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Verified by IngredientMD/Athletic Greens/AG1 Athletic Greens
VERIFIED BYingredientMD

AG1 Athletic Greens.

Strong evidence, strong doseAthletic Greens, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Athletic Greens.

Vitamin C is the lead active here, studied most for iron status. 20 human studies on Vitamin C back this formula, each one cited. Each serving carries 400 mg of Vitamin C, inside the range the published research used. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
88Active ingredientsWell studiedResearch base706Human studies
AG1 Athletic GreensVerified by IngredientMD
Athletic GreensIngredientMD
The verdict
Strong evidence, strong dose
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Vitamin A: Filling everyday nutrient gapsExtensively studied
Vitamin C: Iron statusKey driver
Vitamin D3: Filling everyday nutrient gapsExtensively studied
Vitamin E: Filling everyday nutrient gapsWell studied
Vitamin K: Filling everyday nutrient gapsExtensively studied
Thiamin: Filling everyday nutrient gapsExtensively studied
Riboflavin: Filling everyday nutrient gapsExtensively studied
Niacin: Filling everyday nutrient gapsWell studied
Vitamin B6: Filling everyday nutrient gapsSupporting role
Folate: MethylationExtensively studied
Vitamin B12: Vitamin B12 statusExtensively studied
Biotin: Filling everyday nutrient gapsWell studied
Pantothenic Acid: Filling everyday nutrient gapsWell studied
Choline: Choline statusExtensively studied
Calcium: Filling everyday nutrient gapsExtensively studied
Phosphorus: Filling everyday nutrient gapsWell studied
Iodine: Iodine statusExtensively studied
Magnesium: Magnesium statusExtensively studied
Zinc: Filling everyday nutrient gapsExtensively studied
Selenium: Filling everyday nutrient gapsExtensively studied
Copper: Filling everyday nutrient gapsWell studied
Manganese: Filling everyday nutrient gapsWell studied
Chromium: Filling everyday nutrient gapsWell studied
Molybdenum: Filling everyday nutrient gapsWell studied
Sodium: HydrationWell studied
Potassium: Filling everyday nutrient gapsExtensively studied
Nutritive, Nutrient Dense Raw Superfood Complex: A 7732 mg blend of 35 ingredients, listed by weight.Supporting role
Organic Alfalfa (aerial parts): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed first.Supporting role
Organic Spirulina (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed second.Well studied
Organic Chlorella (cracked cell wall): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed third.Well studied
Organic Wheat Grass (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed fourth.Supporting role
Organic Barley Grass (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed fifth.Supporting role
Organic Oat Grass (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed sixth.Supporting role
Organic Broccoli (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed seventh.Supporting role
Organic Spinach (whole plant): Methylation. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed eighth.Supporting role
Organic Kale (whole plant): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed ninth.Supporting role
Organic Beet (root): Methylation. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed tenth.Well studied
Organic Carrot (root): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 11th.Supporting role
Organic Apple (fruit): Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 12th.Supporting role
Organic Blueberry (fruit): A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 13th.Supporting role
Organic Raspberry (fruit): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 14th.Supporting role
Organic Strawberry (fruit): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 15th.Supporting role
Organic Acai (fruit): A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 16th.Supporting role
Organic Pomegranate (fruit): A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 17th.Well studied
Organic Cranberry (fruit): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 18th.Supporting role
Organic Goji Berry (fruit): Iron status. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 19th.Well studied
Organic Acerola Cherry (fruit): Iron status. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 20th.Supporting role
Organic Ginger (root): Regularity. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 21th.Extensively studied
Organic Turmeric (root): Part of this formula. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 22th.Supporting role
Organic Milk Thistle (seed): Everyday liver support. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 23th.Well studied
Organic Dandelion (root): Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 24th.Supporting role
Organic Green Tea (leaf): Oxidative stress defence. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 25th.Well studied
Organic Peppermint (leaf): Comfort after a heavy meal. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 26th.Supporting role
Organic Rosemary (leaf): Feeding the bacteria that make butyrate. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 27th.Well studied
Organic Sage (leaf): Feeding the bacteria that make butyrate. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 28th.Well studied
Organic Thyme (leaf): Oxidative stress defence. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 29th.Supporting role
Organic Cinnamon (bark): Breaking down what you eat. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 30th.Well studied
Organic Licorice (root): Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 31th.Well studied
Organic Fennel (seed): Comfort after a heavy meal. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 32th.Supporting role
Organic Clove (bud): Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 33th.Supporting role
Organic Black Pepper (fruit): Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 34th.Well studied
Organic Cayenne Pepper (fruit): Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 35th.Well studied
Nutrient Dense Herbs, Extracts & Antioxidants: A 2732 mg blend of 13 ingredients, listed by weight.Supporting role
Moringa (leaf): Filling everyday nutrient gaps. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed first.Well studied
Citrus Bioflavonoids (fruit): Filling everyday nutrient gaps. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed second.Well studied
Rhodiola (root) extract: Energy without a stimulant. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed third.Extensively studied
Ashwagandha (root) extract: Everyday stress. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed fourth.Extensively studied
Ginseng (root) extract: Energy without a stimulant. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed fifth.Well studied
Green Coffee Bean (seed) extract: Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed sixth.Well studied
Grape Seed (seed) extract: Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed seventh.Well studied
Alpha Lipoic Acid: Glutathione status. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed eighth.Well studied
Coenzyme Q10: Cellular energy production. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed ninth.Extensively studied
Resveratrol (root) extract: Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed tenth.Well studied
Lutein: Eye health. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 11th.Extensively studied
Zeaxanthin: Eyes under bright screen light. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 12th.Well studied
Lycopene: Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 13th.Well studied
Digestive Enzymes & Super Mushroom Complex: A 100 mg blend of eight ingredients, listed by weight.Well studied
Amylase: Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed first.Well studied
Protease: Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed second.Supporting role
Lipase: Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed third.Well studied
Cellulase: Filling everyday nutrient gaps. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed fourth.Supporting role
Lactase: Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed fifth.Extensively studied
Reishi Mushroom (fruiting body) extract: A balanced gut microbiome. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed sixth.Well studied
Shiitake Mushroom (fruiting body) extract: Vitamin D status. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed seventh.Well studied
Maitake Mushroom (fruiting body) extract: Vitamin D status. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed eighth.Well studied
Dairy Free Probiotic T20 CFU: A 50 mg blend of two ingredients, listed by weight.Supporting role
Lactobacillus acidophilus (LA-02): Comfort after dairy. In the 50 mg Dairy Free Probiotic T20 CFU with one other, listed first.Well studied
Bifidobacterium lactis (BL-04): Feeding the bacteria that make butyrate. In the 50 mg Dairy Free Probiotic T20 CFU with one other, listed second.Well studied

