Womens Balance.

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

• Studied in people22 human studies on Zinc back this formula, each one cited.
• A mechanism that is settledHow Vitamin A (as Beta-Carotene) and Vitamin C work is settled pharmacology.
• Studied together, not just separatelyVitamin A (as Beta-Carotene) and Vitamin C have been studied together, not only separately.
• Recent work on the recordThe most recent study on this record was published in 2026.
• Serving amount inside the studied rangeEach serving carries 2,500 mcg of Biotin, inside the range the published research used.
• A stated daily maintenance amountBiotin is here at a daily maintenance amount, which is what a daily supplement is for.
• Why this formatIt is a capsule, so the amount per serving is fixed and travels without measuring.
• The exact form, describedThe label names its forms exactly: Beta-carotene, Ascorbic acid, Vitamin D3 in a carrier oil, lanolin-derived. The record says what each one is and what it suits.
• An absorption partner in the same servingBlack Pepper (Fruit) Extract is in the same serving as Hydrolyzed Marine Collagen Type I & III, where it has a measured absorption role.
• A declared blend totalSYNERGEN COMPLEX PLUS declares its total, 1,875 mg per serving, with 7 ingredients listed by weight.
• Where it comes from and how it is madeVitamin A (as Beta-Carotene) is made by more than one route.
• Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
• A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
• Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.

The combinations the trials actually measured.

Two pairings in this formula have been studied as combinations in human trials. Each finding below is what a named study measured, cited and dated, never written by the brand.

• Organic Gelatinized Maca (Root) Powder + Vitamin CRecovery

  In a randomized crossover trial, 15 g of vitamin C-enriched gelatin taken an hour before exercise roughly doubled a blood marker of collagen synthesis compared with placebo.

  Shaw et al., 2017 (Am J Clin Nutr)PMID 27852613

  Early
• Zinc + SeleniumImmune

  In a two-year trial in older adults, zinc taken together with selenium improved the antibody response to influenza vaccination.

  Girodon et al., 1999 (Arch Intern Med)PMID 10218756

  Early

Findings from trials that studied these actives as a combination. Context for how the actives were tested together, not a statement about any individual and not a claim about this product.

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

• Vitamin Cwithin 24 hours of a single doseMeasured within a day

  In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

  Choi et al., 2025 (Nutrients)PMID 41228404

  Strong
• Vitamin D3about 3 months of daily useBuilds with daily use

  In the trial record, blood vitamin D rises for about 3 months of daily vitamin D3 and then holds at a plateau, near 69 nmol/L at 1,000 IU a day, from a starting level near 41 nmol/L.

  Vieth et al., 2001 (Am J Clin Nutr)PMID 11157326

  Early
• Vitamin Eabsorbed slowly, tracked over 72 hoursMeasured within a day

  In a 3-phase crossover using two deuterium-labelled forms of alpha-tocopherol, healthy women absorbed about 55 percent of an oral dose taken with a 40 percent fat meal and about 64 percent with a fat-free meal, with samples tracked over 72 hours. The authors conclude absorption is not limited by absent fat or fasting, and that vitamin E leaves the intestine by a prolonged process.

  Traber et al., 2019 (American Journal of Clinical Nutrition)PMID 31495886

  Promising
• Biotinabout 5 to 6 months of daily useBuilds with daily use

  In an open trial with no placebo arm, 71 patients with brittle or splitting fingernails took 2.5 mg of biotin a day. Of the 45 cases that could be evaluated, 41 were rated as having firmer and harder nails after an average of 5.5 months of treatment, standard deviation 2.3 months. The rating was clinical judgement rather than an instrument reading, and there was no control group, so the window describes when the raters recorded change, not a placebo adjusted effect.

  Floersheim, 1989 (Z Hautkr)PMID 2648686

  Early
• Iodine (from Organic Kelp)from about eight weeks, deepening through twenty-four weeksBuilds with daily use

  In a 24 week randomised double-blind placebo-controlled trial in 112 mildly iodine-deficient New Zealand adults aged 18 to 40, 150 micrograms of iodine a day as potassium iodate lowered thyroglobulin, a blood marker of iodine status, by 12 percent at 8 weeks, 20 percent at 16 weeks and 27 percent at 24 weeks compared with placebo. Median urinary iodine reached 168 micrograms per litre against 79 on placebo. TSH and free T4 stayed within normal range and did not change significantly.

  Ma and colleagues 2016, Journal of Clinical Endocrinology and MetabolismPMID 26891118

  Promising
• Zincover about five days of lozenges started within 24 hours of symptom onsetBuilds with daily use

  Across three randomised placebo-controlled trials pooled as individual patient data (199 adults with naturally acquired colds, 80 to 92 mg of elemental zinc a day as acetate lozenges), 70 percent of the zinc group had recovered by day 5 against 27 percent on placebo, and colds ran 2.73 days shorter against a 7 day average duration. A separate meta-analysis of seven lozenge trials (575 participants, doses above 75 mg a day, zinc acetate or zinc gluconate) measured cold duration 33 percent shorter, with no significant difference between the two salts.

