Cross-checked against 59,000+ documented supplement and drug interactions.
The same mineral, carried differently.
What each form is, and where it fits in a formula. Measured findings carry the study that reported them.
- Magnesium bisglycinate
Magnesium chelated to two molecules of the amino acid glycine, rather than carried as a mineral salt.
- Fits
- evening and sleep-positioned formulas, and pregnancy formulas aimed at leg cramps, which is where its trials sit
- Trade-off
- the measured effects are small (Cohen d of 0.2 for insomnia severity at week 4), and the glycine share of the molecule leaves less elemental magnesium per capsule than a mineral salt
In a randomised double-blind placebo-controlled trial in 155 adults aged 18 to 65 reporting poor sleep quality, magnesium bisglycinate at 250 mg elemental magnesium daily reduced Insomnia Severity Index scores from baseline to week 4 by 3.9 points (95 per cent CI 5.8 to 2.0) against 2.3 points (95 per cent CI 4.1 to 0.4) on placebo (p = 0.049), an effect the authors describe as small (Cohen d 0.2), with no significant differences in other psychological outcomes. In a double-blind randomised placebo-controlled trial in 86 pregnant women at 14 to 34 weeks gestation with leg cramps at least twice weekly, magnesium bisglycinate chelate at 300 mg daily for four weeks achieved a 50 per cent reduction in cramp frequency in 86.0 per cent against 60.5 per cent on placebo (P = 0.007), with no significant between-group difference in nausea or diarrhoea.
Schuster et al., 2025 (Nature and Science of Sleep)PMID 40918053
Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.
- Is Magnesium Glycinate independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Jul 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in Magnesium Glycinate?
- Magnesium Glycinate is built on Magnesium Glycinate. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.