How we read this product

Source: Supplement facts
Supplement Facts panel for AG1 Athletic Greens
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 88 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Strong evidence, strong dose".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
706
Human studies
400 mg
Vitamin C
500 mcg
Vitamin A
400 mg per serving sits inside the studied 200 mg-500 mg range
Vitamin C, Levine 1996 pharmacokinetics + NIH ODS
120 mcg per serving sits inside the studied 90 mcg-120 mcg range
Vitamin K, NIH ODS
2 mg per serving sits inside the studied 1 mg-50 mg range
Thiamin, NIH ODS + Lonsdale 2006 review
2 mg per serving sits inside the studied 1 mg-25 mg range
Riboflavin, NIH ODS + Schoenen 1998

Cross-checked against 8,931 documented interactions for these actives.

Read the evidenceVitamin A, the evidence →Vitamin C, the evidence →Vitamin D3, the evidence →Vitamin E, the evidence →Vitamin K, the evidence →Thiamin, the evidence →

Inside the formula

Vitamin A
Filling everyday nutrient gaps
Extensively studied
Vitamin C
20 studies
Iron status
Studied 200 mg to 1 g a day
Key driver
Vitamin D3
20 studies
Filling everyday nutrient gaps
Extensively studied
Vitamin E
15 studies
Filling everyday nutrient gaps
Well studied
Vitamin K
11 studies
Filling everyday nutrient gaps
Studied 90 mcg to 500 mcg a day
Extensively studied
Thiamin
11 studies
Filling everyday nutrient gaps
Extensively studied
Riboflavin
10 studies
Filling everyday nutrient gaps
Studied 1.3 mg to 100 mg a day
Extensively studied
Niacin
Filling everyday nutrient gaps
Studied 20 mg to 500 mg a day
Well studied
Vitamin B6
Filling everyday nutrient gaps
Supporting role
Folate
12 studies
Methylation
Studied 400 mcg to 1 mg a day
Extensively studied
Vitamin B12
17 studies
Vitamin B12 status
Extensively studied
Biotin
Filling everyday nutrient gaps
Studied 30 mcg to 5 mg a day
Well studied
Pantothenic Acid
Filling everyday nutrient gaps
Studied 5 mg to 200 mg a day
Well studied
Choline
10 studies
Choline status
Studied 250 mg to 1 g a day
Extensively studied
Calcium
13 studies
Filling everyday nutrient gaps
Extensively studied
Phosphorus
Filling everyday nutrient gaps
Well studied
Iodine
13 studies
Iodine status
Studied 150 mcg to 500 mcg a day
Extensively studied
Magnesium
21 studies
Magnesium status
Studied 200 mg to 600 mg a day
Extensively studied
Zinc
22 studies
Filling everyday nutrient gaps
Studied 8 mg to 30 mg a day
Extensively studied
Selenium
15 studies
Filling everyday nutrient gaps
Studied 55 mcg to 200 mcg a day
Extensively studied
Copper
Filling everyday nutrient gaps
Studied 900 mcg to 2 mg a day
Well studied
Manganese
Filling everyday nutrient gaps
Well studied
Chromium
13 studies
Filling everyday nutrient gaps
Studied 25 mcg to 500 mcg a day
Well studied
Molybdenum
Filling everyday nutrient gaps
Studied 45 mcg to 200 mcg a day
Well studied
Sodium
11 studies
Hydration
Well studied
Potassium
16 studies
Filling everyday nutrient gaps
Extensively studied
Nutritive, Nutrient Dense Raw Superfood Complex
A 7732 mg blend of 35 ingredients, listed by weight.
Supporting role
Organic Alfalfa (aerial parts)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed first.
Supporting role
Organic Spirulina (whole plant)
17 studies
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed second.
Well studied
Organic Chlorella (cracked cell wall)
16 studies
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed third.
Well studied
Organic Wheat Grass (whole plant)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed fourth.
Supporting role
Organic Barley Grass (whole plant)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed fifth.
Supporting role
Organic Oat Grass (whole plant)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed sixth.
Supporting role
Organic Broccoli (whole plant)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed seventh.
Supporting role
Organic Spinach (whole plant)
Methylation. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed eighth.
Supporting role
Organic Kale (whole plant)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed ninth.
Supporting role
Organic Beet (root)
10 studies
Methylation. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed tenth.
Well studied
Organic Carrot (root)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 11th.
Supporting role
Organic Apple (fruit)
Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 12th.
Supporting role
Organic Blueberry (fruit)
11 studies
A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 13th.
Supporting role
Organic Raspberry (fruit)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 14th.
Supporting role
Organic Strawberry (fruit)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 15th.
Supporting role
Organic Acai (fruit)
A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 16th.
Supporting role
Organic Pomegranate (fruit)
14 studies
A balanced gut microbiome. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 17th.
Well studied
Organic Cranberry (fruit)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 18th.
Supporting role
Organic Goji Berry (fruit)
Iron status. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 19th.
Well studied
Organic Acerola Cherry (fruit)
Iron status. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 20th.
Supporting role
Organic Ginger (root)
20 studies
Regularity. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 21th.
Extensively studied
Organic Turmeric (root)
Part of this formula. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 22th.
Supporting role
Organic Milk Thistle (seed)
Everyday liver support. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 23th.
Well studied
Organic Dandelion (root)
Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 24th.
Supporting role
Organic Green Tea (leaf)
17 studies
Oxidative stress defence. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 25th.
Well studied
Organic Peppermint (leaf)
Comfort after a heavy meal. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 26th.
Supporting role
Organic Rosemary (leaf)
Feeding the bacteria that make butyrate. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 27th.
