Magnesium GlycinateNHANES 2013 to 2016
About 48% of Americans
take in less magnesium than recommended from food and drink.
NIH Office of Dietary SupplementsMagnesium Glycinate
Magnesium Glycinate.
Verified by IngredientMD
People who titrate magnesium and want the gentlest, cleanest form. A clean, gentle magnesium done without the usual shortcuts. 120 mg of elemental magnesium as true bisglycinate, the chelated form that tends to sit easiest on the stomach, in a capsule that is basically just the mineral. No magnesium stearate, no fillers, hypoallergenic. The one thing to know: at 120 mg a capsule, you dose up to your target rather than getting it all in one.
Bisglycinate chelateNo magnesium stearateHypoallergenic
1Active ingredient120 mgElemental Mg per capsuleChelateBisglycinate form
Verified by IngredientMDThe receipts
120 mg
Elemental Mg per capsule
Chelate
Bisglycinate form
Chelated bisglycinate is chosen for absorption and GI tolerability
Magnesium bisglycinate, Pure Encapsulations label
Cross-checked against 59,000+ documented supplement and drug interactions.
Read the evidenceMagnesium glycinate, the evidence →
Inside the formula
In context
The gap this formula speaks to.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
Magnesium GlycinateBRFSS 2014
More than 1 in 3 US adults
regularly sleep less than the recommended seven hours a night.
Peer-reviewed analysisDaily usePublished 2024
59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 2024Daily usePublished 2015
61% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Magnesium Glycinate
Systematic review, 2019
Across 26 trials in 1,168 adults, magnesium supplementation lowered fasting blood sugar and fasting insulin, supporting normal blood sugar handling.
The paperZhao et al., 2019PMID 31758631
Magnesium Glycinate
Systematic review, 2021
Pooling three randomized trials in 151 older adults, magnesium shortened the time taken to fall asleep by about 17 minutes versus placebo, on low-quality evidence.
BMC Complementary Medicine and Therapies4 more
Meta-analysis, 2024
Trial evidence was too thin to judge magnesium for memory, but blood levels below 0.75 mmol/L tracked with a 43 percent higher decline risk than levels near 0.85, an association not a cause.
Advances in NutritionChen et al., 2024 (Advances in Nutrition)PMID 39009081
Meta-analysis, 2016
Across 34 double-blind trials in 2,028 adults, magnesium at a median 368 mg per day lowered systolic blood pressure by about 2.0 mmHg and diastolic by about 1.8 mmHg over a median three months.
The paperZhang et al., 2016PMID 27402922
Systematic review, 2024
Across the included trials, magnesium supplementation reduced muscle soreness and supported recovery from muscle damage after hard exercise, in physically active people.
Journal of Translational MedicineSystematic review, 2025
A pooled analysis of magnesium combined with vitamin D or E found changes in inflammation and blood fat markers in adults with excess weight, markers rather than health outcomes.
Frontiers in NutritionDeng et al., 2025 (Frontiers in Nutrition)PMID 40959697
Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Chemical form
The same ingredient, carried differently.
What each form is, and where it fits in a formula. Measured findings carry the study that reported them.
- Magnesium bisglycinate
Magnesium chelated to two molecules of the amino acid glycine, rather than carried as a mineral salt.
- Fits
- evening and sleep-positioned formulas, and pregnancy formulas aimed at leg cramps, which is where its trials sit
- Trade-off
- the measured effects are small (Cohen d of 0.2 for insomnia severity at week 4), and the glycine share of the molecule leaves less elemental magnesium per capsule than a mineral salt
In a randomised double-blind placebo-controlled trial in 155 adults aged 18 to 65 reporting poor sleep quality, magnesium bisglycinate at 250 mg elemental magnesium daily reduced Insomnia Severity Index scores from baseline to week 4 by 3.9 points (95 per cent CI 5.8 to 2.0) against 2.3 points (95 per cent CI 4.1 to 0.4) on placebo (p = 0.049), an effect the authors describe as small (Cohen d 0.2), with no significant differences in other psychological outcomes. In a double-blind randomised placebo-controlled trial in 86 pregnant women at 14 to 34 weeks gestation with leg cramps at least twice weekly, magnesium bisglycinate chelate at 300 mg daily for four weeks achieved a 50 per cent reduction in cramp frequency in 86.0 per cent against 60.5 per cent on placebo (P = 0.007), with no significant between-group difference in nausea or diarrhoea.
Schuster et al., 2025 (Nature and Science of Sleep)PMID 40918053
Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.
Available from Pure Encapsulations
Verified Jul 2026
Questions shoppers ask
- Is Magnesium Glycinate independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Jul 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in Magnesium Glycinate?
- Magnesium Glycinate is built on Magnesium Glycinate. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
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