PaleoMeal DF.

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

• Studied in people22 human studies on Zinc back this formula, each one cited.
• A mechanism that is settledHow Protein and Vitamin A work is settled pharmacology.
• Studied together, not just separatelyProtein and Magnesium have been studied together, not only separately.
• Recent work on the recordThe most recent study on this record was published in 2026.
• Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
• The exact form, describedThe label names its forms exactly: Bone broth protein powder, Beta-carotene, Ascorbic acid. The record says what each one is and what it suits.
• Full label disclosureEvery ingredient on this label carries its own declared amount.
• Where it comes from and how it is madeProtein is made by animal.
• Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
• A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
• Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.

The combinations the trials actually measured.

One pairing in this formula has been studied as a combination in human trials. Each finding below is what a named study measured, cited and dated, never written by the brand.

• Iron + Vitamin CAbsorption

  In a controlled radioiron study in 63 men, adding ascorbic acid to a non-heme iron meal increased iron absorption in proportion to the dose, from about 1.6 times the meal alone at 25 mg to about 9 times at 1000 mg.

  Cook & Monsen, 1977 (Am J Clin Nutr)PMID 835510

  Promising

Findings from trials that studied these actives as a combination. Context for how the actives were tested together, not a statement about any individual and not a claim about this product.

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

• Vitamin D3about 3 months of daily useBuilds with daily use

  In the trial record, blood vitamin D rises for about 3 months of daily vitamin D3 and then holds at a plateau, near 69 nmol/L at 1,000 IU a day, from a starting level near 41 nmol/L.

  Vieth et al., 2001 (Am J Clin Nutr)PMID 11157326

  Early
• Ironwithin 24 hours of a single doseMeasured within a day

  A randomised crossover study in 54 nonanemic young women with plasma ferritin at or below 20 ug/L gave labelled iron sulfate as single fasting morning doses of 40, 60, 80, 160 and 240 mg. Twenty four hours after doses of 60 mg or more, serum hepcidin was raised and fractional iron absorption from the following dose was 35% to 45% lower. Across the dose range a sixfold rise in dose, 40 to 240 mg, produced a threefold rise in iron absorbed, 6.7 to 18.1 mg. Total iron absorbed from three doses inside 24 hours was not significantly greater than from two morning doses. The measure was iron absorption and serum hepcidin, not a symptom.

  Moretti et al., 2015 (Blood)PMID 26289639

  Promising
• Zincover about five days of lozenges started within 24 hours of symptom onsetBuilds with daily use

  Across three randomised placebo-controlled trials pooled as individual patient data (199 adults with naturally acquired colds, 80 to 92 mg of elemental zinc a day as acetate lozenges), 70 percent of the zinc group had recovered by day 5 against 27 percent on placebo, and colds ran 2.73 days shorter against a 7 day average duration. A separate meta-analysis of seven lozenge trials (575 participants, doses above 75 mg a day, zinc acetate or zinc gluconate) measured cold duration 33 percent shorter, with no significant difference between the two salts.

  Hemilä et al., 2017 (Open Forum Infect Dis)PMID 28480298

  Hemilä et al., 2016 (Br J Clin Pharmacol)PMID 27378206

  Hemilä, 2017 (JRSM Open)PMID 28515951

  Strong
• Zincabout two to four weeks of daily intakeBuilds with daily use

  In a controlled feeding study in nine healthy men, six weeks of restricted zinc intake raised DNA strand breaks in peripheral blood cells, and four weeks of repletion at 11 mg a day, with 20 mg of supplemental zinc for the first seven days, reversed the rise. In a separate randomised placebo-controlled trial in 40 Ethiopian women eating a high-phytate diet, 20 mg a day of zinc sulfate for 17 days lowered mean comet tail moment from 39.7 to 30.0 while plasma zinc did not change significantly. Both windows were measured on a DNA damage marker in blood cells, not on a symptom.

  Song and colleagues 2009, American Journal of Clinical NutritionPMID 19515738

  Joray and colleagues 2015, Nutrition ResearchPMID 25491347

  Early
• MCT Oil Powderblood ketones rise within about 4 hoursMeasured within a day

  In a 6-arm crossover, 15 healthy volunteers aged 65 to 73 took test fats after a 12-hour fast with ketones measured over the following 4 hours. A 20 g dose of caprylic acid (C8), the medium-chain fatty acid the ketogenic effect is mainly demonstrated for, raised blood beta-hydroxybutyrate relative to a sunflower-oil control, and coconut oil, which is about two thirds medium-chain triglycerides, raised it less per gram.

  Norgren et al., 2020 (Frontiers in Nutrition)PMID 32351966

  Promising

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

How each ingredient usually behaves over time.