Well studied
Organic Sage (leaf)
Feeding the bacteria that make butyrate. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 28th.
Well studied
Organic Thyme (leaf)
Oxidative stress defence. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 29th.
Supporting role
Organic Cinnamon (bark)
20 studies
Breaking down what you eat. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 30th.
Well studied
Organic Licorice (root)
Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 31th.
Well studied
Organic Fennel (seed)
Comfort after a heavy meal. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 32th.
Supporting role
Organic Clove (bud)
Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 33th.
Supporting role
Organic Black Pepper (fruit)
Filling everyday nutrient gaps. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 34th.
Well studied
Organic Cayenne Pepper (fruit)
Digestive comfort. In the 7732 mg Nutritive, Nutrient Dense Raw Superfood Complex with 34 others, listed 35th.
Well studied
Nutrient Dense Herbs, Extracts & Antioxidants
A 2732 mg blend of 13 ingredients, listed by weight.
Supporting role
Moringa (leaf)
10 studies
Filling everyday nutrient gaps. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed first.
Well studied
Citrus Bioflavonoids (fruit)
Filling everyday nutrient gaps. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed second.
Well studied
Rhodiola (root) extract
Energy without a stimulant. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed third.
Extensively studied
Ashwagandha (root) extract
21 studies
Everyday stress. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed fourth.
Extensively studied
Ginseng (root) extract
15 studies
Energy without a stimulant. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed fifth.
Well studied
Green Coffee Bean (seed) extract
Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed sixth.
Well studied
Grape Seed (seed) extract
17 studies
Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed seventh.
Well studied
Alpha Lipoic Acid
16 studies
Glutathione status. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed eighth.
Well studied
Coenzyme Q10
20 studies
Cellular energy production. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed ninth.
Extensively studied
Resveratrol (root) extract
17 studies
Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed tenth.
Well studied
Lutein
15 studies
Eye health. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 11th.
Extensively studied
Zeaxanthin
17 studies
Eyes under bright screen light. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 12th.
Well studied
Lycopene
10 studies
Oxidative stress defence. In the 2732 mg Nutrient Dense Herbs, Extracts & Antioxidants with 12 others, listed 13th.
Well studied
Digestive Enzymes & Super Mushroom Complex
A 100 mg blend of eight ingredients, listed by weight.
Well studied
Amylase
Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed first.
Well studied
Protease
Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed second.
Supporting role
Lipase
Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed third.
Well studied
Cellulase
Filling everyday nutrient gaps. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed fourth.
Supporting role
Lactase
Breaking down what you eat. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed fifth.
Extensively studied
Reishi Mushroom (fruiting body) extract
A balanced gut microbiome. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed sixth.
Well studied
Shiitake Mushroom (fruiting body) extract
Vitamin D status. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed seventh.
Well studied
Maitake Mushroom (fruiting body) extract
Vitamin D status. In the 100 mg Digestive Enzymes & Super Mushroom Complex with seven others, listed eighth.
Well studied
Dairy Free Probiotic T20 CFU
A 50 mg blend of two ingredients, listed by weight.
Supporting role
Lactobacillus acidophilus (LA-02)
Comfort after dairy. In the 50 mg Dairy Free Probiotic T20 CFU with one other, listed first.
Well studied
Bifidobacterium lactis (BL-04)
Feeding the bacteria that make butyrate. In the 50 mg Dairy Free Probiotic T20 CFU with one other, listed second.
Well studied
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

51 more
Pantothenic Acid

Randomised trial, 2014

Pantethine, a vitamin B5 derivative, lowered LDL cholesterol by about 11 percent from baseline versus placebo over 16 weeks in adults at low to moderate cardiovascular risk.

Vascular Health and Risk Management
Organic Spirulina (whole plant)

Meta-analysis, 2024

Across pooled trials, daily spirulina lowered blood pressure in adults, cutting the top number by about 4.4 and the bottom number by about 2.8.

Phytotherapy Research
Organic Chlorella (cracked cell wall)

Meta-analysis of randomized controlled trials, 2017

Across 19 trials in 797 people, chlorella lowered the top blood pressure number by about 4.5 points and the bottom by about 1.6 points.

Clinical Nutrition
Organic Spinach (whole plant)

Meta-analysis, 2025

Pooling five trials, spinach-derived thylakoid supplements lowered reported hunger by 2.415 mm on a rating scale and raised fullness after eating, with the effect scaling with dose.

Nutrition reviews
Organic Wheat Grass (whole plant)

Narrative review, 2025

Reviewing the human literature, the authors find mostly small early studies, with the steadiest signals on oxidative-stress markers and hemoglobin, and call for more rigorous trials.

Journal of Pharmacy and Bioallied Sciences
Organic Barley Grass (whole plant)

Randomised trial, 2020

In 18 young adults, a barley leaf drink with an afternoon snack lowered the blood sugar rise afterward and at dinner, most when dinner sugar ran high.

Nutrients
Organic Raspberry (fruit)

Randomised trial, 2025

In healthy adults, polyphenols from raspberry leaf tea lowered the post-meal glucose and insulin rise compared with control.

Nutrients
Biotin

Meta-analysis, 2025

In a network meta-analysis of 19 trials with 1,658 participants, biotin-containing preparations were among the supplements linked to greater hair density, though most individual trials were small.

