Skip to main content
Verified by IngredientMD/Nested Naturals/Super Greens
VERIFIED BYingredientMD

Super Greens.

Stronger in a pairNested Naturals, verified Oct 2026Formula verified. Independently reviewed.Independent review. Not commissioned by Nested Naturals.

Dulse Powder is the lead active here, studied most for iodine status. In the 3847mg Alkalizing Blend with nine others, listed sixth. Magnesium is the most studied active here, with 21 human studies behind it, each one cited. Who it fits: for everyone, adults.

Clinically dosedFull label disclosure
56Active ingredientsWell studiedResearch base387Human studies
Super GreensVerified by IngredientMD
Nested NaturalsIngredientMD
The verdict
Stronger in a pair
For everyone, adults.
How we verify

The brand submits the formula. We read the supplement facts panel and weigh dose, form and synergy against the clinical evidence. Labs test. IngredientMD verifies. The fee pays for review time, never for the outcome.

The formula
Calcium: Filling everyday nutrient gapsExtensively studied
Iron: Iron statusExtensively studied
Potassium: Filling everyday nutrient gapsExtensively studied
Vitamin A: Filling everyday nutrient gapsExtensively studied
Vitamin C: Iron statusExtensively studied
Vitamin K: Filling everyday nutrient gapsExtensively studied
Thiamine: Filling everyday nutrient gapsExtensively studied
Riboflavin: Filling everyday nutrient gapsExtensively studied
Vitamin B6: Filling everyday nutrient gapsSupporting role
Folate: MethylationExtensively studied
Vitamin B12: Vitamin B12 statusExtensively studied
Biotin: Filling everyday nutrient gapsWell studied
Phosphorus: Filling everyday nutrient gapsWell studied
Iodine: Iodine statusExtensively studied
Magnesium: Magnesium statusExtensively studied
Selenium: Filling everyday nutrient gapsExtensively studied
Copper: Filling everyday nutrient gapsWell studied
Manganese: Filling everyday nutrient gapsWell studied
Fiber Blend: A 2700mg blend of three ingredients, listed by weight.Supporting role
Apple Powder: Digestive comfort. In the 2700mg Fiber Blend with two others, listed first.Supporting role
Rice Bran Solubles Powder: Filling everyday nutrient gaps. In the 2700mg Fiber Blend with two others, listed second.Supporting role
Jerusalem Artichoke Inulin Powder: Filling everyday nutrient gaps. In the 2700mg Fiber Blend with two others, listed third.Well studied
Antioxidant/Immune Blend: A 1053mg blend of 12 ingredients, listed by weight.Supporting role
Beetroot Powder: Oxygen delivery to working muscle. In the 1053mg Antioxidant/Immune Blend with 11 others, listed first.Well studied
Acerola Extract: Iron status. In the 1053mg Antioxidant/Immune Blend with 11 others, listed second.Supporting role
Eleuthero Root Powder: Energy without a stimulant. In the 1053mg Antioxidant/Immune Blend with 11 others, listed third.Well studied
Echinacea Powder: The immune barrier in the nose and throat. In the 1053mg Antioxidant/Immune Blend with 11 others, listed fourth.Well studied
Acai Juice Powder: A balanced gut microbiome. In the 1053mg Antioxidant/Immune Blend with 11 others, listed fifth.Supporting role
Green Tea Extract Powder: A healthy inflammatory response. In the 1053mg Antioxidant/Immune Blend with 11 others, listed sixth.Well studied
Milk Thistle Powder: Everyday liver support. In the 1053mg Antioxidant/Immune Blend with 11 others, listed seventh.Well studied
Ginkgo Leaf Extract Powder: Blood flow. In the 1053mg Antioxidant/Immune Blend with 11 others, listed eighth.Well studied
Luo Han Guo Extract Powder: Healthy glucose metabolism. In the 1053mg Antioxidant/Immune Blend with 11 others, listed ninth.Supporting role
Raspberry Powder: Filling everyday nutrient gaps. In the 1053mg Antioxidant/Immune Blend with 11 others, listed tenth.Supporting role
Blueberry Powder: A balanced gut microbiome. In the 1053mg Antioxidant/Immune Blend with 11 others, listed 11th.Supporting role
Carrot Powder: Filling everyday nutrient gaps. In the 1053mg Antioxidant/Immune Blend with 11 others, listed 12th.Supporting role
Alkalizing Blend: A 3847mg blend of ten ingredients, listed by weight.Supporting role
Barley Grass (Whole Leaf) Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed first.Supporting role
Alfalfa Grass (Whole Leaf) Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed second.Supporting role
Wheatgrass (Whole Leaf) Powder: Feeding the bacteria that make butyrate. In the 3847mg Alkalizing Blend with nine others, listed third.Well studied
Spirulina Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed fourth.Well studied
Chlorella (Cracked Cell) Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed fifth.Well studied
Dulse Powder: Iodine status. In the 3847mg Alkalizing Blend with nine others, listed sixth.Key driver
Spinach Powder: Methylation. In the 3847mg Alkalizing Blend with nine others, listed seventh.Supporting role
Broccoli Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed eighth.Supporting role
Parsley Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed ninth.Supporting role
Collard Green Powder: Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed tenth.Supporting role
Probiotic Blend: A 333mg blend of three ingredients, listed by weight.Supporting role
Lactobacillus gasseri: A balanced gut microbiome. In the 333mg Probiotic Blend with two others, listed first.Well studied
Bifidobacterium bifidum: A balanced gut microbiome. In the 333mg Probiotic Blend with two others, listed second.Supporting role
Bifidobacterium longum: Gut barrier integrity. In the 333mg Probiotic Blend with two others, listed third.Well studied
DigeZyme (Enzyme Blend): A 67mg blend of five ingredients, listed by weight.Supporting role
Amylase: Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed first.Well studied
Protease: Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed second.Supporting role
Lactase: Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed third.Extensively studied
Lipase: Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed fourth.Well studied
Cellulase: Filling everyday nutrient gaps. In the 67mg DigeZyme (Enzyme Blend) with four others, listed fifth.Supporting role

