Dietary SupplementsMeta-analysis, 2022
Pooling trials, betaine supplementation showed no detectable change in body fat or lean mass.
British Journal of NutritionPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
In a randomised double-blind crossover trial in 19 recreationally active women, a single 8 g dose of citrulline malate taken 60 minutes before testing raised total work in a 5-repetition isokinetic leg extension protocol compared with placebo, with no difference in peak torque and no difference in the 50-repetition protocol. A separate crossover trial in 10 well-trained men using 12 g 60 minutes before high-intensity cycling found no change in time to exhaustion or power.
In the trial record, muscle carnosine rises about 59% over 4 weeks of daily beta-alanine, with further gains, about 80%, by 10 weeks.
In a randomised double-blind crossover trial in 12 resistance-trained men, 14 days of betaine at 1.25 g twice daily raised bench throw power and isometric bench press force compared with placebo, with no change in jump squat power or repetitions completed. A meta-analysis of 17 trials in 317 participants reported a modest pooled effect on maximal strength of 0.47 standardised mean difference for regimens of at least 7 days.
Two double-blind placebo-controlled crossover trials measured attention at a fixed interval after one oral dose. In 24 overnight sleep-deprived adults aged 20 to 25, a 200 mg dose tested 45 minutes post-dose reduced false alarms on a traffic-scene recognition task and raised target-distractor discriminability. In 27 healthy young adults tested 50 minutes post-dose, 400 mg shortened the parietal P3b event-related potential latency against placebo, with no significant change at 100 or 200 mg. Both trials measured task and electrophysiological markers, not a subjective feeling.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
What each form is, and where it fits in a formula. Measured findings carry the study that reported them.
L-citrulline combined with malic acid, sold most often as a 2:1 or 1:1 blend by weight of citrulline to malate. The malate is the salt of the same acid found in tart fruit.
In a randomized double-blind placebo-controlled crossover trial, 41 men took a single 8 g dose of citrulline malate before resistance training. Bench-press repetitions to fatigue rose across the later sets and reported muscle soreness at 24 and 48 hours was lower than placebo.
The free beta amino acid, freely water soluble, supplied as a crystalline powder
The single L-enantiomer as a free amino acid, the form found in tea leaf and the form used in essentially all human trials.
Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.