  Hemilä et al., 2017 (Open Forum Infect Dis)PMID 28480298

  Hemilä et al., 2016 (Br J Clin Pharmacol)PMID 27378206

  Hemilä, 2017 (JRSM Open)PMID 28515951

  Strong

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

How each ingredient usually behaves over time.

12 ingredients, from each one's own page.

• Vitamin A (as Beta-Carotene)Weeks, not days

  Weeks to months. It is a status ingredient, so the change turns up in plasma carotenoid and retinol readings rather than in anything day to day.

  Its own page, the plain answer on timing ↗

• Vitamin CWithin hours

  Blood levels rise within hours and tissue pools fill over days. Collagen-linked changes in skin and gums build over weeks and show as tissue quality, not as a sensation.

  Its own page, the plain answer on timing ↗

• Vitamin D3About six to twelve weeks

  25-hydroxyvitamin D climbs over roughly six to twelve weeks of daily dosing before it plateaus. It's a blood level you watch rather than a feeling.

  Its own page, the plain answer on timing ↗

• Vitamin EWeeks, not days

  Plasma alpha-tocopherol climbs within days of daily intake, and anything you'd notice in skin condition is a slow change across a couple of months.

  Its own page, the plain answer on timing ↗

• BiotinAbout 8 to 12 weeks

  Fingernails grow around 3mm a month, so it takes roughly 8 to 12 weeks before enough new plate has grown out to judge the difference by eye.

  Its own page, the plain answer on timing ↗

• Iodine (from Organic Kelp)Weeks, not days

  Thyroid hormone turns over slowly, so the change lands on a urinary iodine measure and a thyroid panel before it lands anywhere in your day.

  Its own page, the plain answer on timing ↗

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

• Beta-carotene

  Chemically synthesised crystalline carotene, essentially a single all-trans isomer of high purity.

  Fits

  Standardised supplement and fortification use where a consistent, defined isomer content is wanted.

  Trade-off

  It supplies one isomer rather than the mixture found in a plant source, and the crystal needs a delivery system to be dispersible at all.

• Cholecalciferol (vitamin D3)

  The animal-sourced form of vitamin D, made in skin under UVB light and produced commercially from lanolin. Fat-soluble, so it travels with dietary fat and is stored in body fat.

  Fits

  Raising and holding vitamin D status, and the form most supplement trials use.

  Trade-off

  Being fat-soluble it accumulates with sustained high dosing, so intakes are set against the tolerable upper level rather than topped up freely.

  In a 12-week double-blind randomised controlled trial in 108 young women in urban Bangalore, most of whom began vitamin D-deficient, daily vitamin D3 at 400, 600 or 800 IU in a fortified wafer raised serum 25-hydroxyvitamin D, parathyroid hormone fell over time, and effects on bone-turnover markers were modest and not dose specific. The 800 IU dose brought 65 percent of participants to sufficiency.

  Peris et al., 2026 (Nutrients)PMID 42124077
• Kelp (seaweed-sourced iodine)

  Dried, milled brown seaweed such as Ascophyllum nodosum or Laminaria, in which iodine occurs naturally bound within the plant tissue alongside other marine minerals.

  Fits

  A whole-food marine source that suits formulas positioned around natural or food-derived ingredients rather than isolated salts.

  Trade-off

  The iodine content of seaweed varies widely with species, harvest and season, so unless a batch is standardised the delivered amount is hard to pin down, and kelp can also carry other elements taken up from seawater.

• L-lysine (free-form)

  The lysine amino acid with no acid counter-ion attached, sold as the base itself. Because there is no added salt mass, a stated weight corresponds more closely to pure lysine than the equivalent weight of a salt.

  Fits

  Suits formulas that want the panel figure to line up with the amino acid itself, with no chloride or acetate to account for, and blends where an added counter-ion is unwanted.

  Trade-off

  The free base is more hygroscopic and less crystalline-stable to handle than the hydrochloride, so it can be harder to keep free-flowing in a powder or to press cleanly into a tablet, which is why standalone products often reach for the salt instead.

• L-methionine (free-form)

  The single L-enantiomer (S-configuration) of the sulfur-containing essential amino acid methionine, molecular formula C5H11NO2S, supplied as the free amino acid rather than as a salt, ester or chelate. It is the proteinogenic stereoisomer of methionine and is typically made by fermentation.

  Fits

  Matches the L-enantiomer proteins are built from, so it needs no isomer conversion step. A clean single-ingredient choice for standalone amino acid products and for free-amino-acid blends where a defined L-form is specified on the panel.

  Trade-off

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Capsule

It is a capsule, so the amount per serving is fixed and travels without measuring.

Studied alongside this brand's other formulas

Where two of this brand's products carry actives the literature has read together, the pairing and its basis are below. The evidence word is the corpus row's own confidence, never a score.