Frontiers in nutrition
Magnesium

Meta-analysis, 2016

Pooling 34 trials, magnesium lowered the top blood pressure number by about 2 mmHg.

The paper
Zhang et al., 2016PMID 27402922
Organic Green Tea (leaf)

Meta-analysis, 2014

Across 13 trials, green tea catechins lowered systolic blood pressure by about 2.08 mmHg and diastolic by about 1.71 mmHg compared with control.

European Journal of Nutrition
Folate

About 23 percent lower plasma homocysteine at 0.8 mg daily, with 0.2 mg and 0.4 mg reaching roughly 60 and 90 percent of that

Lowers homocysteine, a blood marker tied to heart risk. Measured in adults, standardised to a pretreatment homocysteine of 12 micromol per litre (95% CI 21 to 26 percent).

Meta-analysis
Organic Alfalfa (aerial parts)

Clinical trial, 1987

Fifteen adults with elevated blood lipids who ate 40 g of heat-treated alfalfa seeds three times daily for eight weeks saw median total cholesterol fall about 17% and LDL cholesterol about 18%, with values returning to starting levels after they stopped.

The paper
Organic Goji Berry (fruit)

Meta-analysis, 2023

Pooling human trials, Lycium barbarum supplementation was associated with modest reductions in total cholesterol and triglycerides in adults, with variation across studies.

Medicine
Organic Acai (fruit)

Meta-analysis, 2023

Pooling randomised trials of anthocyanins, the pigment class that acai is rich in, found modest reductions in total and LDL cholesterol.

Frontiers in nutrition
Sodium

Systematic review, 2026

A systematic review catalogued gastrointestinal symptoms reported across sodium bicarbonate dosing protocols and described how symptom burden varies with dose, timing and whether the dose is split or given with food.

European Journal of Sport Science
Organic Carrot (root)

Systematic review, 2024

Across the reviewed human studies, higher dietary carotenoid intake tracked with more favourable cardiovascular risk markers, an association rather than a demonstrated cause.

Nutrients
Organic Broccoli (whole plant)

Randomised trial, 2025

Broccoli supplementation combined with exercise was tested against exercise alone on metabolic and lipoprotein blood markers in adults.

Nutrients
Organic Strawberry (fruit)

Meta-analysis, 2019

Across combined trials, strawberries improved several heart-related blood markers in adults, including lower LDL cholesterol and a blood marker of inflammation.

Food & function
Organic Sage (leaf)

Randomised trial, 2016

In resistance-trained adults, a multi-ingredient supplement containing banaba leaf extract raised resting metabolic rate acutely, with hemodynamic measures reported as unchanged and the blend meaning the effect is not attributable to banaba alone.

Journal of the International Society of Sports Nutrition
Organic Acerola Cherry (fruit)

Randomised trial, 2011

Encapsulated fruit and vegetable concentrates containing acerola were tested for effects on blood vessel dilation in adults with several metabolic risk markers.

Nutrition journal
Molybdenum

Metabolic balance study (crossover), 2006

In 43 healthy young women eating normal diets, over 90 percent of dietary molybdenum was absorbed and mostly excreted in urine, staying balanced across intakes of about 150 to 318 micrograms a day.

Journal of Trace Elements in Medicine and Biology
Organic Apple (fruit)

Systematic review, 2025

Pooling human trials of apple cider vinegar, the review found small reductions in body weight and waist measures in adults with raised blood sugar or excess body weight, and described the evidence base as limited.

Nutrients
Organic Sage (leaf)

Systematic review, 2024

A systematic review of nutraceuticals in adults with elevated blood sugar lists banaba leaf and its corosolic acid among the plant extracts with reported effects on glucose handling, at modest evidence quality.

Nutrients
Organic Kale (whole plant)

Randomised trial, 2024

A daily freeze-dried kale bar improved several blood sugar and metabolic markers in adults with high blood sugar compared with placebo.

Nutrients
Vitamin K

Meta-analysis, 2022

Pooling 16 randomized trials in 6,425 postmenopausal women, vitamin K2 supplementation improved lumbar spine bone mineral density and lowered undercarboxylated osteocalcin.

Frontiers in Public Health
Selenium

Meta-analysis, 2018

Pooling trials, selenium raised the share of motile sperm by about 3.3 percentage points, with a smaller rise in normally shaped sperm and a higher sperm concentration.

Advances in Nutrition
Organic Beet (root)

Meta-analysis, 2024

Pooled trials found dietary nitrate supplementation improved high intensity cycling sprint performance in recreationally active people by a small margin.

Nutrients
Organic Blueberry (fruit)

Meta-analysis, 2025

Across trials, blueberries produced small improvements in memory and executive function measures.

Biogerontology
Organic Thyme (leaf)

Meta-analysis, 2025

Pooled trials of Zataria multiflora, a thyme-family plant rather than thyme itself, reported higher lung function measures and lower oxidative stress markers in adults.

BMC complementary medicine and therapies
Organic Dandelion (root)

Clinical trial, 2009

In a pilot study of 17 volunteers, a fresh dandelion leaf extract increased urination frequency in the 5 hours after the first dose and raised the urine output to fluid intake ratio after the second dose, with no change after the third.

Journal of Alternative and Complementary Medicine
Riboflavin

Meta-analysis, 2024

In a dose-response meta-analysis of randomised trials, riboflavin was associated with about 1.3 fewer severe recurring headache attacks per month compared with control.

Neurological Sciences
Organic Ginger (root)

Meta-analysis, 2020

Ginger eased nausea severity during pregnancy versus placebo (standardized mean difference 0.82), pooling 13 trials in 1,174 women, with no clear effect on vomiting.

J Matern Fetal Neonatal Med
Thiamin

Randomised trial, 2026

Thiamin supplementation improved the thiamin pyrophosphate effect, a blood marker of thiamin adequacy, in children whose levels were low.

