Alpha-Hydroxyisocaproic Acid supplementation for targeted health support.
HMB has more research. HICA is less studied. Both are leucine metabolites with anti-catabolic claims.
Leucine is better studied for muscle protein synthesis. HICA may have complementary anti-catabolic effects.
Some studies show slight lean mass increases. Effects are modest. Not a powerful muscle builder.
Click through to the studies bar for the evidence base.
See the dosing guide below.
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Some ingredients build up over weeks. Others act fast.
The compound effect of consistent dosing.
Check the cautions section if you have a pre-existing condition.
Some ingredients you feel. Others just work in the background.
Yes, your body makes HICA from leucine metabolism. Also found in some fermented foods.
Limited research, modest effects, and competition from better-studied supplements like leucine and HMB.
Athletes in caloric deficit or doing very high volume training where anti-catabolic support matters most.
Most research uses 1.5g daily. Below 0.5g, you're probably wasting money. Above 2.5g, no extra benefit. The curve plateaus. Safe upper limit ~ 3.0g.
Alpha-Hydroxyisocaproic Acid has emerging evidence.
Produced in the body from leucine metabolism. Found in small amounts in fermented foods where bacteria metabolize amino acids.
Alpha-Hydroxyisocaproic Acid interacts with other supplements and meds. The analyzer flags interactions, dose mismatches, and timing collisions across your whole list.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.