Skip to main content
Verified by IngredientMD/Thorne/MediClear-SGS
VERIFIED BYingredientMD

MediClear-SGS.

Strong evidence, strong doseThorne, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Thorne.

Sulforaphane Glucosinolate is the lead active here, studied most for oxidative stress defence. 11 human studies on Sulforaphane Glucosinolate back this formula, each one cited. Each serving carries 250 mg of Vitamin C, inside the range the published research used. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
7Active ingredientsWell studiedResearch base71Human studies
MediClear-SGSVerified by IngredientMD
ThorneIngredientMD
The verdict
Strong evidence, strong dose
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Protein: Collagen and connective tissueSupporting role
Sulforaphane Glucosinolate: Oxidative stress defenceKey driver
Curcumin: Oxidative stress defenceWell studied
Green Tea Extract: Oxidative stress defenceWell studied
N-Acetyl Cysteine: Glutathione statusWell studied
Vitamin C: Oxidative stress defenceExtensively studied
B-Complex: MethylationExtensively studied

How we read this product

Source: Supplement facts
Supplement Facts panel for MediClear-SGS
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 7 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
71
Human studies
275 mg
Sulforaphane Glucosinolate
17 g
Protein
250 mg per serving sits inside the studied 200 mg-500 mg range
Curcumin, Daily 2016 meta + Amalraj 2017 bioavailability review
250 mg per serving sits inside the studied 200 mg-500 mg range
Vitamin C, Levine 1996 pharmacokinetics + NIH ODS

Cross-checked against 1,509 documented interactions for these actives.

Read the evidenceProtein, the evidence →Sulforaphane Glucosinolate, the evidence →Curcumin, the evidence →Green Tea Extract, the evidence →N-Acetyl Cysteine, the evidence →Vitamin C, the evidence →

Inside the formula

Protein
Collagen and connective tissue
Supporting role
Sulforaphane Glucosinolate
11 studies
Oxidative stress defence
Key driver
Curcumin
14 studies
Oxidative stress defence
Well studied
Green Tea Extract
17 studies
Oxidative stress defence
Well studied
N-Acetyl Cysteine
Glutathione status
Well studied
Vitamin C
20 studies
Oxidative stress defence
Studied 200 mg to 1 g a day
Extensively studied
B-Complex
Methylation
Extensively studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

The people it speaks toFieldwork 2024

17.0% of US adults

reported binge drinking or heavy drinking in 2024, above the levels the low-risk guideline defines, in the Behavioral Risk Factor Surveillance System.

CDC Behavioral Risk Factor Surveillance System, 2024
The people it speaks toFieldwork July 1 to 19, 2026

54% of US adults

say they drink alcohol, matching the record low set the previous year, in Gallup's Consumption Habits survey.

Gallup, 2026
The people it speaks toFieldwork July 1 to 19, 2026

US adults who drink average 3.2 drinks weekly

, down from an average of 3.9 drinks per week over prior years, in Gallup's Consumption Habits survey.

Gallup, 2026
29 more
The people it speaks to

US adults drank an average of 44 ounces

of plain water daily, in National Health and Nutrition Examination Survey data covering 2015 to 2018.

CDC, 2024
Daily use

59 to 66 days

was the median time it took adults to make a new daily health habit automatic across the studies a 2024 review pooled, with individuals ranging from 4 to 335 days.

Systematic review and meta-analysis, 2024
Curcumin

Meta-analysis, 2022

Across 10 randomised trials, curcumin taken around hard exercise lowered creatine kinase by about 66 IU/L, reduced muscle soreness ratings and widened joint range of motion by about 6.5 degrees.

Phytotherapy Research
Curcumin

Systematic review, 2026

An umbrella review found curcumin formulas eased knee pain and improved function scores in adults, most often using absorption-boosted versions.

Frontiers in medicine
Vitamin C

Meta-analysis, 2011

Across 13 trials, about 500 mg of vitamin C daily lowered blood uric acid by roughly 0.35 mg/dL.

