Cross-referencing clinical data
A pairing appears on this page only when a trial gave both ingredients together and measured the result. Dense Fruit Dittany has none that clears that bar.
Stitching two separate single-ingredient studies into a pairing is the one thing this engine will not do. When a study of the combination itself holds up at source, it lands here with its citation.
No invented synergy. Where actives were studied on their own rather than together, the record shows each on its own evidence, never a combined effect no trial measured.
Research strength. Research strength says how much work stands behind the combination. It is never a product score.
Independent record. Every finding is cited to a named trial, dated, and never written by the brand.
20 pairings are live across the library today. Checked 20 July 2026.
No study gave these as a pair, so they are not in the card above. But the reason they belong together is settled biochemistry, not a guess, so it is worth knowing.
Cortex Dictamni is a bitter, cold herb in classical practice and is customarily combined with licorice root as a harmonising agent in skin-directed formulas. The pairing is convention rather than a measured interaction, and no controlled human data quantify what licorice contributes. Licorice also carries its own mineralocorticoid-like effect at sustained intakes, which is the more relevant consideration for anyone taking both. Read this as ethnobotanical context, not as evidence of added benefit.
Dittany root bark is paired with dang gui in traditional formulas aimed at skin dryness and itching, where the two are held to balance each other's temperature and moisture properties. This is a documented compounding habit with centuries of use behind it and essentially no modern trial data. Both plants can affect bleeding tendency and hepatic handling, so co-use is a monitoring point rather than a free addition.
People sometimes stack a liver-supportive extract alongside dittany root bark because of its adverse-event record. Silymarin does not neutralise that record, and adding it should not be read as licence to use dittany at higher doses or for longer. The sensible framing is that anyone using dittany root bark for more than a short course warrants liver enzyme checks regardless of what else is in the bottle. No trial has tested the combination in humans.
St John's wort contains hypericin, an established photosensitiser, and dittany root bark contributes furoquinoline alkaloids from the same broad photoreactive family. Taking both raises the plausible combined burden on sun-exposed skin. This is a mechanistic expectation from the chemistry of both plants rather than a documented clinical event series. Anyone combining them has good reason to be conservative about ultraviolet exposure.
Both botanicals appear in case reporting of transaminase elevation, curcumin far more often in Western datasets and Dictamnus more often in East Asian ones. Case reports are the weakest human evidence design and do not establish that either plant causes the finding in a given person. Still, stacking two botanicals that share the same reported signal is worth flagging rather than ignoring.
Nothing specific on file for Dense Fruit Dittany. Match the label to the daily amount above, and tell your doctor what you take.
Not medical advice. Show the label to your pharmacist.FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.