How we read this product

Source: Supplement facts
Supplement Facts panel for Super Greens
  1. 01
    We read the label.

    The panel on the left is the one we evaluated, line by line.

  2. 02
    Every active, separately.

    All 56 actives checked against the clinical evidence: dose, form, and what the research actually shows.

  3. 03
    Then the formula as a whole.

    Doses, ratios, and how the ingredients work together. That assessment is the verdict above: "Stronger in a pair".

  4. 04
    Earned, not bought.

    The verdict is public and identical whether or not a brand pays. A formula that does not clear the bar gets nothing.

Read by the engine against 2.1 million data points from clinical trials, PubMed and more than a hundred vetted sources. No individual reviewer is named or implied.

The receipts

Well studied
Research base
387
Human studies
19 mg
Calcium
2 mg
Iron

Inside the formula

Calcium
13 studies
Filling everyday nutrient gaps
Extensively studied
Iron
17 studies
Iron status
Extensively studied
Potassium
16 studies
Filling everyday nutrient gaps
Extensively studied
Vitamin A
Filling everyday nutrient gaps
Extensively studied
Vitamin C
20 studies
Iron status
Extensively studied
Vitamin K
11 studies
Filling everyday nutrient gaps
Extensively studied
Thiamine
14 studies
Filling everyday nutrient gaps
Extensively studied
Riboflavin
10 studies
Filling everyday nutrient gaps
Extensively studied
Vitamin B6
Filling everyday nutrient gaps
Supporting role
Folate
12 studies
Methylation
Extensively studied
Vitamin B12
17 studies
Vitamin B12 status
Extensively studied
Biotin
Filling everyday nutrient gaps
Well studied
Phosphorus
Filling everyday nutrient gaps
Well studied
Iodine
13 studies
Iodine status
Extensively studied
Magnesium
21 studies
Magnesium status
Extensively studied
Selenium
15 studies
Filling everyday nutrient gaps
Extensively studied
Copper
Filling everyday nutrient gaps
Well studied
Manganese
Filling everyday nutrient gaps
Well studied
Fiber Blend
A 2700mg blend of three ingredients, listed by weight.
Supporting role
Apple Powder
Digestive comfort. In the 2700mg Fiber Blend with two others, listed first.
Supporting role
Rice Bran Solubles Powder
10 studies
Filling everyday nutrient gaps. In the 2700mg Fiber Blend with two others, listed second.
Supporting role
Jerusalem Artichoke Inulin Powder
11 studies
Filling everyday nutrient gaps. In the 2700mg Fiber Blend with two others, listed third.
Well studied
Antioxidant/Immune Blend
A 1053mg blend of 12 ingredients, listed by weight.
Supporting role
Beetroot Powder
11 studies
Oxygen delivery to working muscle. In the 1053mg Antioxidant/Immune Blend with 11 others, listed first.
Well studied
Acerola Extract
Iron status. In the 1053mg Antioxidant/Immune Blend with 11 others, listed second.
Supporting role
Eleuthero Root Powder
Energy without a stimulant. In the 1053mg Antioxidant/Immune Blend with 11 others, listed third.
Well studied
Echinacea Powder
The immune barrier in the nose and throat. In the 1053mg Antioxidant/Immune Blend with 11 others, listed fourth.
Well studied
Acai Juice Powder
A balanced gut microbiome. In the 1053mg Antioxidant/Immune Blend with 11 others, listed fifth.
Supporting role
Green Tea Extract Powder
A healthy inflammatory response. In the 1053mg Antioxidant/Immune Blend with 11 others, listed sixth.
Well studied
Milk Thistle Powder
Everyday liver support. In the 1053mg Antioxidant/Immune Blend with 11 others, listed seventh.
Well studied
Ginkgo Leaf Extract Powder
Blood flow. In the 1053mg Antioxidant/Immune Blend with 11 others, listed eighth.
Well studied
Luo Han Guo Extract Powder
Healthy glucose metabolism. In the 1053mg Antioxidant/Immune Blend with 11 others, listed ninth.
Supporting role
Raspberry Powder
Filling everyday nutrient gaps. In the 1053mg Antioxidant/Immune Blend with 11 others, listed tenth.
Supporting role
Blueberry Powder
11 studies
A balanced gut microbiome. In the 1053mg Antioxidant/Immune Blend with 11 others, listed 11th.
Supporting role
Carrot Powder
Filling everyday nutrient gaps. In the 1053mg Antioxidant/Immune Blend with 11 others, listed 12th.
Supporting role
Alkalizing Blend
A 3847mg blend of ten ingredients, listed by weight.
Supporting role
Barley Grass (Whole Leaf) Powder
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed first.
Supporting role
Alfalfa Grass (Whole Leaf) Powder
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed second.
Supporting role
Wheatgrass (Whole Leaf) Powder
Feeding the bacteria that make butyrate. In the 3847mg Alkalizing Blend with nine others, listed third.
Well studied
Spirulina Powder
17 studies
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed fourth.
Well studied
Chlorella (Cracked Cell) Powder
16 studies
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed fifth.
Well studied
Dulse Powder
Iodine status. In the 3847mg Alkalizing Blend with nine others, listed sixth.
Key driver
Spinach Powder
Methylation. In the 3847mg Alkalizing Blend with nine others, listed seventh.
Supporting role
Broccoli Powder
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed eighth.
Supporting role
Parsley Powder
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed ninth.
Supporting role
Collard Green Powder
Filling everyday nutrient gaps. In the 3847mg Alkalizing Blend with nine others, listed tenth.
Supporting role
Probiotic Blend
A 333mg blend of three ingredients, listed by weight.
Supporting role
Lactobacillus gasseri
A balanced gut microbiome. In the 333mg Probiotic Blend with two others, listed first.
Well studied
Bifidobacterium bifidum
A balanced gut microbiome. In the 333mg Probiotic Blend with two others, listed second.
Supporting role
Bifidobacterium longum
Gut barrier integrity. In the 333mg Probiotic Blend with two others, listed third.
Well studied
DigeZyme (Enzyme Blend)
A 67mg blend of five ingredients, listed by weight.
Supporting role
Amylase
Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed first.
Well studied
Protease
Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed second.
Supporting role
Lactase
Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed third.
Extensively studied
Lipase
Breaking down what you eat. In the 67mg DigeZyme (Enzyme Blend) with four others, listed fourth.
Well studied
Cellulase
Filling everyday nutrient gaps. In the 67mg DigeZyme (Enzyme Blend) with four others, listed fifth.
Supporting role
In context