Scientific reports
Choline

Meta-analysis, 2025

In children of pregnancies with heavy alcohol exposure, choline in pregnancy was linked to higher memory scores (moderate confidence), and after birth to better overall thinking (lower confidence).

Pediatrics and Neonatology
Iodine

Systematic review and meta-analysis, 2020

In pregnant women with mild to moderate iodine deficiency, iodine lowered a thyroid marker and curbed the usual pregnancy rise in thyroid size. Infant cognitive, language and motor scores showed no change across trials.

American Journal of Clinical Nutrition
Copper

Systematic review and meta-analysis of observational studies, 2025

Pooling observational studies, higher dietary copper intake was associated with slightly higher lumbar spine bone mineral density (mean difference 0.02 g/cm2), while the hip difference was not statistically significant.

Calcified Tissue International

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people22 human studies on Zinc back this formula, each one cited.
  • A mechanism that is settledHow Vitamin A and Vitamin C work is settled pharmacology.
  • Studied together, not just separatelyVitamin A and Vitamin E have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Serving amount inside the studied rangeEach serving carries 400 mg of Vitamin C, inside the range the published research used.
  • A stated daily maintenance amountVitamin C is here at a daily maintenance amount, which is what a daily supplement is for.
  • Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
  • The exact form, describedThe label names its forms exactly: Retinyl palmitate, Ascorbic acid, Vitamin D3 in a carrier oil, lanolin-derived. The record says what each one is and what it suits.
  • An absorption partner in the same servingLipase is in the same serving as Vitamin D3, where it has a measured absorption role.
  • A declared blend totalNutritive, Nutrient Dense Raw Superfood Complex declares its total, 7,732 mg per serving, with 35 ingredients listed by weight.
  • Where it comes from and how it is madeVitamin A is made by more than one route.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
Studied together

The combinations the trials actually measured.

Five pairings in this formula have been studied as combinations in human trials. Each finding below is what a named study measured, cited and dated, never written by the brand.

  • Lutein + ZeaxanthinVision

    In the AREDS2 trial long-term follow-up, lutein and zeaxanthin taken together were associated with a modestly lower risk of progression to late age-related macular degeneration, while the trial original primary analysis was not significant.

    Promising
  • Zinc + SeleniumImmune

    In a two-year trial in older adults, zinc taken together with selenium improved the antibody response to influenza vaccination.

    Early
  • Calcium + MagnesiumStrength

    In a 12-month randomised, double-blind trial, 98 adults aged 50 and over drank a litre a day of either a naturally calcium- and magnesium-rich mineral water or a low-mineral water. The mineral-rich group had fewer falls at the 6-month assessment and higher appendicular muscle mass, with the minerals delivered as drinking water rather than a capsule.

    Promising
  • Folate + Vitamin B12 + Vitamin B6Heart

    In a 2025 network meta-analysis of 16 randomized trials in healthy adults, folic acid taken together with vitamins B6 and B12 lowered blood homocysteine more than any single supplement, with the 1 mg folic acid plus 7.2 mg B6 plus 20 micrograms B12 arm ranked most effective versus placebo (mean difference -1.03 micromol/L, 95% CI -1.71 to -0.36).

    Promising
  • Magnesium + Vitamin B6Calm

    In an 8-week randomized trial of 264 stressed healthy adults with low magnesium, magnesium plus vitamin B6 and magnesium alone reduced perceived stress about equally overall. In the prespecified subgroup that started with severe stress, the combination improved stress scores 24% more than magnesium alone.

    Early

Research strength. Research strength says how much work stands behind the combination. It is never a product score.

Fail closed. Where actives were studied on their own rather than together, each shows on its own evidence, never a combined effect no trial measured.

Independent record. Every finding is cited to a named trial, dated, and never written by the brand.

Findings from trials that studied these actives as a combination. Context for how the actives were tested together, not a statement about any individual and not a claim about this product.

How much it moves the numbers

The size of the effect, in plain numbers.

Where a trial measured an actual number, we show it next to the claim. It is the average across the trials, never a promise about one person.

Vitamin Crisk of developing a cold
Average change in the trials

About 52 percent lower risk of developing a cold, in trials of people undergoing brief periods of severe physical exertion.

Measured in
marathon runners, skiers and soldiers on subarctic exercises
Confidence interval
risk ratio 0.48, 95% CI 0.35 to 0.64

Read at the source. The magnitude sits beside the same trial the claim already cites. It describes what the trials measured, never what any one person will feel.

What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Vitamin Cwithin 24 hours of a single doseMeasured within a day

    In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

    Strong
  • Vitamin D3about 3 months of daily useBuilds with daily use

    In the trial record, blood vitamin D rises for about 3 months of daily vitamin D3 and then holds at a plateau, near 69 nmol/L at 1,000 IU a day, from a starting level near 41 nmol/L.

    Early
  • Vitamin Eabsorbed slowly, tracked over 72 hoursMeasured within a day

    In a 3-phase crossover using two deuterium-labelled forms of alpha-tocopherol, healthy women absorbed about 55 percent of an oral dose taken with a 40 percent fat meal and about 64 percent with a fat-free meal, with samples tracked over 72 hours. The authors conclude absorption is not limited by absent fat or fasting, and that vitamin E leaves the intestine by a prolonged process.

    Promising
  • Vitamin Kabout four weeks of daily useBuilds with daily use

    A double-blind randomised dose-finding trial gave 60 postmenopausal women aged 50 to 69 either 0, 50, 100 or 200 micrograms of menaquinone-7 daily for four weeks on a controlled diet. The ratio of carboxylated to undercarboxylated osteocalcin rose dose dependently, with significant differences from the 0 microgram group at 100 and 200 micrograms. A companion 12-week trial in 120 people aged 20 to 69 confirmed the change at 100 micrograms daily. Both studies were run by authors affiliated with the R and D division of J-Oil Mills. An independent 8-week double-blind trial in 55 healthy prepubertal children found the same direction at 45 micrograms daily. What was measured is a blood marker of vitamin K status, not bone density and not a sensation.

