AG1.

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

• Studied in people22 human studies on Zinc back this formula, each one cited.
• A mechanism that is settledHow Vitamin A and Vitamin C work is settled pharmacology.
• Studied together, not just separatelyVitamin A and Vitamin E have been studied together, not only separately.
• Recent work on the recordThe most recent study on this record was published in 2026.
• Serving amount inside the studied rangeEach serving carries 420 mg of Vitamin C, inside the range the published research used.
• A stated daily maintenance amountVitamin C is here at a daily maintenance amount, which is what a daily supplement is for.
• Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
• The exact form, describedThe label names its forms exactly: Retinyl palmitate, Ascorbic acid, d-alpha-tocopherol (natural). The record says what each one is and what it suits.
• An absorption partner in the same servingZinc is in the same serving as Inulin (FOS prebiotics), where it has a measured absorption role.
• A declared blend totalAlkaline, Nutrient-Dense Raw Superfood Complex declares its total, 7,388 mg per serving, with 22 ingredients listed by weight.
• Where it comes from and how it is madeVitamin A is made by more than one route.
• Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
• A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
• Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.

The combinations the trials actually measured.

Four pairings in this formula have been studied as combinations in human trials. Each finding below is what a named study measured, cited and dated, never written by the brand.

• Zinc + SeleniumImmune

  In a two-year trial in older adults, zinc taken together with selenium improved the antibody response to influenza vaccination.

  Girodon et al., 1999 (Arch Intern Med)PMID 10218756

  Early
• Calcium + MagnesiumStrength

  In a 12-month randomised, double-blind trial, 98 adults aged 50 and over drank a litre a day of either a naturally calcium- and magnesium-rich mineral water or a low-mineral water. The mineral-rich group had fewer falls at the 6-month assessment and higher appendicular muscle mass, with the minerals delivered as drinking water rather than a capsule.

  Moretti et al., 2026 (Nutrients)PMID 41683292

  Promising
• Folate + Vitamin B12 + Vitamin B6Heart

  In a 2025 network meta-analysis of 16 randomized trials in healthy adults, folic acid taken together with vitamins B6 and B12 lowered blood homocysteine more than any single supplement, with the 1 mg folic acid plus 7.2 mg B6 plus 20 micrograms B12 arm ranked most effective versus placebo (mean difference -1.03 micromol/L, 95% CI -1.71 to -0.36).

  Liu et al., 2025 (Nutrition Reviews)PMID 39960689

  Promising
• Magnesium + Vitamin B6Calm

  In an 8-week randomized trial of 264 stressed healthy adults with low magnesium, magnesium plus vitamin B6 and magnesium alone reduced perceived stress about equally overall. In the prespecified subgroup that started with severe stress, the combination improved stress scores 24% more than magnesium alone.

  Pouteau et al., 2018 (PLoS One)PMID 30562392

  Early

Findings from trials that studied these actives as a combination. Context for how the actives were tested together, not a statement about any individual and not a claim about this product.

The size of the effect, in plain numbers.

Where a trial measured an actual number, we show it next to the claim. It is the average across the trials, never a promise about one person.

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

• Vitamin Cwithin 24 hours of a single doseMeasured within a day

  In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

  Choi et al., 2025 (Nutrients)PMID 41228404

  Strong
• Vitamin Eabsorbed slowly, tracked over 72 hoursMeasured within a day

  In a 3-phase crossover using two deuterium-labelled forms of alpha-tocopherol, healthy women absorbed about 55 percent of an oral dose taken with a 40 percent fat meal and about 64 percent with a fat-free meal, with samples tracked over 72 hours. The authors conclude absorption is not limited by absent fat or fasting, and that vitamin E leaves the intestine by a prolonged process.

  Traber et al., 2019 (American Journal of Clinical Nutrition)PMID 31495886

  Promising
• Thiamin (Vitamin B1)about 18 to 30 days of restricted intakeBuilds with daily use

  In the controlled depletion study the EFSA reference opinion reviews, restricting thiamin intake to 0.009 to 0.015 mg/MJ for 30 days brought urinary free thiamin excretion from a mean of 0.283 mg/24 h down to undetectable levels by day 18 of the depletion period.

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), 2016 (EFSA Journal)PMID 42006014

  Promising
• Thiamin (Vitamin B1)about 1 week of renewed intakeBuilds with daily use

  In the same depletion and repletion record the EFSA reference opinion reviews, erythrocyte transketolase activity fell progressively to about 75% of baseline during the 30-day depletion period and returned to its baseline value after 1 week of thiamin repletion.

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), 2016 (EFSA Journal)PMID 42006014

  Promising
• Riboflavin (Vitamin B2)about 8 weeks of daily intakeBuilds with daily use

  In an intervention the EFSA reference opinion reviews, adults whose baseline riboflavin intake and status were unknown received 5 mg/day of riboflavin for 8 weeks, and haemoglobin concentration, haematocrit and erythrocyte count all rose significantly over that period.

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), 2017 (EFSA Journal)PMID 32625611

  Early
• Vitamin B6about 20 to 40 days to clear after stoppingBuilds with daily use

  An expert consensus on vitamin B6 use, developed by a six-member Delphi panel with a structured evidence-quality assessment, calculated from pharmacokinetic parameters that complete clearance of vitamin B6 from the body takes a washout period of about 20 to 40 days after intake stops.