The gap this formula speaks to.

Public health figures the engine matched to this formula's ingredients. Reported by their source, cited and dated, never written by the brand.

52 more
Jerusalem Artichoke Inulin Powder

Systematic review and meta-analysis of randomized controlled trials, 2024

Across 55 trials in 2,518 adults, inulin-type fructans lowered LDL cholesterol by about 0.14 mmol/L, triglycerides by about 0.06 mmol/L and body weight by about 1 kg.

The American Journal of Clinical Nutrition
Spirulina Powder

Meta-analysis, 2024

Across pooled trials, daily spirulina lowered blood pressure in adults, cutting the top number by about 4.4 and the bottom number by about 2.8.

Phytotherapy Research
Chlorella (Cracked Cell) Powder

Meta-analysis of randomized controlled trials, 2017

Across 19 trials in 797 people, chlorella lowered the top blood pressure number by about 4.5 points and the bottom by about 1.6 points.

Clinical Nutrition
Chlorella (Cracked Cell) Powder

Systematic review and dose-response meta-analysis, 2022

Across 10 trials in 539 adults, chlorella lowered total and LDL cholesterol by about 7.5 and 7.7 mg/dL, with no clear change in triglycerides or HDL.

Complementary Therapies in Medicine
Milk Thistle Powder

Meta-analysis, 2024

Pooling 33 trials in 1,943 adults, silymarin lowered LDL cholesterol by about 17 mg/dL, total cholesterol by about 14 mg/dL, and triglycerides by about 26 mg/dL.

Antioxidants
Spirulina Powder

Meta-analysis, 2023

Across 20 trials, spirulina lowered LDL cholesterol, total cholesterol, and triglycerides by a similar amount each, and modestly raised HDL cholesterol.

Pharmacological Research
Rice Bran Solubles Powder

Meta-analysis, 2024

Across randomised trials, eating rice bran improved blood lipid readings, with lower total and LDL cholesterol in the supplemented groups.

Nutrients
Wheatgrass (Whole Leaf) Powder

Systematic review, 2023

A systematic review of clinical trials of gum arabic reported changes in gut, metabolic and kidney-related measures, with the size of the effect varying by dose and trial.

Biomolecules
Spinach Powder

Meta-analysis, 2025

Pooling five trials, spinach-derived thylakoid supplements lowered reported hunger by 2.415 mm on a rating scale and raised fullness after eating, with the effect scaling with dose.

Nutrition reviews
Raspberry Powder

Randomised trial, 2025

In healthy adults, polyphenols from raspberry leaf tea lowered the post-meal glucose and insulin rise compared with control.

Nutrients
Barley Grass (Whole Leaf) Powder

Randomised trial, 2020

In 18 young adults, a barley leaf drink with an afternoon snack lowered the blood sugar rise afterward and at dinner, most when dinner sugar ran high.

Nutrients
Lactobacillus gasseri

Meta-analysis, 2021

Pooled trials in adults found probiotic supplementation followed by small drops in body weight, body mass index and waist size.

Nutrients
Eleuthero Root Powder

Randomised trial, 2020

In healthy adults, a 12-week combined water extract of eleuthero leaf and Drynaria rhizome raised one memory subscore, figure recall, versus placebo (p = 0.045).