8 ingredients, from each one's own page.

• ProteinThe same day

  Same day for the protein it adds to a meal. Joint and skin readouts in collagen peptide trials are measured after eight to twelve weeks of daily use.

  Its own page, the plain answer on timing ↗

• Vitamin AWeeks, not days

  Weeks to months. It is a status ingredient, so the change turns up in plasma carotenoid and retinol readings rather than in anything day to day.

  Its own page, the plain answer on timing ↗

• Vitamin CWithin hours

  Plasma levels climb within hours and plateau near the top of the band. Collagen-linked changes in gums and skin show up across weeks, on examination rather than by sensation.

  Its own page, the plain answer on timing ↗

• Vitamin D3About six to twelve weeks

  Blood 25-hydroxyvitamin D climbs over six to twelve weeks on a steady daily dose. It is a panel change first, and anything subjective trails behind it.

  Its own page, the plain answer on timing ↗

• IronTwo to four weeks

  Before everyday stamina shifts. Ferritin, the storage marker, climbs over months of steady daily intake rather than days.

  Its own page, the plain answer on timing ↗

• Magnesium

  A looser stool can turn up the same day at the higher end. Sleep and cramp changes usually settle in across two to four weeks, because it is refilling a body-wide store.

  Its own page, the plain answer on timing ↗

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

• Beta-carotene

  Chemically synthesised crystalline carotene, essentially a single all-trans isomer of high purity.

  Fits

  Standardised supplement and fortification use where a consistent, defined isomer content is wanted.

  Trade-off

  It supplies one isomer rather than the mixture found in a plant source, and the crystal needs a delivery system to be dispersible at all.

• Ascorbic acid

  The unbuffered acid, pKa around 4.2, fully water soluble and the reference form for most assays and trials.

  Fits

  Anyone matching a research dose or wanting no added mineral load.

  Trade-off

  The acidity can be noticeable in the stomach for some people at larger single doses, and it is hard on tooth enamel in chewable or powder-in-water use.

• Ferrous bisglycinate

  Iron chelated to two molecules of the amino acid glycine, rather than carried as a simple salt.

  Fits

  Trade-off

  at 18 mg it did not match 60 mg of ferrous sulfate for ferritin in a non-inferiority trial, and the meta-analysis found no significant difference in haemoglobin or ferritin among children

• Magnesium malate

  Magnesium held as a salt of malic acid, the four-carbon fruit acid that also sits in the citric acid cycle. The common di-magnesium form is roughly 15 percent magnesium by weight, dissolves in water and carries a mild tart note.

  Fits

  Powder and stick-pack formats where a tart fruit acid works with the flavour system rather than against it. Formulators also reach for it when a formula is themed around Krebs-cycle intermediates, and it works in capsules where a soluble organic salt is wanted at a moderate elemental load.

  Trade-off

  About a quarter of the elemental magnesium per gram of the oxide form, so a full daily amount means a bigger capsule or more than one per serving. No human outcome trial has tested the malate form on its own, so this row is chemistry and formulation logic, not a measured result.

• Zinc bisglycinate

  Zinc chelated to two glycine molecules through a nitrogen and an oxygen bond, the smallest amino acid available for chelation, giving a low molecular weight chelate of about 26 percent zinc by weight. It is a neutral-tasting dry powder with mild solubility and is stable across the pH range a capsule or tablet passes through.

  Fits

  Daily capsules, tablets and blends where a chelated organic form and a neutral taste are wanted, including formulas that pair zinc with other minerals in the same dose form. The small chelate size keeps the raw weight manageable at everyday zinc targets.

  Trade-off

  The supporting human study is a pilot intervention with ten young women per arm at 60 mg zinc daily, above the 40 mg tolerable upper intake level for adults, so the reassuring copper-status reading was taken at a dose most consumer formulas do not use, over only six weeks. No stable-isotope absorption study in humans has measured this form.

  In a six-week placebo-controlled pilot intervention in young adult women (10 per arm, 30 in total) at 60 mg zinc daily, a dose above the 40 mg tolerable upper intake level for adults, plasma zinc, described by the authors as the traditional assessment of zinc status, increased in all subjects given zinc glycinate, while no significant change was seen overall for zinc gluconate or placebo. Erythrocyte superoxide dismutase activity, used in that study as a marker of zinc-induced copper deficiency, was unchanged in all three groups over the six weeks. A 2024 narrative review of the chemical forms of zinc, written by authors employed by a supplement manufacturer, states that little information is available comparing the absorption and bioavailability of the different chemical forms. No stable-isotope absorption study in humans has measured this form.

  DiSilvestro 2015, Biol Trace Elem Res (pilot intervention, placebo-controlled)PMID 25877802

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.