  Schellack et al., 2025 (Drug Healthc Patient Saf)PMID 40395441

  Early

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

How each ingredient usually behaves over time.

12 ingredients, from each one's own page.

• Vitamin AWeeks, not days

  Weeks to months. Liver stores buffer intake, so vitamin A status moves slowly and shows up on a blood panel rather than as a sensation.

  Its own page, the plain answer on timing ↗

• Vitamin CWithin hours

  Blood levels rise within hours and tissue pools fill over days. Collagen-linked changes in skin and gums build over weeks and show as tissue quality, not as a sensation.

  Its own page, the plain answer on timing ↗

• Vitamin EWeeks, not days

  Plasma alpha-tocopherol climbs within days of daily intake, and anything you'd notice in skin condition is a slow change across a couple of months.

  Its own page, the plain answer on timing ↗

• Thiamin (Vitamin B1)

  There is no onset to time in the usual sense. Status markers such as erythrocyte transketolase activity move across weeks, and that is where the change is read.

  Its own page, the plain answer on timing ↗

• Riboflavin (Vitamin B2)Within hours

  Urine turns bright yellow within hours of the first dose. Status itself, read as red cell glutathione reductase activity, shifts across two to eight weeks.

  Its own page, the plain answer on timing ↗

• Niacin

  Nothing to wait for at everyday amounts. Niacin status shows up on blood work rather than as a sensation. The flush from the nicotinic acid form arrives within 30 minutes.

  Its own page, the plain answer on timing ↗

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

• Riboflavin

  The free vitamin B2 molecule, an isoalloxazine ring joined to a ribitol sugar chain, supplied as the unmodified crystalline compound with no added salt or phosphate group.

  Fits

  It is the form most panels list simply as riboflavin or vitamin B2.

  Trade-off

  It is intensely yellow and only sparingly water soluble, so it can tint a finished product and tends to resist dissolving cleanly in a liquid or a fast-melt format.

• Nicotinic acid

  The free-acid form of vitamin B3, pyridine-3-carboxylic acid. It is the reference form of niacin, a small water-soluble molecule carrying a bare carboxylic acid group on the pyridine ring.

  Fits

  The long-standing reference form for meeting a vitamin B3 requirement.

  Trade-off

  This is the form behind the familiar warm, tingling skin flush that many people notice soon after a larger dose, a recognized property of the free acid that leads some formulators to reach for an amide or ester instead.

• D-pantothenic acid

  The free acid form of vitamin B5, an amide of pantoic acid and beta-alanine, supplied as a viscous hygroscopic oil or a stabilised liquid rather than a dry salt.

  Fits

  The un-neutralised acid carries no mineral counterion, so it suits liquid drops, syrups and formats where a calcium or sodium salt is not wanted.

  Trade-off

  It is hygroscopic and tends to draw water and turn sticky, which makes it awkward to hold as a dry powder without added stabilisers.

• Wheat grass juice powder

  The pressed liquid fraction of young wheat grass, dried to a fine soluble powder with the insoluble pulp removed.

  Fits

  Suited to drinks that need to dissolve cleanly and to formulas where insoluble fibre is not wanted.

  Trade-off

  The fibre and some of the cell wall bound constituents are discarded with the pulp, and yield per kilogram of fresh grass is low, which raises cost per gram.

• Broccoli flower powder

  Whole floret tissue dried and reduced to a powder, carrying glucoraphanin at native food-level concentration along with fibre, vitamin C and vitamin K1.

  Fits

  Whole-food green blends and powders where the intent is food material rather than a standardised compound.

  Trade-off

  Native glucoraphanin concentration is low, so a blend-level scoop delivers a small amount, and drying heat determines whether any myrosinase activity survives.

• Licorice root powder

  The milled dried root and stolon, carrying glycyrrhizin at a variable natural level along with the full flavonoid and polysaccharide fraction.

  Fits

  Teas, decoctions and traditional-style capsules where the whole root is wanted.

  Trade-off

  Glycyrrhizin content is not fixed, so the amount per gram varies with origin, species and harvest year.

4 more

Slippery elm bark powder

Dried inner bark ground fine, holding mucilage in its native matrix along with bark fibre, tannins and phenolics.

Fits

Drink mixes, gruels and lozenge bases where the hydrated gel texture is the point of the format.

Trade-off

Thickens fast in liquid, so larger servings are difficult to drink and need plenty of water.

Kelp (seaweed-sourced iodine)

Dried, milled brown seaweed such as Ascophyllum nodosum or Laminaria, in which iodine occurs naturally bound within the plant tissue alongside other marine minerals.

Fits

A whole-food marine source that suits formulas positioned around natural or food-derived ingredients rather than isolated salts.

Trade-off

The iodine content of seaweed varies widely with species, harvest and season, so unless a batch is standardised the delivered amount is hard to pin down, and kelp can also carry other elements taken up from seawater.

BSAFormulation aid

Albumin fractionated from bovine plasma, used as a defined protein reagent with characterised binding sites.

Fits

Laboratory and cell culture applications, and preservation media.

Trade-off

Lot to lot protein background varies with the source plasma, and it is an animal blood-derived material rather than a food ingredient.

Pea protein isolate

Wet-fractionated protein, typically 80 percent or more protein by weight, with starch, most fibre and much of the phytate removed by isoelectric precipitation.

Fits

Shakes and ready-to-mix powders where protein density per scoop is the point.

Trade-off

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.