Nutrients
Ginkgo Leaf Extract Powder

Meta-analysis, 2015

Across nine trials in 2,561 older adults with cognitive decline, 240 mg a day of standardized ginkgo extract improved cognitive test scores versus placebo over about 22 to 26 weeks.

The paper
Tan et al., 2015PMID 25114079
Beetroot Powder

Meta-analysis, 2024

Across 11 trials in adults with elevated blood pressure, daily nitrate-rich beetroot juice lowered systolic blood pressure by about 5.3 mmHg versus placebo, with no clear change in the lower number.

Nutr Metab Cardiovasc Dis
Alfalfa Grass (Whole Leaf) Powder

Clinical trial, 1987

Fifteen adults with elevated blood lipids who ate 40 g of heat-treated alfalfa seeds three times daily for eight weeks saw median total cholesterol fall about 17% and LDL cholesterol about 18%, with values returning to starting levels after they stopped.

The paper
Acai Juice Powder

Meta-analysis, 2023

Pooling randomised trials of anthocyanins, the pigment class that acai is rich in, found modest reductions in total and LDL cholesterol.

Frontiers in nutrition
Wheatgrass (Whole Leaf) Powder

Randomised trial, 2024

A randomised placebo-controlled fibre supplement changed aspects of the faecal microbiome in healthy volunteers, with resilience measures reported as exploratory. Acacia fibre is named within the fibre group studied.

Nutrition, Metabolism and Cardiovascular Diseases
Carrot Powder

Randomised trial, 2024

Daily supplementation with carrot-derived rhamnogalacturonan-I altered gut microbiota composition in healthy adults. Composition is a measured community change, not a clinical outcome.

Biomedicine and Pharmacotherapy
Carrot Powder

Systematic review, 2024

Across the reviewed human studies, higher dietary carotenoid intake tracked with more favourable cardiovascular risk markers, an association rather than a demonstrated cause.

Nutrients
Broccoli Powder

Randomised trial, 2025

Broccoli supplementation combined with exercise was tested against exercise alone on metabolic and lipoprotein blood markers in adults.

Nutrients
Echinacea Powder

Meta-analysis, 2007

Pooling 14 studies, echinacea was associated with about 1.4 fewer days of common cold symptoms and lower odds of developing a cold (odds ratio 0.42).

The Lancet Infectious Diseases
Ginkgo Leaf Extract Powder

Systematic review, 2026

Combined trial data linked ginkgo extract to changes in blood sugar, inflammation, lipid and body-measurement markers, all lab and body measures rather than clinical outcomes.

The paper
Zali et al., 2026PMID 42157337
Parsley Powder

Randomised trial, 1999

In 14 adults on a controlled low-flavone diet, a week of daily parsley raised two antioxidant enzyme activities in blood cells versus diet alone, while other markers showed no change.

British Journal of Nutrition
Acerola Extract

Randomised trial, 2011

Encapsulated fruit and vegetable concentrates containing acerola were tested for effects on blood vessel dilation in adults with several metabolic risk markers.

Nutrition journal
Jerusalem Artichoke Inulin Powder

Systematic review and dose-response meta-analysis, 2019

Across 33 trials in adults with high blood sugar, inulin-type fructans lowered fasting blood sugar by about 0.6 mmol/L and a long-term blood sugar marker by about 0.58 percent.

Journal of Translational Medicine
Apple Powder

Systematic review, 2025

Pooling human trials of apple cider vinegar, the review found small reductions in body weight and waist measures in adults with raised blood sugar or excess body weight, and described the evidence base as limited.

Nutrients
Acerola Extract

Randomised trial, 2017

An encapsulated fruit and vegetable juice concentrate containing acerola was tested against placebo in adults with excess body weight for effects on circulating inflammatory markers.

Nutrients
Dulse Powder

Cohort study, 2026

In 49 regular seaweed eaters, urine iodine and estimated iodine intake fell by roughly two thirds within six weeks of stopping seaweed, alongside a drop in a thyroid marker, not a clinical outcome.

European journal of nutrition
Barley Grass (Whole Leaf) Powder

Randomised trial, 2021

In 76 habitual alcohol drinkers, 480 mg of barley sprout extract daily for 12 weeks lowered markers of reactive oxygen species and lipid peroxidation and improved glutathione antioxidant readings.

Antioxidants
Amylase

Randomised trial, 2026

Oral multienzyme supplementation was reported to alter postprandial plasma nutrient concentrations after a mixed meal in healthy adults. Amylase is one enzyme within the blend, and plasma nutrient concentrations are markers rather than clinical outcomes.

The Journal of nutrition
Raspberry Powder

Open-label trial, 2025

A small pilot study of black raspberry supplementation in older adults with excess body weight reported changes in the measured markers. The authors present it as preliminary and hypothesis-generating.

npj Science of Food
Blueberry Powder

Meta-analysis, 2025

Across trials, blueberries produced small improvements in memory and executive function measures.

Biogerontology
Blueberry Powder

Meta-analysis, 2017

Across randomised trials, blueberry supplementation did not produce a detectable change in systolic or diastolic blood pressure.

The paper
Zhu et al., 2017PMID 27654329
Lipase

Case-control, 2026

In adults with elevated liver fat, gene variants including one for a fat-processing enzyme were linked to liver measures, an association rather than a cause.

Nutricion Hospitalaria
Beetroot Powder

Meta-analysis, 2026

Pooling randomised trials of dietary nitrate, the review found only small changes in body weight and body composition measures in adults.