The paper
Curcumin

Meta-analysis, 2025

In adults with raised blood sugar, turmeric or curcumin supplementation was linked to small reductions in body weight and waist circumference.

The paper
Vitamin C

Randomised trial, 2026

In repeated single-person trials, vitamin C raised blood levels by 20.6 micromol/L and lowered two stress markers, with day-to-day swings bigger than differences between people.

Free Radical Biology and Medicine
Vitamin C

Meta-analysis, 2014

Across 44 trials, vitamin C improved how well the blood vessel lining widens, a moderate effect of 0.50, larger at higher doses.

The paper
Ashor et al., 2014PMID 24792921
Curcumin

Meta-analysis, 2025

A network meta-analysis comparing nutritional supplements used for knee joint comfort, with curcumin among the compared entries and ranking uncertainty acknowledged by the authors.

Nutrients
Sulforaphane Glucosinolate

Randomised trial, 2021

In 10 young men, four weeks of daily sulforaphane lowered the rise in a muscle damage marker after heavy resistance exercise and reduced a related inflammation marker measured 30 minutes later.

Nutrition
Sulforaphane Glucosinolate

Randomised trial, 2026

Sixteen adults given mustard-seed myrosinase alongside broccoli seed extract doubled how much sulforaphane they absorbed, with vitamin C present in both study arms.

Scientific reports
Sulforaphane Glucosinolate

Randomised trial, 2025

In 74 adults with above-normal blood sugar, 12 weeks of a sulforaphane-yielding broccoli sprout extract lowered fasting blood sugar by about 0.2 mmol/L versus placebo, short of the trial's 0.3 mmol/L target.

Nature Microbiology
N-Acetyl Cysteine

Randomised trial, 2024

In a pilot trial in 165 adults with low vitamin D, adding L-cysteine to vitamin D for 6 months raised usable vitamin D levels and lowered inflammation markers compared with vitamin D alone.

BMJ Nutrition, Prevention and Health
N-Acetyl Cysteine

Randomised trial, 2025

Antioxidant supplementation with N-acetylcysteine was assessed against seminal parameters. The reported outcomes are semen analysis measures rather than clinical endpoints.

Archivio Italiano di Urologia e Andrologia
Sulforaphane Glucosinolate

Randomised trial, 2026

A study using detailed blood chemistry analysis in adults with reduced kidney filtering reported shifts in metabolite profiles after supplementation, a marker readout rather than a clinical outcome.

Food and Function
Vitamin C

Meta-analysis, 2012

Pooling 29 randomized trials, vitamin C at a median of 500 mg a day lowered systolic blood pressure by about 3.8 mmHg and diastolic by about 1.5 mmHg over a median of eight weeks.

American Journal of Clinical Nutrition
Sulforaphane Glucosinolate

Randomised trial, 2019

Across 170 adults over 10 days, the broccoli sprout beverage dose producing about 25 micromol of urinary sulforaphane metabolites a day raised urinary excretion of the benzene conjugate by 63.2%, while the one-half and one-fifth doses did not differ from placebo.

The American Journal of Clinical Nutrition
Curcumin

Meta-analysis, 2023

Pooling 66 randomised trials, curcumin or turmeric lowered C-reactive protein by about 0.58 mg/L, TNF-alpha by about 3.48 pg/mL and IL-6 by about 1.31 pg/mL, while IL-1 beta showed no detectable change.

Cytokine
N-Acetyl Cysteine

Randomised trial, 2020

In a small crossover trial in 19 healthy men given alcohol, 1,200 mg of L-cysteine was linked to less next-day nausea and headache, and 600 mg to lower stress and anxiety, on correlational analysis.

Alcohol and Alcoholism
Curcumin

Meta-analysis, 2025

Pooling trials, curcumin supplementation was linked to small improvements in overall cognitive performance in adults.

Frontiers in nutrition
N-Acetyl Cysteine

Randomised trial, 2019

N-acetylcysteine supplementation was associated with changes in functional connectivity measured by neuroimaging within the cingulate cortex. A brain imaging marker, not a symptom or functional outcome.

