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Ingredients/Herb/Cramp Bark (Viburnum opulus)

Cramp Bark (Viburnum opulus).

Strength pending.The research strength is not set yet.

A traditional European bark taken for comfort low in the abdomen around the monthly cycle. It is astringent and tannin-rich, which is what you taste in it.

500 to 1,000mgDaily amount

Reviewed March 2026

CBHerb
Cramp Bark (Viburnum opulus)IngredientMD
Category
Herb

What Cramp Bark (Viburnum opulus) is, and what it does.

Does it work
It suits women who want a traditional herbal option through the days around their period, often alongside magnesium or ginger. Tradition is well documented here; trials are not.
How much to take
Start with 500 to 1,000mg a day of the dried bark or its tincture equivalent, used across the days you want it rather than all year round.
Time to feel it
Traditional use is situational: a dose when it's wanted, with any settling described within an hour or two. Nobody has measured an onset in a controlled trial.
The first dose
The drying, astringent taste is the first thing most people notice. Any settling low in the abdomen is described within an hour or two of a dose.
With regular use
Taken steadily across a month, herbalists position it around comfort through the monthly cycle. There's no long-term human data on daily use, so that pattern rests on tradition.
How well tolerated
Generally well tolerated in traditional use. Tannins bind iron and protein, so space it from an iron serving, and check with your doctor if you're pregnant or on a blood thinner.
How it feels
The astringent, drying taste is what most people notice first. Some describe a mild settling low in the abdomen. It isn't sedating and it doesn't cloud your head.
The overlooked benefit
Cold water pulls out very little of the bark's coumarins. A hot decoction or an alcohol tincture carries a different mix of compounds than a cold infusion of the same bark.

500 to 1,000mg a day is where Cramp Bark (Viburnum opulus) works.

How much to take a dayLimited data
500 to 1,000mg
Daily maintenanceThe everyday amount, and where most daily supplements sit. This is the one you take month after month.
2,000mgClinical territory. Trials run high on purpose, for a set number of weeks, against one measured outcome. Impressive to hit, and not what a daily product is for.
Above 3,000mgPast what the research covers. More capsules rather than more effect.
MORE EFFECT ↑01,000mg2,000mg plateauDAILY DOSE →
The shaded band is where the dosing trials landed.

Source: Traditional herbal medicine. European monograph for Viburnum opulus.

The proof, claim by claim.

These words describe the research, not the molecule's worth. Research strength is how much work stands behind one claim, and it is never a product score.

Cramp Bark (Viburnum opulus) has emerging evidence. Based on 6+ studies.

  • traditional use for comfort around the monthly cycleNarrative review
  • smooth muscle relaxing activity in laboratory tissue preparationsAnimal study
  • condensed tannin and proanthocyanidin content of the barkIn vitro study
PubMedCochraneClinicalTrials.govNIH ODSSUPP.AILabs test. IngredientMD verifies.PubMedCochraneClinicalTrials.govNIH ODSSUPP.AILabs test. IngredientMD verifies.

Questions people ask about Cramp Bark (Viburnum opulus).

When should I take it?
Timing matters less than consistency. Pick a time that works for you and take it daily.
Can I take it with other supplements?
Usually fine. The main thing to watch is not doubling up on the same ingredient from different products. If you're on prescription meds, check with your pharmacist first.
Any side effects to watch for?
Most people tolerate it well at recommended doses. GI upset is the most common complaint with any supplement. Start with a lower dose and work up. If something feels off, stop and reassess.
Who benefits most from this?
People who've already covered the basics (diet, sleep, exercise) and want to fine-tune. It's not essential, but could be worthwhile for the right person.
Pairs well with21 on file

Why these belong in the same formula. Each row says what the basis is, from settled biochemistry through to a trial that measured the pair.

Cramp Bark (Viburnum opulus) + Magnesium Glycinateshared smooth muscle relaxation mechanism

Magnesium acts as a natural calcium antagonist at the smooth muscle cell, the same relaxation target cramp bark's scopoletin and viburnin address. The pairing is standard in cyclical comfort formulas.

Cramp Bark (Viburnum opulus) + Magnesiumshared smooth muscle relaxation mechanism

Magnesium limits calcium entry that drives smooth muscle contraction, working alongside cramp bark's antispasmodic constituents. Both act on muscle tone rather than on pain signalling.

Cramp Bark (Viburnum opulus) + Chasteberry (Vitex agnus-castus)long-standing cyclical formulation practice

Vitex works at the pituitary on prolactin signalling while cramp bark acts locally on uterine smooth muscle tone. The two cover the hormonal and the muscular side of the monthly cycle.