Frontiers in public health
Echinacea Powder

Meta-analysis, 2025

Across 9 randomized trials in children (about 3,000 participants), Echinacea purpurea was associated with fewer upper respiratory episodes (relative risk 0.81) and lower antibiotic use (relative risk 0.18).

Clinical Nutrition ESPEN
Bifidobacterium longum

Meta-analysis, 2023

Pooled trials of a probiotic strain in infants reported measurable effects on the outcomes tracked, along with acceptable tolerability.

Foods
Bifidobacterium bifidum

Systematic review, 2025

Pooled data support vertical mother-to-infant transmission of Bifidobacterium strains in early life, with transmission proportions varying by species and delivery mode.

NPJ Biofilms and Microbiomes
Thiamine

Meta-analysis, 2021

Pooling randomised trials of thiamine in intensive care, the authors did not detect a clear effect on the pooled clinical endpoints, which is a failure to detect a difference rather than a demonstration that none exists.

Journal of Critical Care
Thiamine

Meta-analysis, 2022

Pooling six trials in 364 adults with elevated blood sugar, thiamine at 100 to 900 mg per day showed no detectable effect on HbA1c (-0.02 percent) or fasting glucose, while HDL cholesterol rose by about 0.10 mmol/L.

BMJ Open

Population figures from public health data. Context for the category, not a statement about any individual and not a claim about this product.

What this formula earned

Every one of these is a fact the engine could ground.

Each line below was derived from this formula's own record at the time of verification. Nothing here was written by the brand, and nothing can be added that the evidence does not carry.

  • Studied in people21 human studies on Magnesium back this formula, each one cited.
  • A mechanism that is settledHow Calcium and Iron work is settled pharmacology.
  • Studied together, not just separatelyCalcium and Iron have been studied together, not only separately.
  • Recent work on the recordThe most recent study on this record was published in 2026.
  • Why this formatIt is a powder, so the serving scales to the amount you want and mixes into something you already drink.
  • The exact form, describedThe label names its forms exactly: Calcium carbonate, Ferrous sulfate, Potassium chloride. The record says what each one is and what it suits.
  • An absorption partner in the same servingVitamin C is in the same serving as Iron, where it has a measured absorption role.
  • A declared blend totalFiber Blend declares its total, 2,700 mg per serving, with 3 ingredients listed by weight.
  • Where it comes from and how it is madeCalcium is made by mineral.
  • Positions this formula already qualifies forThis formula already qualifies for positions beyond the one it is sold into, on the evidence it carries.
  • A position nobody is holding yetSome of those positions are ones almost nobody is selling to yet.
  • Interaction screen on the recordEvery active on this label was screened against the interaction record, and the screen is published with it.
Studied together

The combinations the trials actually measured.

Four pairings in this formula have been studied as combinations in human trials. Each finding below is what a named study measured, cited and dated, never written by the brand.

  • Iron + Vitamin CAbsorption

    In a controlled radioiron study in 63 men, adding ascorbic acid to a non-heme iron meal increased iron absorption in proportion to the dose, from about 1.6 times the meal alone at 25 mg to about 9 times at 1000 mg.

    Promising
  • Calcium + MagnesiumStrength

    In a 12-month randomised, double-blind trial, 98 adults aged 50 and over drank a litre a day of either a naturally calcium- and magnesium-rich mineral water or a low-mineral water. The mineral-rich group had fewer falls at the 6-month assessment and higher appendicular muscle mass, with the minerals delivered as drinking water rather than a capsule.

    Promising
  • Folate + Vitamin B12 + Vitamin B6Heart

    In a 2025 network meta-analysis of 16 randomized trials in healthy adults, folic acid taken together with vitamins B6 and B12 lowered blood homocysteine more than any single supplement, with the 1 mg folic acid plus 7.2 mg B6 plus 20 micrograms B12 arm ranked most effective versus placebo (mean difference -1.03 micromol/L, 95% CI -1.71 to -0.36).

    Promising
  • Magnesium + Vitamin B6Calm

    In an 8-week randomized trial of 264 stressed healthy adults with low magnesium, magnesium plus vitamin B6 and magnesium alone reduced perceived stress about equally overall. In the prespecified subgroup that started with severe stress, the combination improved stress scores 24% more than magnesium alone.

    Early

Research strength. Research strength says how much work stands behind the combination. It is never a product score.

Fail closed. Where actives were studied on their own rather than together, each shows on its own evidence, never a combined effect no trial measured.

Independent record. Every finding is cited to a named trial, dated, and never written by the brand.

Findings from trials that studied these actives as a combination. Context for how the actives were tested together, not a statement about any individual and not a claim about this product.

What the trials show

What the trials show about timing.

Time-to-effect windows the engine read from the trial record. Each is a window a named study measured, cited and dated, never written by the brand.

  • Calciumwithin about one to six hours of a single doseMeasured within a day

    A randomised cross-over trial in ten women of mean age 69 gave a single 500 mg dose of calcium as citrate fasting, citrate with a meal, fortified juice or a dairy product meal, with blood drawn before and at 1, 2, 4 and 6 hours. Serum ionised and total calcium increased significantly from baseline over six hours, with the rise similar after fortified juice, delayed when citrate was taken with a meal and smaller after the dairy meal. A separate double-blind cross-over trial in 25 postmenopausal women measured parathyroid hormone and a bone resorption marker 12 hours after a single calcium dose. Ten participants is a small sample, and what moved was blood chemistry, not a sensation.

