24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 2022Maitake mycelium is the lead active here, studied most for a balanced gut microbiome. Cordyceps mycelium is the most studied active here, with 9 human studies behind it, each one cited. Who it fits: for everyone, adults.
Verified by IngredientMDThe panel on the left is the one we evaluated, line by line.
All 7 actives checked against the clinical evidence: dose, form, and what the research actually shows.
Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Stronger in a pair".
The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.
Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.
Cross-checked against 162 documented interactions for these actives.
Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.
24% of US adults
say digestive health is the most important aspect of their overall health, per a 2022 IFIC survey on gut health and probiotics.
International Food Information Council, 202252% of US adults
believe common digestive symptoms such as bloating and abdominal pain are just a normal part of life, per a 2026 Harris Poll conducted for Oshi Health.
The Harris Poll for Oshi Health, 202657.6%
During 2017 to 2018, 57.6% of US adults aged 20 and over reported using a dietary supplement in the past 30 days.
CDC National Center for Health Statistics58% of the recommended fiber intake
was reached on average by US consumers, who ate 8.1 grams of fiber per 1,000 calories in 2017 to 2018 versus the 14 grams recommended, per USDA Economic Research Service analysis of federal food consumption survey data.
USDA Economic Research Service, 202340% of US adults
aged 18 and over report they experience bloating at least a few times a month, with 5% saying they experience it daily, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202334% of US adults
aged 18 and over report they experience abdominal discomfort or pain at least a few times per month, with women about twice as likely as men to report it several times weekly, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202328% of US adults
aged 18 and over say that digestive issues impact the quality of their life, a share that rises to about a third among those aged 18 to 44, per a 2023 Ipsos poll conducted for MDVIP.
Ipsos, 202332% of US adults
say they actively try to consume probiotics, and among them 60% try to do so at least once a day, per a 2022 IFIC survey on gut health.
International Food Information Council, 202259 to 66 days
was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.
Systematic review and meta-analysis, 202461% to 74%
About 61 to 74 percent of adults refilling a long-term medicine on their own stopped within a year, versus 33 to 44 percent on one set pickup day.
Cohort study, 2015Meta-analysis, 2016
Across five combined trials, reishi mushroom taken alongside standard care raised the measured share of three types of immune cells by about 3.9, 3.1 and 2.0 percentage points.
Cochrane Database of Systematic ReviewsRandomised trial, 2005
Over eight weeks, a reishi polysaccharide extract lowered self-rated fatigue by about 28 percent from baseline versus 20 percent on placebo and raised the sense of well-being.
Journal of Medicinal FoodRandomised trial, 2024
Reishi supplementation was tested against placebo for self-reported psychological wellbeing, with modest changes on the questionnaire scores used.
International Journal of Medicinal MushroomsSystematic review, 2009
A systematic search of ten databases found the human research on maitake to be limited and clustered around glucose handling and immune stimulation, with the authors calling for randomised trials.
Journal of the Society for Integrative OncologyRandomised trial, 2024
In older women, 2,000 mg of reishi mushroom extract daily for eight weeks increased immune response to a lab stimulus and shifted immune markers toward an anti-inflammatory pattern versus placebo.
British Journal of NutritionRandomised trial, 2026
A randomised, double-blind trial of a multi-mushroom blend reported changes in self-rated stress, fatigue and sleep measures. Because the product was a blend, no result can be assigned to reishi alone.
Brain and BehaviorNarrative review, 2026
A review links mushroom intake, mainly as a source of vitamin D2 from UV light and trace minerals, to bone-related blood markers, but it's a summary, not a controlled trial.
PharmaceuticalsPopulation figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.
Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.
Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.
In a randomised, double-blind, placebo-controlled crossover in 12 recreationally active young men, a single 1 g dose of standardised Cordyceps militaris extract taken 30 minutes before a maximal cycling test was followed by faster Stroop reaction times across the session compared with placebo.
Two small studies measured a same-day effect. In a randomised, double-blind, placebo-controlled parallel-groups pilot in 41 healthy adults aged 18 to 45, a single 1.8 g dose of lion's mane was followed by quicker Stroop task performance at 60 minutes after dosing (p = 0.005). In a separate randomised, double-blind, placebo-controlled crossover study, a single 1 g dose of Nordic-grown lion's mane was followed by changes in working memory, complex attention and reaction time measures two hours after ingestion. Both samples are small. A third acute crossover in 18 adults using a 3 g dose of a 10:1 fruiting body extract found no effect on composite cognition or mood at 90 minutes, with a change only on an individual pegboard test.
Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.
7 ingredients, from each one's own page.
Work on fungal glucans is read from immune cell measurements and how often people report being run down, not from a same day sensation.
Give it three to four weeks of daily use. Any change shows up in how a hard session goes rather than as something you notice on the first day.
Before the calm side is noticeable. The immune side shows up in lab measures rather than in anything you sense.
Not an acute ingredient. Colonic fermentation starts within a day, while immune and glucose markers are read across four to eight weeks of daily use.
Before most people describe a cognitive change. Nothing about it behaves like a stimulant on day one.
Antioxidant and immune work with chaga reads on lab markers across four to eight weeks rather than as anything on the day.
Immune signalling shifts before anything is noticeable, so give it several weeks of daily use. Think in seasons rather than in days.
How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.
It is a capsule, so the amount per serving is fixed and travels without measuring.
Because the effect builds and holds only with continued daily use, a steady recurring supply is the practical way to keep it going.
Put an earned verification on your own product page.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.