Magnesium GlycinateNHANES 2013 to 2016
About 48% of Americans
take in less magnesium than recommended from food and drink.
NIH Office of Dietary SupplementsMagnesium Glycinate
Magnesium Glycinate.
Verified by IngredientMD
For people who titrate magnesium and want the gentlest, cleanest form. A clean, gentle magnesium done without the usual shortcuts. 120 mg of elemental magnesium as true bisglycinate, the chelated form that tends to sit easiest on the stomach, in a capsule that is basically just the mineral. No magnesium stearate, no fillers, hypoallergenic. The one thing to know: at 120 mg a capsule, you dose up to your target rather than getting it all in one.
Bisglycinate chelateNo magnesium stearateHypoallergenic
1Active ingredient120 mgElemental Mg per capsuleChelateBisglycinate form
Verified by IngredientMDThe receipts
120 mg
Elemental Mg per capsule
Chelate
Bisglycinate form
Chelated bisglycinate is chosen for absorption and GI tolerability
Magnesium bisglycinate, Pure Encapsulations label
Cross-checked against 59,000+ documented supplement and drug interactions.
Read the evidenceMagnesium glycinate, the evidence →
Inside the formula
In contextChecked 2026-09-10
The gap this formula speaks to.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
Daily usePublished 2024
59 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 2024Daily usePublished 2015
61% to 74%
of adults refilling a daily long-term medicine on their own had stopped within a year, against 33% to 44% of those whose refills were scheduled to one recurring pickup day, in a matched pharmacy cohort.
Cohort study, 2015Magnesium Glycinate2026-07-24
Meta-analysis, 2016
Across 34 trials in 2,028 adults, magnesium at about 368 mg daily for three months lowered systolic pressure by about 2.0 mmHg and diastolic by about 1.8 mmHg versus placebo.
The paperZhang et al., 2016PMID 27402922
Magnesium Glycinate2026-07-24
Systematic review, 2024
Across exercise studies, magnesium was linked to less muscle soreness and better recovery, with people training hard possibly needing 10 to 20 percent more than sedentary people.
Journal of Translational MedicineMagnesium Glycinate2026-07-24
Systematic review, 2021
Pooling three randomized trials in 151 older adults, magnesium shortened the time taken to fall asleep by about 17 minutes versus placebo, on low-quality evidence.
BMC Complementary Medicine and TherapiesMagnesium Glycinate2026-07-24
Systematic review, 2019
Across 26 randomized trials in 1,168 adults, magnesium supplementation lowered fasting blood glucose (standardized mean difference -0.32) and fasting insulin (-0.17), supporting normal glucose handling.
The paperZhao et al., 2019PMID 31758631
Magnesium Glycinate2026-07-24
Systematic review, 2025
A review gathered magnesium trials testing how often recurring headache attacks strike, and its own result and certainty rating are the figures to trust.
Cochrane Database of Systematic ReviewsMagnesium Glycinate2026-07-24
Meta-analysis, 2024
Across 5 trials and 12 cohorts, the trial evidence was too thin to judge magnesium supplements for thinking and memory, while blood magnesium near 0.85 mmol/L tracked with the lowest risk of later cognitive decline and levels below 0.75 mmol/L with a 43 percent higher risk, an association rather than a demonstrated cause.
Advances in NutritionChen et al., 2024 (Advances in Nutrition)PMID 39009081
Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Chemical formChecked 2026-09-10
The same mineral, carried differently.
What each form is, and where it fits in a formula. Measured findings carry the study that reported them.
- Magnesium bisglycinate
Magnesium chelated to two molecules of the amino acid glycine, rather than carried as a mineral salt.
- Fits
- evening and sleep-positioned formulas, and pregnancy formulas aimed at leg cramps, which is where its trials sit
- Trade-off
- the measured effects are small (Cohen d of 0.2 for insomnia severity at week 4), and the glycine share of the molecule leaves less elemental magnesium per capsule than a mineral salt
In a randomised double-blind placebo-controlled trial in 155 adults aged 18 to 65 reporting poor sleep quality, magnesium bisglycinate at 250 mg elemental magnesium daily reduced Insomnia Severity Index scores from baseline to week 4 by 3.9 points (95 per cent CI 5.8 to 2.0) against 2.3 points (95 per cent CI 4.1 to 0.4) on placebo (p = 0.049), an effect the authors describe as small (Cohen d 0.2), with no significant differences in other psychological outcomes. In a double-blind randomised placebo-controlled trial in 86 pregnant women at 14 to 34 weeks gestation with leg cramps at least twice weekly, magnesium bisglycinate chelate at 300 mg daily for four weeks achieved a 50 per cent reduction in cramp frequency in 86.0 per cent against 60.5 per cent on placebo (P = 0.007), with no significant between-group difference in nausea or diarrhoea.
Schuster et al., 2025 (Nature and Science of Sleep)PMID 40918053
Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.
Available from Pure Encapsulations
Verified Jul 2026
Questions shoppers ask
- Is Magnesium Glycinate independently verified?
- Yes. IngredientMD reviewed this formula independently and verified it in Jul 2026. The verdict is earned, not bought: brands can't edit or purchase it.
- What's in Magnesium Glycinate?
- Magnesium Glycinate is built on Magnesium Glycinate. Each ingredient links to its own evidence page on IngredientMD.
- Were ingredient interactions checked?
- Yes. The combination was screened against IngredientMD's interaction database.
- Who is IngredientMD?
- IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.
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