    Promising
  • Vitamin Kthree years of daily use, with measurements at one, two and three yearsBuilds with daily use

    A double-blind randomised trial gave 244 healthy postmenopausal women either placebo or 180 micrograms of menaquinone-7 daily for three years, with bone mineral density measured by DXA at baseline and after each year. Menaquinone-7 decreased the age-related decline in bone mineral content and bone mineral density at the lumbar spine and femoral neck, but not at the total hip. The effect is a slowed decline rather than a gain, and the trial ran three years rather than weeks.

    Promising
  • Thiaminabout 18 to 30 days of restricted intakeBuilds with daily use

    In the controlled depletion study the EFSA reference opinion reviews, restricting thiamin intake to 0.009 to 0.015 mg/MJ for 30 days brought urinary free thiamin excretion from a mean of 0.283 mg/24 h down to undetectable levels by day 18 of the depletion period.

    Promising
17 more
  • Thiaminabout 1 week of renewed intakeBuilds with daily use

    In the same depletion and repletion record the EFSA reference opinion reviews, erythrocyte transketolase activity fell progressively to about 75% of baseline during the 30-day depletion period and returned to its baseline value after 1 week of thiamin repletion.

    Promising
  • Riboflavinabout 8 weeks of daily intakeBuilds with daily use

    In an intervention the EFSA reference opinion reviews, adults whose baseline riboflavin intake and status were unknown received 5 mg/day of riboflavin for 8 weeks, and haemoglobin concentration, haematocrit and erythrocyte count all rose significantly over that period.

    Early
  • Vitamin B6about 20 to 40 days to clear after stoppingBuilds with daily use

    An expert consensus on vitamin B6 use, developed by a six-member Delphi panel with a structured evidence-quality assessment, calculated from pharmacokinetic parameters that complete clearance of vitamin B6 from the body takes a washout period of about 20 to 40 days after intake stops.

    Early
  • Folatea median of about 36 weeks of daily intakeBuilds with daily use

    A systematic review and Bayesian meta-analysis drew on 108 articles from 14,002 screened records and modelled blood folate against folic acid intake using one-compartment pharmacokinetic models. Red blood cell folate rose 1.78 fold from baseline to steady state at 375 to 570 ug folic acid per day, and reaching that steady state took a median of 36 weeks, 95% credible interval 27 to 52 weeks. Serum or plasma folate rose 11.6% for every 100 ug per day of folic acid intake, 95% credible interval 8.4 to 14.9.

    Strong
  • Folateabout 18 days for serum folate to reach its maximumBuilds with daily use

    A kinetic study in six healthy men aged 22 to 31 gave 3.6 umol per day, 1.6 mg, of deuterium-labelled folic acid for four weeks, with folate tracked in serum, erythrocytes and urine by microbiological assay and gas chromatography mass spectrometry. Serum folate reached its maximum concentration in about 18 days, while isotopic labelling of erythrocyte folate kept rising across the whole four weeks. After supplementation stopped, red blood cell folate and urinary folate excretion declined linearly, and serum folate fell with a slow-phase half-life of 18.7 days. One study, six men, no control group.

    Early
  • Vitamin B12about 16 weeks of daily oral useBuilds with daily use

    A randomised, double-blind, parallel-group dose-finding trial in 120 older people with mild vitamin B12 deficiency, defined as serum B12 of 100 to 300 pmol/L with methylmalonic acid at or above 0.26 umol/L, gave daily oral cyanocobalamin at 2.5, 100, 250, 500 or 1000 ug for 16 weeks. Mean plasma methylmalonic acid fell 16%, 16%, 23%, 33% and 33% across those doses. Daily doses of 647 to 1032 ug accounted for 80% to 90% of the estimated maximum reduction. The window was measured on a blood marker of B12 status, not on a symptom.

    Promising
  • Vitamin B12serum levels peak about seven hours after a single tabletMeasured within a day

    An open-label randomised single-dose pharmacokinetic study in 20 healthy men aged 20 to 45, conducted and authored by staff of Emisphere Technologies, the developer of the SNAC carrier under test, measured serum vitamin B12 after one 5 mg cyanocobalamin tablet, with six men on the marketed tablet. Time to peak serum B12 was 6.83 hours for the marketed tablet and 0.5 hours for the carrier coformulation. Absolute bioavailability was 2.16% and 5.09% respectively. One trial, six men per arm. Serum concentration was measured, not any symptom.

    Early
  • Biotinabout 5 to 6 months of daily useBuilds with daily use

    In an open trial with no placebo arm, 71 patients with brittle or splitting fingernails took 2.5 mg of biotin a day. Of the 45 cases that could be evaluated, 41 were rated as having firmer and harder nails after an average of 5.5 months of treatment, standard deviation 2.3 months. The rating was clinical judgement rather than an instrument reading, and there was no control group, so the window describes when the raters recorded change, not a placebo adjusted effect.

    Early
  • Cholineabout 10 to 12 weeks of daily intakeBuilds with daily use

    In a controlled feeding study, lactating women randomised to 480 or 930 mg choline per day for 10 to 12 weeks showed that the higher intake increased breast milk choline content by raising output of endogenously synthesised choline metabolites.

    Promising
  • Calciumwithin about one to six hours of a single doseMeasured within a day

    A randomised cross-over trial in ten women of mean age 69 gave a single 500 mg dose of calcium as citrate fasting, citrate with a meal, fortified juice or a dairy product meal, with blood drawn before and at 1, 2, 4 and 6 hours. Serum ionised and total calcium increased significantly from baseline over six hours, with the rise similar after fortified juice, delayed when citrate was taken with a meal and smaller after the dairy meal. A separate double-blind cross-over trial in 25 postmenopausal women measured parathyroid hormone and a bone resorption marker 12 hours after a single calcium dose. Ten participants is a small sample, and what moved was blood chemistry, not a sensation.