Cramp Bark (Viburnum opulus) + Gingerprostaglandin pathway complement

Ginger gingerols damp prostaglandin production, which is what drives the contractions cramp bark relaxes. Signal and muscle response are addressed at two points.

Cramp Bark (Viburnum opulus) + Black Cohoshtraditional women's formula pairing

Black cohosh acts on central serotonergic pathways while cramp bark acts on peripheral smooth muscle. Traditional cyclical formulas combine the two roles.

Dong quai coumarins support pelvic circulation while cramp bark eases muscle tone. They are long-standing companions in cyclical blends.

Cramp Bark (Viburnum opulus) + Valerian Rootantispasmodic plus calming pairing

Valerian has its own smooth muscle relaxing action alongside its GABAergic calming effect, which reinforces cramp bark's antispasmodic role. The combination is traditional in evening formulas.

Chamomile apigenin and bisabolol relax smooth muscle in the gut and pelvis, overlapping cramp bark's target. Both appear in classic antispasmodic teas.

Cramp Bark (Viburnum opulus) + Peppermint Oil (Enteric-Coated)shared calcium channel smooth muscle mechanism

Menthol reduces calcium influx into smooth muscle, the same relaxation route cramp bark uses. The two are combined where gut and pelvic muscle tension overlap.

Cramp Bark (Viburnum opulus) + passionflowerTraditional Western herbal formulation practice; both are used in the same calming preparations

Cramp bark and passionflower appear together in long-standing Western herbal formulas aimed at relaxation and comfort during the monthly cycle. The pairing rests on formulation tradition and shared use rather than on a combination trial. No controlled human study of the two together is available. Read it as customary practice, not measured effect.

Cramp Bark (Viburnum opulus) + lemon-balmTraditional pairing in relaxing herbal blends

Lemon balm is commonly blended with cramp bark in teas and tinctures intended to support a settled feeling in the evening. Both are aqueous or hydroethanolic bark and leaf preparations that formulate together without technical conflict. The basis is formulation custom. There is no combination trial to cite.

Cramp Bark (Viburnum opulus) + magnolia-barkBoth used in blends supporting a calm state; overlapping sedative-leaning direction

Magnolia bark honokiol and magnolol act on GABA-A modulation, and cramp bark preparations are used for relaxation, so a blend of the two pushes in the same direction. That direction is worth flagging for anyone already taking something calming in the evening. The interaction is inferred from each ingredient's own pharmacology, not from a study of the pair.

Cramp Bark (Viburnum opulus) + l-theanineOverlapping calming direction in evening formulas

L-theanine shifts alpha-band cortical activity and is used in the same evening products where cramp bark appears. The two are combined for a shared relaxation angle rather than for any tested interaction. Nothing has measured the pair together in people.

Cramp Bark (Viburnum opulus) + white-willow-barkBoth bark preparations carry salicylate-type phenolics; overlapping platelet-facing direction

White willow bark supplies salicin, which is converted to salicylate and has a known effect on platelet function. Viburnum bark preparations have been described as containing salicylate-type constituents, so the combination stacks in one direction. This is a caution row rather than a benefit row. It rests on constituent chemistry, not on a trial of the two together.

Cramp Bark (Viburnum opulus) + vitamin-b6-pyridoxineCofactor chemistry, combined in the same cycle-support formulas

Pyridoxal-5-phosphate is the cofactor for the decarboxylases and transaminases that build and clear monoamine neurotransmitters, which is settled biochemistry independent of any botanical. Formulators pair it with cramp bark in cycle-support blends for that cofactor role. The two act by unrelated routes and do not compete for absorption.

Cramp Bark (Viburnum opulus) + calciumElectrolyte handling in smooth muscle contraction

Smooth muscle contraction depends on calcium entry and the calcium-calmodulin activation of myosin light chain kinase, which is textbook physiology. Products aimed at comfort during the cycle often carry calcium alongside cramp bark for that reason. The rationale is mechanistic; no trial has measured the pair.

Cramp Bark (Viburnum opulus) + potassiumMembrane potential and smooth muscle excitability

Potassium sets the resting membrane potential that governs how readily smooth muscle depolarises, established physiology that applies regardless of what botanical sits beside it. Cramp bark blends sometimes include potassium salts on that basis. The relationship is mechanistic and has not been tested as a combination.

Cramp Bark (Viburnum opulus) + omega-3-fish-oil-epadhaEicosanoid substrate shift, used in the same category of formulas

EPA and DHA compete with arachidonic acid for cyclooxygenase and lipoxygenase, shifting the eicosanoid profile produced during the monthly cycle. That substrate competition is established lipid biochemistry. Pairing it with cramp bark is a formulation choice that adds a different route rather than a duplicated one.

