Ingredients / Probiotic / Lactobacillus Casei DN-114001

Lactobacillus Casei DN-114001.

Lactobacillus Casei DN-114001 supplementation for targeted health support.

Quick readUpdated Mar 26

Overall rating7.0/10

EvidenceGrade B+

Studies40+

Daily dose20,000,000 CFU

Norans Kepals · Independent Researcher · Verified Mar 26

8 things →Breakdown →Science →

Most askedWhat people google before scrolling

Is this the Actimel/DanActive strain?

Yes. DN-114001 is Danone's proprietary strain used in these products since the 1990s.

Does it actually reduce colds?

Studies show reduced duration of common respiratory infections by about a day on average. Not prevention, but faster recovery.

Why company-sponsored research?

Probiotic research is expensive. Companies fund studies on their strains. Quality varies but DN-114001 research is generally decent.

No-BS summary

Eight things. Sixty seconds.

Everything you need
before you scroll further

What it does

A Lactobacillus casei strain that supports gut barrier function, may reduce duration of common infectious illnesses, and contributes to healthy gut microbiome.

Does it work?

8/10. Well-researched with consistent findings. The delivery in functional dairy makes it convenient. Studies show real immune benefits. Company-sponsored research but still useful.

Click through to the studies bar for the evidence base.

How much

10+ billion CFU daily. Typically provided in probiotic dairy drinks at this level.

See the dosing guide below.

Cost

$15-30/month via functional dairy products.

Compare formats before buying.

First 24 hours

Nothing noticeable.

Some ingredients build up over weeks. Others act fast.

After weeks

Studies show reduced duration of common respiratory and GI infections. Improved gut health markers.

The compound effect of consistent dosing.

Safety

Excellent. Probiotics in general and this strain specifically have excellent safety records.

Check the cautions section if you have a pre-existing condition.

How it feels

Subtle. Better digestive regularity, possibly fewer sick days over a season.

Some ingredients you feel. Others just work in the background.

The breakdown

If you're still curious.

Quick answers · dose curve
Forms · food sources

Is it available as a supplement?

Mainly in Danone dairy products. Less commonly available as standalone capsules. The dairy delivery may actually help survival.

How does it compare to other L. casei strains?

Strain-specific. Different L. casei strains have different effects. DN-114001's research may not apply to generic L. casei.

Is daily dairy necessary?

The studied delivery is daily consumption. Consistency matters for probiotic benefits.

Dose-response curve.

How effective at different doses · % saturation

0–39%

Sub-therapeutic

< 5000000000.0g

39–81%

Effective

5000000000.0–20000000000.0g

~81%

Optimal

20000000000.0g

81%

Diminishing

> 50000000000.0g

Bottom line

20000000000.0g is the number.

Most research uses 20000000000.0g daily. Below 5000000000.0g, you're probably wasting money. Above 50000000000.0g, no extra benefit. The curve plateaus. Safe upper limit ~ 100000000000.0g.

Source · Based on clinical studies using Actimel/DanActive products.

Dosing guide. When · how · with food · formsQuick reference

When

As directed

Consistency > timing. Pick a slot you'll keep.

How much

As directed

One scoop. Every day.

With food

With or without food

Check the section above on absorption.

Forms

From food.

Want to skip the supplement? Here's what you'd need from food to match a daily dose.

Daily intake from food

Actimel/DanActive

1 bottle daily

Reality check

Probiotic dairy. The primary delivery method. Each bottle contains the researched dose.

USDA FoodData Central · daily-intake estimates

Deep dive

The science.

For those who want
the full picture

40+ studies analyzed

Grade B+ evidence.

Human trials

Meta-analyses

Key claims, fact-checked.

Reduces infection duration

Multiple studies show reduced duration of common infections

Likely

Supports gut health

Consistent probiotic mechanism and studies

Likely

Survives to reach gut

Designed and tested for acid survival

Proven

Safe for daily use

Decades of commercial use

Proven

In one paragraph

Lactobacillus Casei DN-114001 has emerging evidence.

Origins & manufacturing.

Natural sources

Isolated and developed by Danone research

If you take this · stack it

Run it through the stack.

Lactobacillus Casei DN-114001 interacts with other supplements and meds. The analyzer flags interactions, dose mismatches, and timing collisions across your whole list.

One primary action
· no secondary CTAs
Analyze my stack →

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.