    Promising
  • Phosphorusthe hours after a mealMeasured within a day

    A systematic review of ten randomised crossover trials in 225 healthy adults aged 18 to 64 examined inorganic phosphorus supplementation taken with meals against postprandial metabolic outcomes. Three of the four studies measuring diet-induced thermogenesis reported a significant positive association with phosphorus in the hours after eating. The reviewers temper the finding: few studies, modest samples, methodological heterogeneity, and association rather than established cause.

    Early
  • Iodinefrom about eight weeks, deepening through twenty-four weeksBuilds with daily use

    In a 24 week randomised double-blind placebo-controlled trial in 112 mildly iodine-deficient New Zealand adults aged 18 to 40, 150 micrograms of iodine a day as potassium iodate lowered thyroglobulin, a blood marker of iodine status, by 12 percent at 8 weeks, 20 percent at 16 weeks and 27 percent at 24 weeks compared with placebo. Median urinary iodine reached 168 micrograms per litre against 79 on placebo. TSH and free T4 stayed within normal range and did not change significantly.

    Promising
  • Zincover about five days of lozenges started within 24 hours of symptom onsetBuilds with daily use

    Across three randomised placebo-controlled trials pooled as individual patient data (199 adults with naturally acquired colds, 80 to 92 mg of elemental zinc a day as acetate lozenges), 70 percent of the zinc group had recovered by day 5 against 27 percent on placebo, and colds ran 2.73 days shorter against a 7 day average duration. A separate meta-analysis of seven lozenge trials (575 participants, doses above 75 mg a day, zinc acetate or zinc gluconate) measured cold duration 33 percent shorter, with no significant difference between the two salts.

    Strong
  • Zincabout two to four weeks of daily intakeBuilds with daily use

    In a controlled feeding study in nine healthy men, six weeks of restricted zinc intake raised DNA strand breaks in peripheral blood cells, and four weeks of repletion at 11 mg a day, with 20 mg of supplemental zinc for the first seven days, reversed the rise. In a separate randomised placebo-controlled trial in 40 Ethiopian women eating a high-phytate diet, 20 mg a day of zinc sulfate for 17 days lowered mean comet tail moment from 39.7 to 30.0 while plasma zinc did not change significantly. Both windows were measured on a DNA damage marker in blood cells, not on a symptom.

    Early
  • Seleniumabout ten weeks of daily useBuilds with daily use

    In a 12 week randomised double-blind placebo-controlled trial in 119 healthy UK adults aged 50 to 64, mean plasma selenium rose from 95.7 ng/mL at baseline to steady state by week 10, reaching 118.3, 152.0 and 177.4 ng/mL on 50, 100 and 200 micrograms a day of selenium-enriched yeast. Plasma selenoprotein P rose in every selenium arm. Platelet glutathione peroxidase activity did not change significantly at any dose or form.

    Promising
  • Copperabout four to eight weeks of daily useBuilds with daily use

    In an 8 week pilot with a parallel placebo group, 8 young women taking 2 mg of copper a day as copper glycinate showed a 9 percent mean rise in serum ceruloplasmin and a 75 percent rise in diamine oxidase, alongside a 39 percent fall in plasma F2-alpha isoprostanes. Erythrocyte copper-zinc superoxide dismutase did not change. In a separate 4 week double-blind crossover in 20 men with moderately high cholesterol at the same 2 mg a day, copper moved no measure across the whole group and raised superoxide dismutase and diamine oxidase only in the 10 men who started below the median. Both are small and both measured enzymes in blood, not a symptom.

    Early
  • Sodiumabout 3 days to 4 weeks of steady intakeBuilds with daily use

    In the excretion studies the EFSA reference opinion reviews, urinary output closely tracked dietary sodium once intake was held steady: 98% of dietary sodium appeared in 24-hour urine in a 3-day study, and 86% of sodium ingested over 4 weeks was recovered in 24-hour urine collected during the same period.

    Early

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

12 ingredients, from each one's own page.

  • Vitamin AWeeks, not days

    Weeks to months. Liver stores buffer intake, so vitamin A status moves slowly and shows up on a blood panel rather than as a sensation.

    Its own page, the plain answer on timing

  • Vitamin CWithin hours

    Blood levels rise within hours and tissue pools fill over days. Collagen-linked changes in skin and gums build over weeks and show as tissue quality, not as a sensation.

    Its own page, the plain answer on timing

  • Vitamin D3About six to twelve weeks

    25-hydroxyvitamin D climbs over roughly six to twelve weeks of daily dosing before it plateaus. It's a blood level you watch rather than a feeling.

    Its own page, the plain answer on timing

  • Vitamin EWeeks, not days

    Plasma alpha-tocopherol climbs within days of daily intake, and anything you'd notice in skin condition is a slow change across a couple of months.

    Its own page, the plain answer on timing

  • Vitamin KWithin days

    Clotting factor carboxylation responds within days. The bone marker undercarboxylated osteocalcin shifts across roughly four to twelve weeks, so this shows up on a panel.

    Its own page, the plain answer on timing

  • Thiamin

    There is no onset to time in the usual sense. Status markers such as erythrocyte transketolase activity move across weeks, and that is where the change is read.

    Its own page, the plain answer on timing

6 more

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • Cholecalciferol (vitamin D3)

    The animal-sourced form of vitamin D, made in skin under UVB light and produced commercially from lanolin. Fat-soluble, so it travels with dietary fat and is stored in body fat.

    Fits
    Raising and holding vitamin D status, and the form most supplement trials use.
    Trade-off
    Being fat-soluble it accumulates with sustained high dosing, so intakes are set against the tolerable upper level rather than topped up freely.

    In a 12-week double-blind randomised controlled trial in 108 young women in urban Bangalore, most of whom began vitamin D-deficient, daily vitamin D3 at 400, 600 or 800 IU in a fortified wafer raised serum 25-hydroxyvitamin D, parathyroid hormone fell over time, and effects on bone-turnover markers were modest and not dose specific. The 800 IU dose brought 65 percent of participants to sufficiency.