Cramp Bark (Viburnum opulus) + turmeric-curcuminDifferent pathway, same product category

Curcuminoids act on NF-kB signalling and eicosanoid enzymes, a route that does not overlap with the smooth-muscle angle attributed to cramp bark. Blends carry both to cover two mechanisms at once. No study has measured the pair.

Cramp Bark (Viburnum opulus) + boswellia-serrataComplementary route in comfort formulas

Boswellic acids act on 5-lipoxygenase, a distinct arm of the eicosanoid cascade from the one usually discussed for cramp bark. The two are formulated together for that non-overlap. This is formulation reasoning, not combination evidence.

Cramp Bark (Viburnum opulus) + cinnamonTraditional pairing in warming cycle-support teas

Cinnamon bark is a customary companion to cramp bark in warming teas and tinctures used around the monthly cycle. The pairing is culinary and traditional in origin. Nothing measures the combination.

Who should be cautious

Nothing specific on file for Cramp Bark (Viburnum opulus). Match the label to the daily amount above, and tell your doctor what you take.

Not medical advice. Show the label to your pharmacist.

What Cramp Bark (Viburnum opulus) actually does.

Established

The bark carries condensed tannins and proanthocyanidins, which is why aqueous decoctions taste astringent and why tannin-rich preparations can bind dietary protein and non-heme iron in the gut lumen.

Established

Coumarins and the more lipophilic bark constituents extract poorly into cold water and better into hydroethanolic menstruums, which is why tinctures and hot decoctions differ in composition from a cold infusion of the same bark.

Grown, 6 steps on record

Where Cramp Bark (Viburnum opulus) comes from.

The bark of the guelder rose shrub is peeled, dried and ground. It is then either capsuled as-is or soaked in water or alcohol to pull the plant compounds out, and that liquid is bottled as a tincture or dried into a powder.

Made from a plant. What ends up in the capsule tracks the harvest, so batch testing and a stated marker matter more here than with a made molecule.

Starts as
Viburnum opulus stem and branch bark

Bark is stripped from stems and branches of the guelder rose shrub, traditionally in spring when the bark separates cleanly from the wood.

Converted by
Drying and size reduction

Bark is dried to a low moisture content to stop enzymatic browning and microbial growth, then cut or milled to a defined particle size.

Extracted by
Hot water decoction or hydroethanolic maceration

Water alone pulls the tannins and other polar constituents; ethanol-water menstruums also carry the coumarin fraction, which is why tinctures and teas are chemically different products.

Purified by
Filtration and pressing

Spent bark is pressed and the liquor filtered to remove particulates before concentration.

Standardised to
Ratio declaration rather than marker assay

Most commercial cramp bark is sold on an extraction ratio or as whole powdered bark; a validated marker assay is not standard for this species.

Ends up as
Tincture, powder or dried extract

The liquor is either bottled as a tincture, or vacuum concentrated and dried onto a carrier for capsules and tablets.

Getting Cramp Bark (Viburnum opulus) from food.

The whole-food sources on file. A supplement closes the gap, it does not replace dinner.

White Willow Bark Tea

A gram-for-gram figure (how much of each you would eat to match a dose) will appear here once it is sourced and reviewed. This page will not print a number it cannot cite.

The forms it comes in.

Cramp bark, cut and siftedWhole dried stem bark, no solvent processing beyond drying and millingFits Decoctions and home preparations where the user controls extraction time and strengthTrade-off Constituent content varies with harvest season and storage, and cold water pulls the water-soluble fraction only
Cramp bark tincture, typically 1:5 in 40 to 45 percent ethanolEthanol-water extract that carries both the polar tannin fraction and the more lipophilic coumarinsFits Liquid dosing and blends with other tinctures; the ethanol keeps the extract stable in solutionTrade-off Carries ethanol, and the taste is strongly astringent
Cramp bark powderMilled whole bark, no extraction step, so the full matrix including fibre is presentFits People who want the unextracted bark and a fixed weight per capsuleTrade-off Extraction depends entirely on gastric and intestinal conditions, so delivered constituent amounts are less predictable than with a finished extract
Cramp bark extract, ratio-declared (for example 4:1)Solvent extract dried onto a carrier; ratio describes starting material to finished extract, not a marker percentageFits Capsules and tablets where a smaller fill weight is neededTrade-off A ratio is not a standardisation, so two 4:1 extracts can differ in actual constituent content
What the strongest studies found

The essence, in one line each.

  1. A pharmacology review of botanicals used in women's health that names Viburnum among the traditional entries and describes the supporting phytochemical and clinical literature for that group as thin.Narrative review. Dietz et al., 2016 (Pharmacological Reviews). PMID 27677719

These are the studies our verdict leans on, chosen from the 1 we read for Cramp Bark (Viburnum opulus). The full linked list is below.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.