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Verified by IngredientMD/Host Defense/Stamets 7 Capsules
VERIFIED BYingredientMD

Stamets 7 Capsules.

Stronger in a pairHost Defense, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Host Defense.

Maitake mycelium is the lead active here, studied most for a balanced gut microbiome. Cordyceps mycelium is the most studied active here, with 9 human studies behind it, each one cited. Who it fits: for everyone, adults.

Full label disclosure
7Active ingredientsWell studiedResearch base21Human studies
Stamets 7 CapsulesVerified by IngredientMD
Host DefenseIngredientMD
The verdict
Stronger in a pair
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Royal Sun Blazei mycelium: A balanced gut microbiomeWell studied
Cordyceps mycelium: A balanced gut microbiomeWell studied
Reishi mycelium: A balanced gut microbiomeWell studied
Maitake mycelium: A balanced gut microbiomeKey driver
Lion's Mane mycelium: Feeding the bacteria that make butyrateWell studied
Chaga mycelium: Immune resilienceWell studied
Mesima mycelium: A balanced gut microbiomeWell studied

How we read this product

Source: Supplement facts
Supplement Facts panel for Stamets 7 Capsules
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 7 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Stronger in a pair".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
21
Human studies
143 mg
Maitake mycelium
143 mg
Royal Sun Blazei mycelium

Inside the formula

Royal Sun Blazei mycelium
A balanced gut microbiome
Well studied
Cordyceps mycelium
A balanced gut microbiome
Well studied
Reishi mycelium
A balanced gut microbiome
Well studied
Maitake mycelium
A balanced gut microbiome
Key driver
Lion's Mane mycelium
Feeding the bacteria that make butyrate
Well studied
Chaga mycelium
Immune resilience
Well studied
Mesima mycelium
A balanced gut microbiome
Well studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

This formulaNHANES 2017-2018, published 2021

57.6%

During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.

CDC National Center for Health Statistics
The people it speaks toFieldwork 2017 to 2018

58% of the recommended fiber intake

was reached on average by US consumers, who ate 8.1 grams of fiber per 1,000 calories in 2017 to 2018 versus the 14 grams recommended, per USDA Economic Research Service analysis of federal food consumption survey data.

USDA Economic Research Service, 2023
The people it speaks toFieldwork March 28 to 29, 2023

34% of US adults

aged 18 and over report they experience abdominal discomfort or pain at least a few times per month, with women about twice as likely as men to report it several times weekly, per a 2023 Ipsos poll conducted for MDVIP.

Ipsos, 2023
11 more
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Reishi mycelium

Meta-analysis, 2016

Across five combined trials, reishi mushroom taken alongside standard care raised the measured share of three types of immune cells by about 3.9, 3.1 and 2.0 percentage points.

Cochrane Database of Systematic Reviews
Reishi mycelium

Randomised trial, 2005

Over eight weeks, a reishi polysaccharide extract lowered self-rated fatigue by about 28 percent from baseline versus 20 percent on placebo and raised the sense of well-being.

Journal of Medicinal Food
Maitake mycelium

Systematic review, 2009

A systematic search of ten databases found the human research on maitake to be limited and clustered around glucose handling and immune stimulation, with the authors calling for randomised trials.

Journal of the Society for Integrative Oncology
Reishi mycelium

Randomised trial, 2024

In older women, 2,000 mg of reishi mushroom extract daily for eight weeks increased immune response to a lab stimulus and shifted immune markers toward an anti-inflammatory pattern versus placebo.

British Journal of Nutrition
Reishi mycelium

Randomised trial, 2026

A randomised, double-blind trial of a multi-mushroom blend reported changes in self-rated stress, fatigue and sleep measures. Because the product was a blend, no result can be assigned to reishi alone.

Brain and Behavior
Maitake mycelium

Narrative review, 2026

A review links mushroom intake, mainly as a source of vitamin D2 from UV light and trace minerals, to bone-related blood markers, but it's a summary, not a controlled trial.

Pharmaceuticals

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people9 human studies on Cordyceps mycelium back this formula, each one cited.
  • A mechanism that is settledHow Royal Sun Blazei mycelium and Cordyceps mycelium work is settled pharmacology.
  • Studied together, not just separatelyRoyal Sun Blazei mycelium and Cordyceps mycelium have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
  • The exact form, describedThe label names its forms exactly: Agaricus fruiting body extract, standardised to beta-glucan, Fruiting body powder or extract, Water-extracted polysaccharide fraction. The record says what each one is and what it suits.
  • Full label disclosureEvery ingredient on this label carries its own declared amount.
  • Where it comes from and how it is madeRoyal Sun Blazei mycelium is made by more than one route.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Cordyceps myceliumwithin the hour of a single doseMeasured within a day

    In a randomised, double-blind, placebo-controlled crossover in 12 recreationally active young men, a single 1 g dose of standardised Cordyceps militaris extract taken 30 minutes before a maximal cycling test was followed by faster Stroop reaction times across the session compared with placebo.

    Early
  • Lion's Mane myceliumwithin about one to two hours of a single doseMeasured within a day

    Two small studies measured a same-day effect. In a randomised, double-blind, placebo-controlled parallel-groups pilot in 41 healthy adults aged 18 to 45, a single 1.8 g dose of lion's mane was followed by quicker Stroop task performance at 60 minutes after dosing (p = 0.005). In a separate randomised, double-blind, placebo-controlled crossover study, a single 1 g dose of Nordic-grown lion's mane was followed by changes in working memory, complex attention and reaction time measures two hours after ingestion. Both samples are small. A third acute crossover in 18 adults using a 3 g dose of a 10:1 fruiting body extract found no effect on composite cognition or mood at 90 minutes, with a change only on an individual pegboard test.

    Early

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

7 ingredients, from each one's own page.

1 more

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Format

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Best forMost standard doses, and anywhere a short, clean label is the point.
Recurring supply suggested

Because the effect builds and holds only with continued daily use, a steady recurring supply is the practical way to keep it going.

Questions shoppers ask

Is Stamets 7 Capsules independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Stamets 7 Capsules?
Stamets 7 Capsules is built on Royal Sun Blazei mycelium, Cordyceps mycelium, Reishi mycelium, Maitake mycelium, Lion's Mane mycelium, Chaga mycelium, and more. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 162 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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