International Journal of Neuropsychopharmacology
Sulforaphane Glucosinolate

Randomised trial, 2024

In adults with reduced kidney filtration, sulforaphane supplementation did not produce a detectable change in the expression of two genes that govern antioxidant and inflammatory signalling, which is a failure to detect a difference rather than proof of none.

Journal of renal nutrition
N-Acetyl Cysteine

Randomised trial, 2022

Selenium, N-acetylcysteine, or both were compared against thyroid hormone marker changes in adults receiving haemodialysis. The endpoints are circulating markers, not clinical outcomes.

Pharmacology

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people20 human studies on Vitamin C back this formula, each one cited.
  • A mechanism that is settledHow Protein and Sulforaphane Glucosinolate work is settled pharmacology.
  • Studied together, not just separatelyProtein and Vitamin C have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2025.
  • Serving amount inside the studied rangeEach serving carries 250 mg of Vitamin C, inside the range the published research used.
  • A stated daily maintenance amountVitamin C is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
  • The exact form, describedThe label names its forms exactly: Bone broth protein powder, Stabilised sulforaphane, Turmeric extract standardised to 95 percent total curcuminoids. The record says what each one is and what it suits.
  • Where it comes from and how it is madeProtein is made by animal.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
How much it moves the numbers

The size of the effect, in plain numbers.

Where a trial measured an actual number, we show it next to the claim. It is the average across the trials, never a promise about one person.

Vitamin Crisk of developing a cold
Average change in the trials

About 52 percent lower risk of developing a cold, in trials of people undergoing brief periods of severe physical exertion.

Measured in
marathon runners, skiers and soldiers on subarctic exercises
Confidence interval
risk ratio 0.48, 95% CI 0.35 to 0.64

Read at the source. The magnitude sits beside the same trial the claim already cites. It describes what the trials measured, never what any one person will feel.

What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Curcuminmore than ten weeks of daily useBuilds with daily use

    A meta-analysis of randomised trials pooled nine trials for C reactive protein and 23 for high sensitivity C reactive protein in proinflammatory conditions. Pooled CRP fell by a weighted mean of 3.67 mg/L against placebo, and the subgroup analysis placed that fall in interventions running longer than ten weeks, with the high sensitivity CRP effect appearing in trials of ten weeks or less and at doses at or under 1,000 mg a day. An earlier meta-analysis of 19 trials in chronic inflammatory disease, with follow up of 4 to 16 weeks, found no significant change in CRP, hsCRP, IL-6 or TNF alpha. Heterogeneity was high across both reviews, and the measure is a blood marker rather than a symptom.

    Early
  • Green Tea Extractabout 12 weeks of daily useBuilds with daily use

    In a 12-week randomised, double-blind, placebo-controlled trial, 80 middle-aged adults with self-reported memory complaints took heat-treated green tea extract or placebo. The extract group showed a greater improvement in a standardised composite memory score at week 12, alongside increased functional connectivity within the default mode network on imaging. One trial of 80 people, in a population with subjective complaints rather than measured impairment.

    Promising
  • Vitamin Cwithin 24 hours of a single doseMeasured within a day

    In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

    Strong

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

7 ingredients, from each one's own page.

1 more

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • L-cysteine

    The free amino acid with an unprotected thiol group, a white crystalline solid.

    Fits
    Food processing and formulations where the underivatised amino acid is specified.
    Trade-off
    The free thiol oxidises to cystine on exposure to air and in solution, so it needs protective packaging and is not stable in liquids.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.

Best forGram-scale actives: creatine, collagen, protein, electrolytes, beta-alanine.
From the same shelf

Studied alongside this brand's other formulas

Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.

Questions shoppers ask

Is MediClear-SGS independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in MediClear-SGS?
MediClear-SGS is built on Protein, Sulforaphane Glucosinolate, Curcumin, Green Tea Extract, N-Acetyl Cysteine, Vitamin C, and more. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 1,509 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?

Put an earned verification on your own product page.

Get verified

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

Independent review by IngredientMD, not commissioned by ThorneWork at Thorne? This verification is yours to claim →