  • Riboflavin

    The free vitamin B2 molecule, an isoalloxazine ring joined to a ribitol sugar chain, supplied as the unmodified crystalline compound with no added salt or phosphate group.

    Fits
    It is the form most panels list simply as riboflavin or vitamin B2.
    Trade-off
    It is intensely yellow and only sparingly water soluble, so it can tint a finished product and tends to resist dissolving cleanly in a liquid or a fast-melt format.
  • Nicotinic acid

    The free-acid form of vitamin B3, pyridine-3-carboxylic acid. It is the reference form of niacin, a small water-soluble molecule carrying a bare carboxylic acid group on the pyridine ring.

    Fits
    The long-standing reference form for meeting a vitamin B3 requirement.
    Trade-off
    This is the form behind the familiar warm, tingling skin flush that many people notice soon after a larger dose, a recognized property of the free acid that leads some formulators to reach for an amide or ester instead.
  • D-pantothenic acid

    The free acid form of vitamin B5, an amide of pantoic acid and beta-alanine, supplied as a viscous hygroscopic oil or a stabilised liquid rather than a dry salt.

    Fits
    The un-neutralised acid carries no mineral counterion, so it suits liquid drops, syrups and formats where a calcium or sodium salt is not wanted.
    Trade-off
    It is hygroscopic and tends to draw water and turn sticky, which makes it awkward to hold as a dry powder without added stabilisers.
  • Licorice rootActive and formulation aid

    Unfractionated root material carrying the full constituent profile including undeclared glycyrrhizin

    Fits
    Traditional teas, decoctions and classical multi-herb formulas where the root also serves as sweetener and flavour modifier
    Trade-off
    Glycyrrhizin content is not declared and varies with species, root age and origin, so intake cannot be quantified from the label
  • Standardised root extract

    An extract of the root alone, standardised to its withanolide content, the constituent family the clinical literature doses by. Root-only sourcing distinguishes it from root-plus-leaf extracts.

    Fits
    Formulas that want the dosing and safety record of the studied preparations, since most trials used standardised root-only extracts at 125 to 600 mg a day.
    Trade-off
    Standardisation states withanolide content, not which withanolides. Extracts differ in their glycoside profile even at the same declared percentage.

    A systematic review of 23 randomised trials in 2,317 generally healthy adults taking standardised ashwagandha root extract at 125 to 600 mg per day, from a single dose to 180 days, found hepatic, renal, haematological, endocrine and cardiovascular biomarkers stayed within normal clinical ranges, reductions in cortisol were consistently observed, testosterone shifts stayed within physiological range, and no serious adverse events were attributed to the extract.

  • 4 more
  • Alpha-lipoic acid (racemic)

    A 50:50 mixture of the R and S enantiomers of lipoic acid, sold as the free acid. The same molecule is also labelled thioctic acid.

    Fits
    A low-cost form to produce and the one used across most of the older clinical literature, which makes it a straightforward default for a general-purpose formula.
    Trade-off
    Half of the labelled material is the S enantiomer, which does not occur naturally, and as a free acid it can polymerise when exposed to heat or stomach acid.

    In an open-label four-way crossover in 24 adults, a racemic solution produced higher peak plasma concentrations of both enantiomers than the 200, 300, and 600 mg tablet forms.

  • Ubiquinone

    The oxidised, quinone form of coenzyme Q10: a fat soluble benzoquinone ring carrying a ten unit isoprenoid tail, supplied as a yellow orange crystalline powder made by yeast fermentation. It is the redox form nearly all CoQ10 raw material ships as, and the form used across the long running clinical trial record.

    Fits
    Formulas built on that historical trial record, including the cardiovascular outcome trials, which used the oxidised form. As a stable crystalline material it handles well in a factory without the oxygen excluding packing a reduced form asks for, and it goes into softgels, tablets, hard capsules and dry blends alike.
    Trade-off
    Oral absorption of CoQ10 in any redox form is low and depends heavily on the lipid matrix around it. The head to head crossovers against ubiquinol are small, short and single dose, so they settle little on their own.
  • Trans-resveratrol

    The free stilbene aglycone in its trans geometric configuration, a single molecule of formula C14H12O3 (three hydroxyls on a two-ring stilbene skeleton), sold either purified from plant material or made synthetically.

    Fits
    It is the geometric isomer characterised across the resveratrol literature and the one most panels standardise to, and it holds its structure in dry capsules and tablets when kept from light and heat.
    Trade-off
    The trans double bond isomerises toward the cis form under ultraviolet light, and the free aglycone has low water solubility, so it depends on light-protected packaging to keep its declared isomer.
  • Ethyl ester (EE)

    During concentration, EPA and DHA are cleaved from glycerol and each bound individually to ethanol, so every fatty acid rides on its own ethyl group rather than a shared glycerol backbone. This arrangement allows a high EPA and DHA percentage.

    Fits
    Suits high-concentration products where a large EPA and DHA figure per capsule is the goal and the manufacturer stops at the ester stage rather than re-esterifying.
    Trade-off
    Each fatty acid is bound to ethanol rather than a shared glycerol backbone, a more processed arrangement than either triglyceride form, and one that does not blend into a food-oil matrix as readily.

    In a six-month double-blind RCT in 150 adults, the rise in the omega-3 index (EPA and DHA in red blood cell membranes) with the ethyl ester form was smaller than with an equal dose of re-esterified triglyceride. A two-week trial found lower serum appearance versus natural fish oil.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.

Best forGram-scale actives: creatine, collagen, protein, electrolytes, beta-alanine.

Questions shoppers ask

Is AG1 Athletic Greens independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in AG1 Athletic Greens?
AG1 Athletic Greens is built on Vitamin A, Vitamin C, Vitamin D3, Vitamin E, Vitamin K, Thiamin, and more. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 8,931 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

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