    Promising
  • Ironwithin 24 hours of a single doseMeasured within a day

    A randomised crossover study in 54 nonanemic young women with plasma ferritin at or below 20 ug/L gave labelled iron sulfate as single fasting morning doses of 40, 60, 80, 160 and 240 mg. Twenty four hours after doses of 60 mg or more, serum hepcidin was raised and fractional iron absorption from the following dose was 35% to 45% lower. Across the dose range a sixfold rise in dose, 40 to 240 mg, produced a threefold rise in iron absorbed, 6.7 to 18.1 mg. Total iron absorbed from three doses inside 24 hours was not significantly greater than from two morning doses. The measure was iron absorption and serum hepcidin, not a symptom.

    Promising
  • Vitamin Cwithin 24 hours of a single doseMeasured within a day

    In a randomised crossover trial, 12 healthy adults consumed 101.7 mg of vitamin C as a powder, as raw fruits and vegetables, or as juice, and plasma vitamin C rose after every intake form, with plasma and urinary levels tracked over the 24 hours following the single dose.

    Strong
  • Vitamin Kabout four weeks of daily useBuilds with daily use

    A double-blind randomised dose-finding trial gave 60 postmenopausal women aged 50 to 69 either 0, 50, 100 or 200 micrograms of menaquinone-7 daily for four weeks on a controlled diet. The ratio of carboxylated to undercarboxylated osteocalcin rose dose dependently, with significant differences from the 0 microgram group at 100 and 200 micrograms. A companion 12-week trial in 120 people aged 20 to 69 confirmed the change at 100 micrograms daily. Both studies were run by authors affiliated with the R and D division of J-Oil Mills. An independent 8-week double-blind trial in 55 healthy prepubertal children found the same direction at 45 micrograms daily. What was measured is a blood marker of vitamin K status, not bone density and not a sensation.

    Promising
  • Vitamin Kthree years of daily use, with measurements at one, two and three yearsBuilds with daily use

    A double-blind randomised trial gave 244 healthy postmenopausal women either placebo or 180 micrograms of menaquinone-7 daily for three years, with bone mineral density measured by DXA at baseline and after each year. Menaquinone-7 decreased the age-related decline in bone mineral content and bone mineral density at the lumbar spine and femoral neck, but not at the total hip. The effect is a slowed decline rather than a gain, and the trial ran three years rather than weeks.

    Promising
  • Thiamineabout 18 to 30 days of restricted intakeBuilds with daily use

    In the controlled depletion study the EFSA reference opinion reviews, restricting thiamin intake to 0.009 to 0.015 mg/MJ for 30 days brought urinary free thiamin excretion from a mean of 0.283 mg/24 h down to undetectable levels by day 18 of the depletion period.

    Promising
16 more
  • Thiamineabout 1 week of renewed intakeBuilds with daily use

    In the same depletion and repletion record the EFSA reference opinion reviews, erythrocyte transketolase activity fell progressively to about 75% of baseline during the 30-day depletion period and returned to its baseline value after 1 week of thiamin repletion.

    Promising
  • Riboflavinabout 8 weeks of daily intakeBuilds with daily use

    In an intervention the EFSA reference opinion reviews, adults whose baseline riboflavin intake and status were unknown received 5 mg/day of riboflavin for 8 weeks, and haemoglobin concentration, haematocrit and erythrocyte count all rose significantly over that period.

    Early
  • Vitamin B6about 20 to 40 days to clear after stoppingBuilds with daily use

    An expert consensus on vitamin B6 use, developed by a six-member Delphi panel with a structured evidence-quality assessment, calculated from pharmacokinetic parameters that complete clearance of vitamin B6 from the body takes a washout period of about 20 to 40 days after intake stops.

    Early
  • Folatea median of about 36 weeks of daily intakeBuilds with daily use

    A systematic review and Bayesian meta-analysis drew on 108 articles from 14,002 screened records and modelled blood folate against folic acid intake using one-compartment pharmacokinetic models. Red blood cell folate rose 1.78 fold from baseline to steady state at 375 to 570 ug folic acid per day, and reaching that steady state took a median of 36 weeks, 95% credible interval 27 to 52 weeks. Serum or plasma folate rose 11.6% for every 100 ug per day of folic acid intake, 95% credible interval 8.4 to 14.9.

    Strong
  • Folateabout 18 days for serum folate to reach its maximumBuilds with daily use

    A kinetic study in six healthy men aged 22 to 31 gave 3.6 umol per day, 1.6 mg, of deuterium-labelled folic acid for four weeks, with folate tracked in serum, erythrocytes and urine by microbiological assay and gas chromatography mass spectrometry. Serum folate reached its maximum concentration in about 18 days, while isotopic labelling of erythrocyte folate kept rising across the whole four weeks. After supplementation stopped, red blood cell folate and urinary folate excretion declined linearly, and serum folate fell with a slow-phase half-life of 18.7 days. One study, six men, no control group.

    Early
  • Vitamin B12about 16 weeks of daily oral useBuilds with daily use

    A randomised, double-blind, parallel-group dose-finding trial in 120 older people with mild vitamin B12 deficiency, defined as serum B12 of 100 to 300 pmol/L with methylmalonic acid at or above 0.26 umol/L, gave daily oral cyanocobalamin at 2.5, 100, 250, 500 or 1000 ug for 16 weeks. Mean plasma methylmalonic acid fell 16%, 16%, 23%, 33% and 33% across those doses. Daily doses of 647 to 1032 ug accounted for 80% to 90% of the estimated maximum reduction. The window was measured on a blood marker of B12 status, not on a symptom.

    Promising
  • Vitamin B12serum levels peak about seven hours after a single tabletMeasured within a day

    An open-label randomised single-dose pharmacokinetic study in 20 healthy men aged 20 to 45, conducted and authored by staff of Emisphere Technologies, the developer of the SNAC carrier under test, measured serum vitamin B12 after one 5 mg cyanocobalamin tablet, with six men on the marketed tablet. Time to peak serum B12 was 6.83 hours for the marketed tablet and 0.5 hours for the carrier coformulation. Absolute bioavailability was 2.16% and 5.09% respectively. One trial, six men per arm. Serum concentration was measured, not any symptom.

    Early
  • Biotinabout 5 to 6 months of daily useBuilds with daily use

    In an open trial with no placebo arm, 71 patients with brittle or splitting fingernails took 2.5 mg of biotin a day. Of the 45 cases that could be evaluated, 41 were rated as having firmer and harder nails after an average of 5.5 months of treatment, standard deviation 2.3 months. The rating was clinical judgement rather than an instrument reading, and there was no control group, so the window describes when the raters recorded change, not a placebo adjusted effect.

    Early
  • Phosphorusthe hours after a mealMeasured within a day

    A systematic review of ten randomised crossover trials in 225 healthy adults aged 18 to 64 examined inorganic phosphorus supplementation taken with meals against postprandial metabolic outcomes. Three of the four studies measuring diet-induced thermogenesis reported a significant positive association with phosphorus in the hours after eating. The reviewers temper the finding: few studies, modest samples, methodological heterogeneity, and association rather than established cause.

    Early
  • Iodinefrom about eight weeks, deepening through twenty-four weeksBuilds with daily use

    In a 24 week randomised double-blind placebo-controlled trial in 112 mildly iodine-deficient New Zealand adults aged 18 to 40, 150 micrograms of iodine a day as potassium iodate lowered thyroglobulin, a blood marker of iodine status, by 12 percent at 8 weeks, 20 percent at 16 weeks and 27 percent at 24 weeks compared with placebo. Median urinary iodine reached 168 micrograms per litre against 79 on placebo. TSH and free T4 stayed within normal range and did not change significantly.

    Promising
  • Seleniumabout ten weeks of daily useBuilds with daily use

    In a 12 week randomised double-blind placebo-controlled trial in 119 healthy UK adults aged 50 to 64, mean plasma selenium rose from 95.7 ng/mL at baseline to steady state by week 10, reaching 118.3, 152.0 and 177.4 ng/mL on 50, 100 and 200 micrograms a day of selenium-enriched yeast. Plasma selenoprotein P rose in every selenium arm. Platelet glutathione peroxidase activity did not change significantly at any dose or form.

    Promising
  • Copperabout four to eight weeks of daily useBuilds with daily use

    In an 8 week pilot with a parallel placebo group, 8 young women taking 2 mg of copper a day as copper glycinate showed a 9 percent mean rise in serum ceruloplasmin and a 75 percent rise in diamine oxidase, alongside a 39 percent fall in plasma F2-alpha isoprostanes. Erythrocyte copper-zinc superoxide dismutase did not change. In a separate 4 week double-blind crossover in 20 men with moderately high cholesterol at the same 2 mg a day, copper moved no measure across the whole group and raised superoxide dismutase and diamine oxidase only in the 10 men who started below the median. Both are small and both measured enzymes in blood, not a symptom.

    Early
  • Jerusalem Artichoke Inulin Powderabout four weeks of daily useBuilds with daily use

    In a randomised double-blind placebo-controlled trial in constipated elderly volunteers (25 in the inulin arm), 15 g per day of chicory native inulin significantly raised total faecal bacteria and bifidobacteria counts after 28 days, alongside reported reductions in defecation difficulty. Flatulence was reported but did not stop participation. A separate four-week randomised trial funded by the ingredient maker BENEO gave 8 g per day to 18 subjects with reduced tolerance of intestinal gas and found gas retention fell 22 percent against baseline, a change that did not separate from placebo, with higher bifidobacteria counts against placebo.

    Promising
  • Beetroot Powderabout two to three hours after a single doseMeasured within a day

    In a balanced crossover trial, 10 healthy men ingested 70, 140 or 280 mL of concentrated beetroot juice, carrying 4.2, 8.4 and 16.8 mmol inorganic nitrate, with resting plasma nitrate and nitrite tracked over 24 hours. Plasma nitrite rose dose dependently and the peak change occurred at approximately 2 to 3 hours after ingestion. Exercise testing was timed to 2.5 hours postingestion on that basis, where 280 mL lowered steady state oxygen uptake during moderate cycling by 3.0 percent, with a non-significant 1.7 percent reduction at 140 mL.

    Promising
  • Milk Thistle Powderabsorbed and largely cleared within about 8 hoursMeasured within a day

    In a randomised, open-label crossover pharmacokinetic study, 12 healthy volunteers took single doses of two milk thistle supplement formulations, with blood sampled over 8 hours. Silybin A and B were rapidly absorbed and eliminated in both, and the soft-gel formulation reached higher peak and total exposure than the powdered capsule.

    Early
  • Blueberry Powderabout 12 weeks of daily useBuilds with daily use

    In a small preliminary study, nine older adults with early age-related memory changes drank wild blueberry juice daily for 12 weeks and improved on paired-associate learning and word-list recall, with scores compared against a demographically matched group given a berry placebo drink. One study of nine people, juice rather than a capsule.

    Early

Windows measured in the cited trials. Context for how the active behaves over time, not a statement about any individual and not a claim about this product.

General timing

How each ingredient usually behaves over time.

12 ingredients, from each one's own page.

6 more

How each ingredient usually behaves over time, from its own page on IngredientMD. General timing for the ingredient, not a measurement of this product.

Chemical form

The same ingredient, carried differently.

What each form is, and where it fits in a formula. Measured findings carry the study that reported them.

  • Riboflavin

    The free vitamin B2 molecule, an isoalloxazine ring joined to a ribitol sugar chain, supplied as the unmodified crystalline compound with no added salt or phosphate group.

    Fits
    It is the form most panels list simply as riboflavin or vitamin B2.
    Trade-off
    It is intensely yellow and only sparingly water soluble, so it can tint a finished product and tends to resist dissolving cleanly in a liquid or a fast-melt format.
  • Jerusalem artichoke inulinActive and formulation aid

    Fructan from Helianthus tuberosus tubers, linear like chicory inulin but with a different chain-length spread and residual sugar profile.

    Fits
    Whole-food-positioned products and powders that also want the tuber's other constituents.
    Trade-off
    Composition varies more between harvests than a purified chicory grade.
  • Carrot powder

    Sliced carrot dried at elevated temperature then milled. Heat disrupts cell walls, which raises carotene release, while some heat-labile compounds and volatile flavour are lost.

    Fits
    Blends and food applications where cost per kilogram and colour matter more than compound fragility.
    Trade-off
    Thermal exposure drives some trans to cis carotene isomerisation and reduces vitamin C content relative to the fresh root.
  • Whole-leaf powder

    Whole young leaf dried and milled, keeping the cellulose cell wall material as well as the soluble fraction

    Fits
    Formulas where the fibre fraction is wanted alongside the pigments and micronutrients
    Trade-off
    Grittier texture, more insoluble fibre per serving, and the mineral-binding fibre and phytate travel with it
  • Spirulina powder

    Harvested filaments washed and spray-dried, keeping protein, pigment, fatty acid and mineral content in the whole-cell matrix.

    Fits
    Smoothies, blend powders and bulk dosing where a large serving is practical.
    Trade-off
    Strong marine flavour and deep colour carry into anything it is mixed with, and spray-drying uses heat that can affect the heat-sensitive pigment fraction.
  • Dulse powderActive and formulation aid

    Dried thallus reduced by milling. Composition matches the leaf it came from, with greater surface area

    Fits
    Blending into capsules, seasonings and powdered formulas where a uniform particle is needed
    Trade-off
    Greater surface area increases exposure to oxygen and light during storage, and milling does not reduce batch-to-batch compositional spread
  • 1 more
  • Ethyl ester (EE)

    During concentration, EPA and DHA are cleaved from glycerol and each bound individually to ethanol, so every fatty acid rides on its own ethyl group rather than a shared glycerol backbone. This arrangement allows a high EPA and DHA percentage.

    Fits
    Suits high-concentration products where a large EPA and DHA figure per capsule is the goal and the manufacturer stops at the ester stage rather than re-esterifying.
    Trade-off
    Each fatty acid is bound to ethanol rather than a shared glycerol backbone, a more processed arrangement than either triglyceride form, and one that does not blend into a food-oil matrix as readily.

    In a six-month double-blind RCT in 150 adults, the rise in the omega-3 index (EPA and DHA in red blood cell membranes) with the ethyl ester form was smaller than with an equal dose of re-esterified triglyceride. A two-week trial found lower serum appearance versus natural fish oil.

Descriptions of the form itself, read from the cited studies. Not a comparison between products and not a statement about any individual.

Format

Powder

It is a powder, so the serving scales to the amount you want and mixes into something you already drink.

Best forGram-scale actives: creatine, collagen, protein, electrolytes, beta-alanine.

Questions shoppers ask

Is Super Greens independently verified?
Yes. IngredientMD reviewed this formula independently and verified it in Oct 2026. The verdict is earned, not bought: brands can't edit or purchase it.
What's in Super Greens?
Super Greens is built on Calcium, Iron, Potassium, Vitamin A, Vitamin C, Vitamin K, and more. Each ingredient links to its own evidence page on IngredientMD.
Were ingredient interactions checked?
Yes. The combination was screened against 7,100 documented interactions for these actives in IngredientMD's interaction database.
Who is IngredientMD?
IngredientMD is an independent supplement-science platform. We analyze ingredients and formulas against clinical research, and we verify products only when they clear our bar. Labs run the tests. We review the results.
Sell a formula this good?

Put an earned verification on your own product page.

Get verified

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This record is not medical advice. Always consult your healthcare provider before starting any supplement regimen.

Independent review by IngredientMD, not commissioned by Nested NaturalsWork at Nested Naturals? This verification is yours to claim →